Development Level

Tbio 14 | 11,445
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased lactate dehydrogenas... 1 | 16

Disease

psoriasis 11 | 6,694
Carcinoma 10 | 11,493
osteosarcoma 10 | 7,950
glioblastoma 8 | 5,792
lung cancer 8 | 4,740
Cancer 7 | 2,499
medulloblastoma, large-cell 7 | 6,241
Breast cancer 6 | 3,578
Low set ears 6 | 181
ovarian cancer 6 | 8,520
Downward slant of palpebral fissure 5 | 158
Dull intelligence 5 | 645
Intellectual disability 5 | 1,016
Kidney cancer 5 | 2,613
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Posteriorly rotated ear 5 | 61
Schizophrenia 5 | 1,160
ductal carcinoma in situ 5 | 1,745
malignant mesothelioma 5 | 3,232
oligodendroglioma 5 | 2,850
Cardiovascular Abnormalities 4 | 31
Cardiovascular Diseases 4 | 59
Concave bridge of nose 4 | 195
Congenital central hypoventilation syndrome 4 | 18
Cryptorchidism 4 | 296
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Strabismus 4 | 270
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
atypical teratoid / rhabdoid tumor 4 | 5,112
breast carcinoma 4 | 1,638
ependymoma 4 | 4,679
primitive neuroectodermal tumor 4 | 3,035
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Astrocytoma, Pilocytic 3 | 3,081
Autonomic nervous system disorders 3 | 19
Bipolar Disorder 3 | 666
Blepharoptosis 3 | 231
Body Temperature Changes 3 | 10
Bushy eyebrows 3 | 49
Central hypoventilation 3 | 8
Cognitive delay 3 | 608
Congenital central hypoventilation 3 | 6
Constipation 3 | 181
Dysautonomia 3 | 20
Dyschezia 3 | 135
Epilepsy 3 | 792
Feeding difficulties 3 | 127
Ganglioneuroblastoma 3 | 11
Ganglioneuroma 3 | 13
Glioma 3 | 74
Global developmental delay 3 | 608
Hirschsprung Disease 3 | 31
Hirschsprung's disease 3 | 46
Hyperhidrosis disorder 3 | 81
Hypotrophic malar bone 3 | 129
Increased sweating 3 | 81
Malar flattening 3 | 129
Megacolon 3 | 29
Mental and motor retardation 3 | 608
Mouth Abnormalities 3 | 14
Muscle hypotonia 3 | 571
Poor temperature regulation 3 | 10
Seizures 3 | 596
Short stature 3 | 531
Sweating 3 | 81
atypical teratoid/rhabdoid tumor 3 | 357
colon cancer 3 | 1,478
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
Acquired scoliosis 2 | 281
Adenoid Cystic Carcinoma 2 | 99
Broad flat nasal bridge 2 | 236
Carcinoma, Adenoid Cystic 2 | 99
Curvature of spine 2 | 282
Failure to gain weight 2 | 365
Gastroesophageal reflux disease 2 | 110
Heartburn 2 | 78
Liver cancer 2 | 604
Low Birth Weights 2 | 69
Major Depressive Disorder 2 | 301
Melanoma 2 | 711
Nasal bridge wide 2 | 236
Neuroblastoma 2 | 80
Neuropathy 2 | 261
Pediatric failure to thrive 2 | 365
RENAL ADYSPLASIA 2 | 25
Renal dysplasia 2 | 28
Respiratory Insufficiency 2 | 132
Skin cancer 2 | 469
Toxic encephalopathy 2 | 141

Tissue

Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Skin and soft tissues 15 | 17,230
Female tissues 14 | 17,400
Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Liver and Pancreas 12 | 16,750
Urinary Tract 12 | 16,678

Target Family

Transcription Factor 9 | 1,400
Non-IDG 5 | 12,091
Kinase 1 | 634

GO Process

sympathetic nervous system dev... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.44791 277.6 405
Neurofibromin NF1 Tbio Non-IDG -3.60161 4054.2 355
Paired mesoderm homeobox protein 2A PHOX2A Tbio Transcription Factor -1.75209 58.7 143
Transcription factor SOX-4 SOX4 Tbio Transcription Factor -2.22104 164.2 211
Transcription factor SOX-11 SOX11 Tbio Transcription Factor -2.01545 106.1 219
Semaphorin-3A SEMA3A Tbio Non-IDG -2.70786 548.1 185
Paired mesoderm homeobox protein 2B PHOX2B Tbio Transcription Factor -2.49193 315.4 127
Heart- and neural crest derivatives-expressed protein 2 HAND2 Tbio Transcription Factor -2.99854 926.7 220
Tumor protein 63 TP63 Tbio Transcription Factor -3.07398 1154.1 448