Development Level

Tbio 38 | 11,651
Tdark 19 | 6,593
Tchem 4 | 1,388
Tclin 3 | 612

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

decreased circulating choleste... 3 | 93
decreased grip strength 3 | 116
decreased lean body mass 3 | 135
increased circulating alkaline... 3 | 122
short tibia 3 | 97
tremors 3 | 39
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
abnormal locomotor behavior 2 | 24
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased fasted circulating g... 2 | 65
decreased lymphocyte cell numb... 2 | 83
decreased pulmonary respirator... 2 | 5
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
enlarged heart 2 | 210
enlarged stomach 2 | 2
impaired glucose tolerance 2 | 75
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
increased red blood cell distr... 2 | 34
increased total body fat amoun... 2 | 134
preweaning lethality, complete... 2 | 979
small thymus 2 | 16
abnormal behavior 1 | 298
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased circulating amylase ... 1 | 28
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased circulating insulin ... 1 | 3
increased fasted circulating g... 1 | 76
limb grasping 1 | 41
polycystic kidney 1 | 15
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 55 | 11,493
lung carcinoma 39 | 2,843
Kidney cancer 38 | 2,613
medulloblastoma, large-cell 37 | 6,241
atypical teratoid / rhabdoid tumor 35 | 5,112
glioblastoma 29 | 5,792
ovarian cancer 29 | 8,520
adult high grade glioma 28 | 3,801
lung cancer 27 | 4,740
oligodendroglioma 27 | 2,850
ependymoma 26 | 4,679
Astrocytoma, Pilocytic 25 | 3,081
osteosarcoma 24 | 7,950
Breast cancer 23 | 3,578
group 3 medulloblastoma 21 | 4,104
group 4 medulloblastoma 21 | 1,855
primitive neuroectodermal tumor 21 | 3,035
psoriasis 20 | 6,694
Schizophrenia 18 | 1,160
interstitial cystitis 17 | 2,312
Autistic Disorder 15 | 364
lung adenocarcinoma 15 | 2,716
subependymal giant cell astrocytoma 15 | 2,287
Bipolar Disorder 14 | 666
astrocytic glioma 14 | 2,597
malignant mesothelioma 14 | 3,232
Liver cancer 13 | 604
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
invasive ductal carcinoma 13 | 2,951
pituitary cancer 13 | 1,972
Intellectual disability 12 | 1,016
non-small cell lung cancer 12 | 2,890
astrocytoma 11 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
Autism spectrum disorder 10 | 101
Alzheimer's disease 9 | 658
Pick disease 9 | 1,894
pancreatic cancer 9 | 2,398
ulcerative colitis 9 | 1,819
Depressive disorder 8 | 409
Parkinson's disease 8 | 392
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Autosomal recessive predisposition 7 | 1,442
Cancer 7 | 2,499
Endometrial cancer 7 | 311
Epilepsy 7 | 792
Mental Depression 7 | 333
Obesity 7 | 678
Seizures 7 | 596
Melanoma 6 | 711
colon cancer 6 | 1,478
ductal carcinoma in situ 6 | 1,745
medulloblastoma 6 | 720
tuberculosis 6 | 2,010
Amphetamine-Related Disorders 5 | 74
Autism Spectrum Disorders 5 | 75
Brain disease 5 | 96
Breast Neoplasms 5 | 445
Cognitive delay 5 | 608
Dementia 5 | 175
Global developmental delay 5 | 608
Hypoplastic mandible condyle 5 | 275
Mammary Neoplasms 5 | 425
Mandibular hypoplasia 5 | 275
Mental and motor retardation 5 | 608
Micrognathism 5 | 275
Movement Disorders 5 | 55
Muscle hypotonia 5 | 571
adrenocortical carcinoma 5 | 1,428
posterior fossa group A ependymoma 5 | 468
Acquired scoliosis 4 | 281
Alcoholic Intoxication, Chronic 4 | 289
Attention deficit hyperactivity disorder 4 | 278
Byzanthine arch palate 4 | 194
Cerebellar Ataxia 4 | 304
Cocaine-Related Disorders 4 | 92
Concave bridge of nose 4 | 195
Constipation 4 | 181
Curvature of spine 4 | 282
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Dull intelligence 4 | 645
Gastroesophageal reflux disease 4 | 110
Large intestine cancer 4 | 126
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Neurodegenerative disease 4 | 414
Parkinson Disease 4 | 64
Poor school performance 4 | 645
Short stature 4 | 531
Skin cancer 4 | 469
Small head 4 | 374
Substance-Related Disorders 4 | 115
Toxic encephalopathy 4 | 141
breast carcinoma 4 | 1,638
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
nasopharyngeal carcinoma 4 | 1,058
spina bifida 4 | 1,074

Tissue

Endocrine System 61 | 18,159
Female tissues 60 | 17,400
Male tissues 59 | 17,142
Nervous System 59 | 16,725
Blood and immune system 58 | 16,909
Digestive Tract 58 | 17,369
Liver and Pancreas 58 | 16,750
Skin and soft tissues 58 | 17,230
Respiratory system 57 | 16,393
Urinary Tract 56 | 16,678
Cardiovascular System 55 | 15,192

Target Family

Non-IDG 48 | 12,091
Enzyme 7 | 4,145
GPCR 5 | 408
Kinase 2 | 634
Transcription Factor 2 | 1,400

GO Process

synapse assembly 64 | 64
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Drebrin-like protein DBNL Tbio Non-IDG -1.16567 21.1 172
Protocadherin beta-1 PCDHB1 Tdark Non-IDG 0.41 0.32 73
Protocadherin beta-11 PCDHB11 Tdark Non-IDG 0.78 0.14 108
Protocadherin beta-3 PCDHB3 Tdark Non-IDG -0.19592 0.49 89
Protocadherin beta-7 PCDHB7 Tdark Non-IDG 0.10 0.78 39
Protocadherin beta-5 PCDHB5 Tdark Non-IDG 0.20 0.41 87
D(2) dopamine receptor DRD2 Tclin GPCR -3.28700 1882.2 264
Cyclin-dependent-like kinase 5 CDK5 Tchem Kinase -3.06393 1238.4 694
Neuroligin-3 NLGN3 Tbio Enzyme -1.86262 71.5 179
SH3 and multiple ankyrin repeat domains protein 3 SHANK3 Tbio Non-IDG -2.26648 182.9 0