Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
convulsive seizures 1 | 13
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased total body fat amoun... 1 | 207
hemorrhage 1 | 23
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
tremors 1 | 39

Disease

Astrocytoma, Pilocytic 7 | 3,081
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
Carcinoma 6 | 11,493
adult high grade glioma 6 | 3,801
astrocytic glioma 5 | 2,597
lung carcinoma 5 | 2,843
medulloblastoma, large-cell 5 | 6,241
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
Intellectual disability 4 | 1,016
Pick disease 4 | 1,894
group 3 medulloblastoma 4 | 4,104
psoriasis 4 | 6,694
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 658
Dementia 3 | 175
Schizophrenia 3 | 1,160
ovarian cancer 3 | 8,520
Amyotrophic lateral sclerosis 2 | 451
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cerebrovascular disease 2 | 238
Depressive disorder 2 | 409
Epilepsy 2 | 792
Neurodevelopmental Disorders 2 | 70
Toxic encephalopathy 2 | 141
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
osteosarcoma 2 | 7,950
Adrenal cortical adenoma 1 | 19
Anxiety 1 | 136
Anxiety disease 1 | 113
Autism Spectrum Disorders 1 | 75
Autoimmune thyroiditis 1 | 27
Brain disease 1 | 96
CEROID LIPOFUSCINOSIS, NEURONAL, 6 1 | 6
Carcinoma, Non-Small-Cell Lung 1 | 107
Chronic tic disorder 1 | 8
Degenerative brain disorder 1 | 100
Dyspnea 1 | 76
Early infantile epileptic encephalopathy with suppression bursts 1 | 10
Early myoclonic encephalopathy 1 | 15
Epilepsies, Myoclonic 1 | 32
Epileptic encephalopathy 1 | 26
Fatigue 1 | 182
Febrile Convulsions 1 | 14
Fragile X syndrome 1 | 34
Frontotemporal dementia 1 | 51
Gaucher disease type 1 1 | 180
Generalized muscle weakness 1 | 57
Generalized myoclonic seizures 1 | 30
Global developmental delay, severe 1 | 47
Griscelli syndrome 1 | 24
Hemangioma 1 | 69
Hermansky-Pudlak syndrome 1 | 42
Highly variable severity 1 | 157
Hypomyelinating leukodystrophy 6 1 | 26
Hypsarrhythmia 1 | 25
Leukemia, Acute Myeloid 1 | 17
Leukemia, Myelocytic, Acute 1 | 120
Memory Disorders 1 | 40
Mood swings 1 | 77
Muscle Cramp 1 | 55
Myoclonic Epilepsies, Progressive 1 | 44
Neonatal onset 1 | 21
Nerve Degeneration 1 | 121
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Obstructive jaundice 1 | 7
Ornithosis 1 | 9
Pain 1 | 103
Papilloma 1 | 44
Paralysed 1 | 42
Photosensitivity of skin 1 | 51
Platelet storage pool deficiency 1 | 21
Polyhydramnios 1 | 108
Respiratory Failure 1 | 104
Severe psychomotor retardation 1 | 47
Skeletal muscle atrophy 1 | 139
Spastic Paraplegia 1 | 42
Spastic Quadriplegia 1 | 42
Supratentorial atrophy 1 | 94
Tonic - clonic seizures 1 | 44
Tremor 1 | 113
Variable expressivity 1 | 157
Warburg micro syndrome 1 | 18
West Syndrome 1 | 28
Williams Syndrome 1 | 10
X-linked dominant 1 | 57
acute T cell leukemia 1 | 17
muscle degeneration 1 | 139
non-small cell lung carcinoma 1 | 317
non-syndromic X-linked intellectual disability 1 | 20

Tissue

Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Cardiovascular System 7 | 15,192

Target Family

Non-IDG 6 | 12,091
Enzyme 2 | 4,145

GO Process

synaptic vesicle maturation 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein unc-13 homolog A UNC13A Tbio Non-IDG -1.84052 68.3 23
SNARE-associated protein Snapin SNAPIN Tbio Non-IDG -1.65821 50.9 69
Palmitoyltransferase ZDHHC15 ZDHHC15 Tdark Enzyme -0.26151 1.71 55
Phosphatidylinositol-binding clathrin assembly protein PICALM Tbio Non-IDG -1.92862 84.7 130
Disks large homolog 4 DLG4 Tchem Non-IDG -2.98766 883.9 559
Syntaxin-binding protein 1 STXBP1 Tbio Non-IDG -2.30714 221.0 351
Synaptophysin SYP Tbio Non-IDG -3.49425 2821.7 952
Ras-related protein Rab-3A RAB3A Tbio Enzyme -2.29258 206.6 236