Development Level

Tbio 8 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased food intake 1 | 13
embryonic lethality prior to t... 1 | 278
tremors 1 | 39

Disease

Carcinoma 7 | 11,493
osteosarcoma 7 | 7,950
ovarian cancer 7 | 8,520
medulloblastoma, large-cell 6 | 6,241
Breast cancer 5 | 3,578
Intellectual disability 5 | 1,016
atypical teratoid / rhabdoid tumor 5 | 5,112
Breast Neoplasms 4 | 445
Dull intelligence 4 | 645
Hereditary Breast and Ovarian Cancer Syndrome 4 | 14
Kidney cancer 4 | 2,613
Low intelligence 4 | 645
Mammary Neoplasms 4 | 425
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
Short stature 4 | 531
Small head 4 | 374
adult high grade glioma 4 | 3,801
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
primitive neuroectodermal tumor 4 | 3,035
psoriasis 4 | 6,694
Acquired scoliosis 3 | 281
Almond-shaped eyes 3 | 23
Autosomal recessive predisposition 3 | 1,442
Cancer 3 | 2,499
Chromosome Breakage 3 | 36
Cognitive delay 3 | 608
Curvature of spine 3 | 282
Decreased platelet count 3 | 111
Fanconi anemia 3 | 56
Global developmental delay 3 | 608
Increased chromosomal breakage 3 | 27
Irregular hyperpigmentation 3 | 33
Leukopenia 3 | 72
Mental and motor retardation 3 | 608
Pick disease 3 | 1,894
Pyridoxine-responsive sideroblastic anemia 3 | 17
Radial aplasia/hypoplasia 3 | 29
Short palpebral fissure 3 | 38
Thrombocytopenia 3 | 197
hypopigmented skin patch 3 | 59
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
Anemia 2 | 365
Ataxia telangiectasia 2 | 34
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 2 | 9
Esophageal atresia 2 | 43
Esophageal atresia with or without tracheoesophageal fistula 2 | 21
Genetic Predisposition to Disease 2 | 27
Head and Neck Neoplasms 2 | 26
Liver cancer 2 | 604
Lung Neoplasms 2 | 232
Malignant neoplasm of breast 2 | 15
Nijmegen breakage syndrome 2 | 24
Ovarian Neoplasms 2 | 102
Tracheoesophageal Fistula 2 | 36
acute myeloid leukemia 2 | 783
diabetes mellitus 2 | 1,728
esophageal atresia/tracheoesophageal fistula 2 | 22
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
malignant mesothelioma 2 | 3,232
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
ovarian neoplasm 2 | 99
progressive supranuclear palsy 2 | 676
Autosomal recessive Robinow syndrome 1 | 27
Basal cell carcinoma 1 | 54
Carcinoma, Basal Cell 1 | 28
Cholera 1 | 34
Chronic kidney disease stage 5 1 | 31
Congenital Heart Defects 1 | 58
Congenital heart disease 1 | 93
Cystic kidney 1 | 30
DOID:2627 1 | 94
Dysplastic nevus syndrome 1 | 7
Esophageal Neoplasms 1 | 69
Familial cancer of breast 1 | 12
Glioma 1 | 74
Hydronephrosis 1 | 89
Hyperopia 1 | 70
Liver Cirrhosis, Experimental 1 | 769
Lobular neoplasia 1 | 15
Lynch syndrome 1 | 35
Malignant tumor of prostate 1 | 26
Mammary Neoplasms, Experimental 1 | 154
Mesothelioma 1 | 38
Microcephaly 1 | 166
Nephroblastoma 1 | 51
Pancreatic carcinoma, familial 1 | 8
Premature Menopause 1 | 31
Renal cyst 1 | 30
Somatic mutation 1 | 61
Wilms Tumor 1 | 28
Xeroderma pigmentosum 1 | 43
Xeroderma pigmentosum group D 1 | 33
Xeroderma pigmentosum variant type 1 | 4
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 2 | 4,145

GO Process

telomere maintenance via recom... 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Telomerase protein component 1 TEP1 Tbio Enzyme -1.74492 50.6 71
DNA repair protein XRCC3 XRCC3 Tbio Non-IDG -2.50791 314.0 414
Structural maintenance of chromosomes protein 6 SMC6 Tbio Non-IDG -1.42371 20.0 115
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.46139 2647.6 209
Structural maintenance of chromosomes protein 5 SMC5 Tbio Non-IDG -1.90832 85.0 109
E3 SUMO-protein ligase NSE2 NSMCE2 Tbio Enzyme -1.37520 25.7 196
DNA repair protein RAD51 homolog 3 RAD51C Tbio Non-IDG -1.92798 88.3 269
DNA repair protein RAD51 homolog 1 RAD51 Tchem Non-IDG -3.82649 6590.0 594
DNA repair protein RAD50 RAD50 Tbio Non-IDG -1.42369 23.8 305