Development Level

Tbio 23 | 10,625
Tchem 12 | 1,890
Tdark 1 | 7,003

IMPC Phenotype

preweaning lethality, complete... 8 | 633
embryonic lethality prior to o... 4 | 148
embryonic lethality prior to t... 3 | 187
abnormal embryo size 2 | 112
increased circulating alkaline... 2 | 119
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal craniofacial morpholo... 1 | 12
abnormal cranium morphology 1 | 32
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal lung morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal spinal cord morpholog... 1 | 8
cataract 1 | 26
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 32
decreased circulating sodium l... 1 | 18
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
impaired glucose tolerance 1 | 52
increased circulating HDL chol... 1 | 63
increased erythrocyte cell num... 1 | 26
increased red blood cell distr... 1 | 21
increased thermal nociceptive ... 1 | 9

Disease

ovarian cancer 31 | 8,491
lung cancer 16 | 4,473
Multiple myeloma 14 | 1,327
psoriasis 14 | 6,685
medulloblastoma, large-cell 11 | 6,234
osteosarcoma 10 | 7,933
Neurodegenerative disease 9 | 383
glioblastoma 8 | 5,572
Cancer 7 | 2,346
Neuropathy 7 | 210
astrocytoma 7 | 1,493
diabetes mellitus 7 | 1,663
Charcot-Marie-Tooth disease 6 | 74
colon cancer 6 | 1,475
dermatomyositis 6 | 966
Breast cancer 5 | 3,098
Epilepsy 5 | 346
Myositis 5 | 24
Waldenstrons macroglobulinemia 5 | 764
juvenile dermatomyositis 5 | 1,189
non-small cell lung cancer 5 | 2,798
sonic hedgehog group medulloblastoma 5 | 1,482
Pick disease 4 | 1,893
acute quadriplegic myopathy 4 | 1,157
group 3 medulloblastoma 4 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
non primary Sjogren syndrome sicca 4 | 840
tuberculosis 4 | 1,563
Perrault syndrome 3 | 12
acute myeloid leukemia 3 | 785
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
invasive ductal carcinoma 3 | 2,950
lung adenocarcinoma 3 | 2,714
malignant mesothelioma 3 | 3,163
oligodendroglioma 3 | 2,849
pancreatic cancer 3 | 2,300
pediatric high grade glioma 3 | 2,712
primitive neuroectodermal tumor 3 | 3,031
Alpers syndrome 2 | 10
Carcinoma 2 | 2,147
Epidemic typhus 2 | 6
Gonadal dysgenesis XX type deafness 2 | 4
IGA Glomerulonephritis 2 | 454
Leigh disease 2 | 81
Leukodystrophy 2 | 30
Microcephaly 2 | 149
Mitochondrial encephalomyopathy 2 | 18
Obesity 2 | 616
Sleeping sickness 2 | 37
Subcutaneous panniculitis-like T-cell lymphoma 2 | 16
active Crohn's disease 2 | 918
adult high grade glioma 2 | 2,148
astrocytic glioma 2 | 2,241
atypical teratoid / rhabdoid tumor 2 | 4,369
breast carcinoma 2 | 1,614
chronic lymphocytic leukemia 2 | 244
ependymoma 2 | 2,514
hereditary spastic paraplegia 2 | 313
medulloblastoma 2 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
posterior fossa group B ependymoma 2 | 1,530
primary pancreatic ductal adenocarcinoma 2 | 1,271
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 3 months 2 | 327
tuberculosis and treatment for 6 months 2 | 686
Atypical autism 1 | 25
Basal ganglia calcification 1 | 17
Binder syndrome 1 | 3
Charcot-Marie-Tooth Disease, Axonal, Type 2D 1 | 1
Charcot-Marie-Tooth Disease, Dominant Intermediate C 1 | 1
Charcot-Marie-Tooth disease 2D 1 | 1
Charcot-Marie-Tooth disease, Type 2D 1 | 1
Charcot-Marie-Tooth disease, dominant, intermediate type, C 1 | 1
Combined oxidative phosphorylation deficiency 1 | 8
Distal hereditary motor neuronopathy type 5 1 | 2
Dyschromatosis symmetrica hereditaria 1 | 3
Endophthalmitis 1 | 10
Esophageal candidiasis 1 | 3
Glycine encephalopathy 1 | 28
Herpes zoster 1 | 7
Impetigo 1 | 9
Larsen syndrome 1 | 11
MITOCHONDRIAL MYOPATHY AND SIDEROBLASTIC ANEMIA 1 | 2
MYOPATHY, LACTIC ACIDOSIS, AND SIDEROBLASTIC ANEMIA 2 1 | 1
Methicillin-Resistant Staphylococcus Aureus Nasal Colonization 1 | 1
Mitochondrial myopathy 1 | 24
Myopathy with lactic acidosis and sideroblastic anemia 2 1 | 1
NEURONOPATHY, DISTAL HEREDITARY MOTOR, TYPE V 1 | 2
Neuronopathy, distal hereditary motor, 5A 1 | 2
Q fever 1 | 11
Retinal detachment 1 | 33
Rosacea 1 | 18
Scrapie 1 | 16
Staph Aureus Traumatic Skin Lesion Infection 1 | 1
Thymic dysplasia 1 | 2
Toxocariasis 1 | 6
Traumatic Skin Lesion Streptococcus Pyogenes Infection 1 | 1
Variant Creutzfeldt-Jakob disease 1 | 17
myopathy, lactic acidosis, and sideroblastic anemia 1 | 3

Tissue

Blood and immune system 36 | 17,994
Cardiovascular System 36 | 17,957
Digestive Tract 36 | 18,472
Endocrine System 36 | 18,511
Female tissues 36 | 18,646
Liver and Pancreas 36 | 18,135
Male tissues 36 | 17,968
Nervous System 36 | 18,560
Respiratory system 36 | 17,483
Skin and soft tissues 36 | 18,114
Urinary Tract 36 | 18,443

Target Family

Enzyme 34 | 4,146
Non-IDG 2 | 11,969

GO Process

tRNA aminoacylation for protei... 36 | 36
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
39S ribosomal protein L39, mitochondrial MRPL39 Tdark Non-IDG -0.45335 2.82 129
Eukaryotic translation elongation factor 1 epsilon-1 EEF1E1 Tbio Non-IDG -0.98788 11.7 130
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 AIMP2 Tbio Enzyme -1.29992 21.9 130
Arginine--tRNA ligase, cytoplasmic RARS Tchem Enzyme -3.05374 1058.7 140
Bifunctional glutamate/proline--tRNA ligase EPRS Tchem Enzyme -3.09040 1189.8 95
Aspartate--tRNA ligase, mitochondrial DARS2 Tbio Enzyme -1.62026 41.1 48
Phenylalanine--tRNA ligase, mitochondrial FARS2 Tchem Enzyme -2.02830 105.1 61
Inorganic pyrophosphatase 2, mitochondrial PPA2 Tbio Enzyme -1.34752 22.1 44
Tryptophan--tRNA ligase, cytoplasmic WARS Tbio Enzyme -2.71095 974.3 154
Probable arginine--tRNA ligase, mitochondrial RARS2 Tbio Enzyme -1.84710 68.4 27