Development Level

Tbio 24 | 11,445
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased grip strength 2 | 116
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal retinal inner nuclear... 1 | 8
abnormal retinal vasculature m... 1 | 27
abnormal snout morphology 1 | 23
cataract 1 | 92
decreased circulating amylase ... 1 | 28
decreased circulating phosphat... 1 | 27
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
excessive tearing 1 | 2
hyperactivity 1 | 148
increased grip strength 1 | 41
increased mean corpuscular vol... 1 | 92
male infertility 1 | 123
premature death 1 | 5

Disease

ovarian cancer 15 | 8,520
Carcinoma 14 | 11,493
osteosarcoma 13 | 7,950
psoriasis 10 | 6,694
medulloblastoma, large-cell 9 | 6,241
lung cancer 7 | 4,740
group 3 medulloblastoma 6 | 4,104
Intellectual disability 5 | 1,016
Pick disease 5 | 1,894
astrocytic glioma 4 | 2,597
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
progressive supranuclear palsy 4 | 676
Breast Neoplasms 3 | 445
Neoplasm Metastasis 3 | 168
acute myeloid leukemia 3 | 783
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
Acquired metabolic disease 2 | 336
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Bladder urothelial carcinoma 2 | 4
Breast cancer 2 | 3,578
Cardiomyopathy 2 | 116
Cataract 7 2 | 32
Cognitive delay 2 | 608
Delayed speech and language development 2 | 112
Disease Models, Animal 2 | 155
Dull intelligence 2 | 645
Fetal Growth Retardation 2 | 189
Global developmental delay 2 | 608
Infant, Small for Gestational Age 2 | 176
Intrauterine retardation 2 | 176
Isolated growth hormone deficiency 2 | 30
Language Delay 2 | 112
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Microcephaly 2 | 166
Multiple myeloma 2 | 1,332
Muscle Spasticity 2 | 195
Myositis 2 | 30
Neoplasm Invasiveness 2 | 161
Poor school performance 2 | 645
Short stature 2 | 531
Small head 2 | 374
Speech Delay 2 | 112
Speech impairment 2 | 112
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
interstitial lung disease 2 | 298
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
primitive neuroectodermal tumor 2 | 3,035
sonic hedgehog group medulloblastoma 2 | 467
Acne 1 | 52
Agoraphobia 1 | 21
Atrioventricular block 1 | 35
Broad thumbs 1 | 28
Charcot-Marie-Tooth disease 1 | 62
Chromosome 15q24 deletion syndrome 1 | 12
Combined oxidative phosphorylation deficiency 1 | 14
Conduct disorder 1 | 33
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Dyskeratosis congenita 1 | 24
Epileptic encephalopathy 1 | 26
Exotropia 1 | 35
Fibrosis 1 | 44
Fine hair 1 | 42
Gestational diabetes 1 | 26
Gross motor development delay 1 | 21
Hyperplasia of nose 1 | 23
Hypertrophy of nose 1 | 23
Hypoplastic feet 1 | 66
Large nose 1 | 23
Leigh disease 1 | 100
Narrow face 1 | 54
Papillary carcinoma 1 | 6
Peripheral Neuropathy 1 | 134
Phenylketonuria 1 | 20
Precancerous Conditions 1 | 80
Premature ovarian failure 1 | 65
Recurrent infections 1 | 48
Renal agenesis 1 | 29
Sparse scalp hair 1 | 42
Synophrys 1 | 40
Thin face 1 | 54
Thyroid cancer 1 | 36
Tracheitis 1 | 5

Tissue

Blood and immune system 30 | 16,909
Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678
Cardiovascular System 29 | 15,192

Target Family

Enzyme 23 | 4,145
Non-IDG 7 | 12,091

GO Process

tRNA modification 30 | 30
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable tRNA(His) guanylyltransferase THG1L Tbio Enzyme -0.60206 3.69 71
Alanine--tRNA ligase, cytoplasmic AARS Tbio Enzyme -2.49617 295.2 140
Alanine--tRNA ligase, mitochondrial AARS2 Tbio Enzyme -1.57311 34.3 75
tRNA modification GTPase GTPBP3, mitochondrial GTPBP3 Tbio Enzyme -0.76839 7.49 102
Putative methyltransferase NSUN6 NSUN6 Tbio Enzyme -0.36352 2.94 58
tRNA pseudouridine(38/39) synthase PUS3 Tbio Enzyme -1.22338 16.4 70
tRNA dimethylallyltransferase TRIT1 Tbio Enzyme -2.36135 237.3 69
tRNA (cytosine(38)-C(5))-methyltransferase TRDMT1 Tbio Enzyme -1.99628 94.9 337
Lupus La protein SSB Tbio Non-IDG -2.51632 289.3 331
Probable inactive tRNA-specific adenosine deaminase-like protein 3 ADAT3 Tdark Enzyme -1.40915 24.1 0