Development Level

Tbio 29 | 11,651
Tchem 11 | 1,388
Tclin 2 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to t... 5 | 278
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
enlarged heart 3 | 210
abnormal embryo size 2 | 220
decreased circulating HDL chol... 2 | 68
decreased circulating insulin ... 2 | 76
decreased lactate dehydrogenas... 2 | 16
decreased spleen weight 2 | 10
decreased vertical activity 2 | 208
increased lean body mass 2 | 172
preweaning lethality, incomple... 2 | 499
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal tail movements 1 | 12
anophthalmia 1 | 33
cataract 1 | 92
cleft palate 1 | 8
convulsive seizures 1 | 13
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased startle reflex 1 | 75
dilated heart left ventricle 1 | 11
enlarged kidney 1 | 14
enlarged spleen 1 | 41
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac stroke volum... 1 | 1
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97

Disease

Carcinoma 26 | 11,493
ovarian cancer 26 | 8,520
osteosarcoma 21 | 7,950
glioblastoma 20 | 5,792
medulloblastoma, large-cell 20 | 6,241
atypical teratoid / rhabdoid tumor 18 | 5,112
psoriasis 18 | 6,694
ependymoma 17 | 4,679
group 3 medulloblastoma 14 | 4,104
Breast cancer 13 | 3,578
adult high grade glioma 13 | 3,801
lung cancer 13 | 4,740
oligodendroglioma 13 | 2,850
Multiple myeloma 12 | 1,332
subependymal giant cell astrocytoma 12 | 2,287
Astrocytoma, Pilocytic 11 | 3,081
Schizophrenia 11 | 1,160
Cancer 10 | 2,499
Pick disease 10 | 1,894
astrocytic glioma 10 | 2,597
invasive ductal carcinoma 10 | 2,951
primitive neuroectodermal tumor 10 | 3,035
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Bipolar Disorder 7 | 666
Down syndrome 7 | 499
Intellectual disability 7 | 1,016
Rheumatoid arthritis 7 | 1,191
Waldenstrons macroglobulinemia 7 | 765
acute quadriplegic myopathy 7 | 1,158
group 4 medulloblastoma 7 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
pancreatic cancer 7 | 2,398
tuberculosis 7 | 2,010
Alzheimer's disease 6 | 658
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Muscle hypotonia 6 | 571
astrocytoma 6 | 1,146
colon cancer 6 | 1,478
dermatomyositis 6 | 966
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
lung carcinoma 6 | 2,843
ulcerative colitis 6 | 1,819
Duchenne muscular dystrophy 5 | 601
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Multiple Sclerosis 5 | 540
Neurodegenerative disease 5 | 414
Poor school performance 5 | 645
juvenile dermatomyositis 5 | 1,187
primary pancreatic ductal adenocarcinoma 5 | 1,109
Autosomal recessive predisposition 4 | 1,442
Epilepsy 4 | 792
Kidney disease 4 | 430
Optic Atrophy 4 | 242
Seizures 4 | 596
active Crohn's disease 4 | 922
breast carcinoma 4 | 1,638
cutaneous lupus erythematosus 4 | 1,057
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
malignant mesothelioma 4 | 3,232
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
progressive supranuclear palsy 4 | 676
Animal Mammary Neoplasms 3 | 136
Babinski Reflex 3 | 100
Blepharoptosis 3 | 231
Cerebellar Ataxia 3 | 304
Dystonia 3 | 164
Eye disease 3 | 62
Failure to gain weight 3 | 365
Impaired exercise tolerance 3 | 42
Increased serum lactate 3 | 60
Major Depressive Disorder 3 | 301
Mammary Neoplasms, Animal 3 | 136
Mammary Neoplasms, Experimental 3 | 154
Metachromatic leukodystrophy 3 | 14
Mood Disorders 3 | 184
Myocardial Infarction 3 | 151
Neuropathy 3 | 261
Nystagmus 3 | 317
Parkinson's disease 3 | 392
Pediatric failure to thrive 3 | 365
Sensorineural Hearing Loss (disorder) 3 | 284
Toxic encephalopathy 3 | 141
Unipolar Depression 3 | 250
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
ductal carcinoma in situ 3 | 1,745
hereditary spastic paraplegia 3 | 318
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung cancer 3 | 2,890
pancreatic carcinoma 3 | 562

Tissue

Endocrine System 42 | 18,159
Male tissues 42 | 17,142
Blood and immune system 41 | 16,909
Digestive Tract 41 | 17,369
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Nervous System 41 | 16,725
Respiratory system 41 | 16,393
Skin and soft tissues 41 | 17,230
Urinary Tract 41 | 16,678
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 23 | 12,091
Enzyme 14 | 4,145
Kinase 2 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

GO Process

substantia nigra development 42 | 42
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein NDRG2 NDRG2 Tbio Non-IDG -1.94343 142.1 289
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.77874 581.3 185
Caspase-5 CASP5 Tchem Enzyme -2.01445 96.1 427
Cytochrome c oxidase subunit 6B1 COX6B1 Tbio Enzyme -1.29185 18.7 218
ATP synthase F(0) complex subunit B1, mitochondrial ATP5PB Tbio Enzyme -0.79382 5.36 113
Myelin proteolipid protein PLP1 Tbio Non-IDG -2.78813 591.1 191
Transforming protein RhoA RHOA Tbio Enzyme -3.54095 3332.7 501
Zinc finger protein 148 ZNF148 Tbio Transcription Factor -1.77339 65.4 193
14-3-3 protein epsilon YWHAE Tbio Non-IDG -2.23108 170.5 348
Creatine kinase B-type CKB Tbio Kinase -2.09121 122.4 465