Development Level

Tbio 8 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
increased lean body mass 2 | 172
abnormal testis morphology 1 | 43
decreased lean body mass 1 | 135
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 8 | 11,493
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
Astrocytoma, Pilocytic 6 | 3,081
astrocytic glioma 6 | 2,597
ependymoma 6 | 4,679
oligodendroglioma 6 | 2,850
ovarian cancer 6 | 8,520
Kidney cancer 5 | 2,613
adult high grade glioma 5 | 3,801
lung carcinoma 5 | 2,843
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
Pick disease 4 | 1,894
group 3 medulloblastoma 4 | 4,104
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
Intellectual disability 3 | 1,016
Parkinson's disease 3 | 392
Schizophrenia 3 | 1,160
psoriasis 3 | 6,694
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Cerebellar Ataxia 2 | 304
Cognitive delay 2 | 608
Depressive disorder 2 | 409
Down syndrome 2 | 499
Dull intelligence 2 | 645
Dysarthria 2 | 192
Fatigue 2 | 182
Global developmental delay 2 | 608
Liver Cirrhosis, Experimental 2 | 769
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Poor school performance 2 | 645
Reflex, Deep Tendon, Absent 2 | 92
Tetanus 2 | 68
acute quadriplegic myopathy 2 | 1,158
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
non-small cell lung cancer 2 | 2,890
Acquired metabolic disease 1 | 336
Akinesia 1 | 13
Angiodysplasia 1 | 5
Anxiety 1 | 136
Anxiety disease 1 | 113
Blepharoptosis 1 | 231
Botulism 1 | 24
Brain disease 1 | 96
Chemical and Drug Induced Liver Injury 1 | 195
Childhood medulloblastoma 1 | 4
Congenital myasthenic syndrome 1 | 25
Convex nasal bridge 1 | 57
Cyclothymic disorder 1 | 8
Degenerative brain disorder 1 | 100
Diabetes Mellitus, Experimental 1 | 108
Downward slant of palpebral fissure 1 | 158
Dyspnea 1 | 76
Frontotemporal dementia 1 | 51
Gaucher disease type 1 1 | 180
Generalized muscle weakness 1 | 57
Griscelli syndrome type 2 1 | 12
Hypomyelinating leukodystrophy 6 1 | 26
Ichthyoses 1 | 41
Ichthyosis 1 | 56
L-2-hydroxyglutaric aciduria 1 | 8
Mood swings 1 | 77
Muscle Rigidity 1 | 49
Muscle Weakness 1 | 170
Nerve Degeneration 1 | 121
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Oculocerebrorenal syndrome 1 | 29
Palmoplantar keratosis 1 | 74
Paralysed 1 | 42
Parkinsonian Disorders 1 | 56
Peripheral Neuropathy 1 | 134
Pineoblastoma 1 | 6
Prenatal onset 1 | 139
Progressive mental retardation 1 | 37
Prominent nasal bridge 1 | 57
Reduced fetal movement 1 | 51
Respiratory Failure 1 | 104
Respiratory Insufficiency 1 | 132
Respiratory function loss 1 | 121
Resting Tremor 1 | 9
Sensorineural Hearing Loss (disorder) 1 | 284
Tremor 1 | 113
Velocardiofacial syndrome 1 | 46
Vici syndrome 1 | 14
Voice Fatigue 1 | 7

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192

Target Family

Non-IDG 9 | 12,091

GO Process

synaptic vesicle priming 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium-dependent secretion activator 2 CADPS2 Tbio Non-IDG -1.18033 15.0 36
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.76329 62.0 93
Protein unc-13 homolog A UNC13A Tbio Non-IDG -1.84052 68.3 23
Synaptosomal-associated protein 47 SNAP47 Tdark Non-IDG -1.20232 16.2 34
Synaptosomal-associated protein 29 SNAP29 Tbio Non-IDG -1.47467 28.0 125
Calcium-dependent secretion activator 1 CADPS Tbio Non-IDG -1.29344 23.2 103
Synaptosomal-associated protein 25 SNAP25 Tbio Non-IDG -2.61491 385.0 821
Synaptosomal-associated protein 23 SNAP23 Tbio Non-IDG -2.11951 135.0 292
Protein unc-13 homolog B UNC13B Tbio Non-IDG -2.08635 111.4 161