Development Level

Tbio 8 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

abnormal lens morphology 1 | 81
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased lean body mass 1 | 172
increased spleen weight 1 | 10
persistence of hyaloid vascula... 1 | 33
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Hypertension 9 | 396
Atherosclerosis 8 | 291
diabetes mellitus 8 | 1,728
Carcinoma 7 | 11,493
Kidney disease 7 | 430
osteosarcoma 7 | 7,950
ovarian cancer 6 | 8,520
Cancer 5 | 2,499
Chronic granulomatous disease 5 | 13
Diabetes Mellitus, Experimental 5 | 108
Heart failure 5 | 162
Hypertensive disease 5 | 292
glioblastoma 5 | 5,792
interstitial cystitis 5 | 2,312
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Cerebrovascular disease 4 | 238
Kidney Failure, Chronic 4 | 46
Liver Cirrhosis, Experimental 4 | 769
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
pancreatic cancer 4 | 2,398
Absence of bactericidal oxidative 'respiratory burst' in phagocytes 3 | 3
Cell Transformation, Neoplastic 3 | 97
Cellulitis due to immunodeficiency 3 | 3
Chronic Obstructive Airway Disease 3 | 37
Coronary artery disease 3 | 268
Decreased activity of NADPH oxidase 3 | 3
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Eczema 3 | 45
Escherichia coli Infections 3 | 4
Fever 3 | 138
Granulomatosis 3 | 7
Heart disease 3 | 306
Hepatic abscesses due to immunodeficiency 3 | 3
Hepatomegaly 3 | 285
Hypercholesterolemia 3 | 44
Hyperpigmented macules 3 | 42
Infectious disease of lung 3 | 29
Lupus Erythematosus, Discoid 3 | 4
Lymphadenitis 3 | 15
Lymphadenopathy 3 | 62
Malabsorption 3 | 82
Mediastinal lymphadenopathy 3 | 10
Multiple pulmonary infections 3 | 29
Negative nitroblue tetrazolium reduction test 3 | 3
Neoplastic Cell Transformation 3 | 89
Neutrophil abnormality 3 | 20
Osteomyelitis due to immunodeficiency 3 | 4
Otitis Media 3 | 52
Paranasal Sinus Diseases 3 | 34
Perirectal abscess 3 | 5
Photosensitivity of skin 3 | 51
Pulmonary Fibrosis 3 | 106
Pyloric Stenosis 3 | 47
Rectal abscess 3 | 5
Recurrent Aspergillus infections 3 | 3
Recurrent Burkholderia cepacia infections 3 | 3
Recurrent Klebsiella infections 3 | 3
Recurrent Serratia marcescens infections 3 | 3
Recurrent Staphylococcus aureus infections 3 | 4
Recurrent bacterial skin infections 3 | 8
Recurrent pneumonia 3 | 29
Recurrent pulmonary infections 3 | 29
Recurrent respiratory infections 3 | 141
Renal Insufficiency 3 | 90
Reperfusion Injury 3 | 86
Sinusitis 3 | 65
Splenomegaly 3 | 190
Tracheoesophageal Fistula 3 | 36
adult high grade glioma 3 | 3,801
cutaneous lupus erythematosus 3 | 1,057
ependymoma 3 | 4,679
esophageal adenocarcinoma 3 | 737
medulloblastoma, large-cell 3 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
psoriasis 3 | 6,694
ulcerative colitis 3 | 1,819
Arthritis, Rheumatoid 2 | 174
Bipolar Disorder 2 | 666
Breast cancer 2 | 3,578
Cerebrovascular accident 2 | 63
Colonic Neoplasms 2 | 142
Hyperalgesia 2 | 83
Liver Cirrhosis 2 | 181
Neurodegenerative disease 2 | 414
Parkinson Disease 2 | 64
Proteinuria 2 | 144
Schizophrenia 2 | 1,160
Stroke 2 | 33
Toxic encephalopathy 2 | 141
adrenocortical carcinoma 2 | 1,428
cystic fibrosis 2 | 1,696
mucosa-associated lymphoid tissue lymphoma 2 | 484
primary Sjogren syndrome 2 | 735
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 12 | 16,909
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Skin and soft tissues 12 | 17,230
Digestive Tract 11 | 17,369
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Urinary Tract 11 | 16,678
Respiratory system 10 | 16,393
Cardiovascular System 9 | 15,192

Target Family

Enzyme 7 | 4,145
Non-IDG 5 | 12,091
Ion Channel 1 | 344

GO Process

superoxide anion generation 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b-245 heavy chain CYBB Tchem Ion Channel -3.09698 1276.8 315
Arachidonate 12-lipoxygenase, 12S-type ALOX12 Tchem Enzyme -2.35458 223.8 137
Dual oxidase 1 DUOX1 Tbio Enzyme -2.50131 279.5 85
NADPH oxidase 3 NOX3 Tbio Enzyme -1.52922 32.9 139
NADPH oxidase 5 NOX5 Tchem Enzyme -1.82693 76.8 174
Proteoglycan 3 PRG3 Tbio Non-IDG -1.00718 11.4 37
NADPH oxidase 1 NOX1 Tchem Enzyme -2.59188 397.6 233
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.58058 376.0 164
Neutrophil cytosol factor 1 NCF1 Tbio Non-IDG -2.58838 554.8 675
Superoxide dismutase [Cu-Zn] SOD1 Tbio Enzyme -3.30643 1972.1 1103