Development Level

Tbio 14 | 11,445
Tchem 3 | 1,598
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal testis morphology 1 | 43
cataract 1 | 92
convulsive seizures 1 | 13
decreased circulating glycerol... 1 | 16
edema 1 | 59
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Astrocytoma, Pilocytic 13 | 3,081
ependymoma 13 | 4,679
glioblastoma 13 | 5,792
adult high grade glioma 12 | 3,801
astrocytic glioma 12 | 2,597
atypical teratoid / rhabdoid tumor 12 | 5,112
medulloblastoma, large-cell 12 | 6,241
group 3 medulloblastoma 11 | 4,104
oligodendroglioma 11 | 2,850
Pick disease 10 | 1,894
Carcinoma 9 | 11,493
primitive neuroectodermal tumor 9 | 3,035
lung carcinoma 8 | 2,843
subependymal giant cell astrocytoma 8 | 2,287
Kidney cancer 7 | 2,613
psoriasis 7 | 6,694
Bipolar Disorder 6 | 666
Depressive disorder 6 | 409
malignant mesothelioma 6 | 3,232
Mental Depression 5 | 333
Schizophrenia 5 | 1,160
lung cancer 5 | 4,740
osteosarcoma 5 | 7,950
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
Neurodegenerative disease 4 | 414
Parkinson's disease 4 | 392
interstitial cystitis 4 | 2,312
ovarian cancer 4 | 8,520
Alzheimer's disease 3 | 658
Epilepsy 3 | 792
Liver cancer 3 | 604
Major Depressive Disorder 3 | 301
Prenatal onset 3 | 139
Psychotic Disorders 3 | 151
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Amyotrophic lateral sclerosis 2 | 451
Arthrogryposis 2 | 54
Blepharoptosis 2 | 231
Botulism 2 | 24
Brain disease 2 | 96
Cancer 2 | 2,499
Cerebellar Hypoplasia 2 | 61
Chubby cheeks 2 | 50
Cocaine Dependence 2 | 51
Deafness 2 | 198
Downturned corners of mouth 2 | 48
Exophthalmos 2 | 112
Full cheeks 2 | 50
Hyperplasia of cheeks 2 | 50
Hypertrophy of cheeks 2 | 50
Hypoplastic mandible condyle 2 | 275
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Muscle Spasticity 2 | 195
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Puffy cheeks 2 | 50
Reduced fetal movement 2 | 51
Reflex, Deep Tendon, Absent 2 | 92
Respiratory Insufficiency 2 | 132
Respiratory function loss 2 | 121
Seizures 2 | 596
Short stature 2 | 531
Skeletal muscle atrophy 2 | 139
Small head 2 | 374
Tetanus 2 | 68
Unipolar Depression 2 | 250
Wernicke encephalopathy 2 | 12
atypical teratoid/rhabdoid tumor 2 | 357
colon cancer 2 | 1,478
facioscapulohumeral dystrophy 2 | 288
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
invasive ductal carcinoma 2 | 2,951
medulloblastoma 2 | 720
muscle degeneration 2 | 139
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010
Agyria 1 | 15
Auricular malformation 1 | 41
Fused vertebrae 1 | 25
Hyperkyphosis 1 | 111
Kyphosis deformity of spine 1 | 114
Metatarsus Varus 1 | 24
Pain 1 | 103
Progressive microcephaly 1 | 32
Spinal fusion 1 | 25
Underweight 1 | 17
Vertebral body fusion 1 | 25
Weight less than 3rd percentile 1 | 17
Wolf-Hirschhorn syndrome 1 | 32

Tissue

Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Urinary Tract 17 | 16,678
Blood and immune system 16 | 16,909
Cardiovascular System 15 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634
Ion Channel 1 | 344

GO Process

synaptic vesicle exocytosis 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Otoferlin OTOF Tbio Non-IDG -2.05743 118.7 45
Protein piccolo PCLO Tbio Non-IDG -2.48756 308.4 124
Protein unc-13 homolog A UNC13A Tbio Non-IDG -1.84052 68.3 23
Protein unc-13 homolog C UNC13C Tdark Non-IDG -0.85788 5.65 19
SNARE-associated protein Snapin SNAPIN Tbio Non-IDG -1.65821 50.9 69
DnaJ homolog subfamily C member 5 DNAJC5 Tbio Non-IDG -1.98508 92.5 193
E3 ubiquitin-protein ligase TRIM9 TRIM9 Tbio Enzyme -1.03221 10.8 307
P2X purinoceptor 7 P2RX7 Tchem Ion Channel -2.96940 962.2 272
Regulating synaptic membrane exocytosis protein 1 RIMS1 Tbio Non-IDG -1.95711 85.7 11
Complexin-3 CPLX3 Tbio Non-IDG -1.42416 26.8 91