Development Level

Tbio 27 | 10,625
Tchem 13 | 1,890
Tclin 3 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 6 | 633
decreased circulating insulin ... 3 | 75
decreased total body fat amoun... 3 | 186
embryonic lethality prior to t... 3 | 187
abnormal embryo size 2 | 112
decreased lactate dehydrogenas... 2 | 14
increased circulating choleste... 2 | 53
increased lean body mass 2 | 107
increased or absent threshold ... 2 | 128
abnormal behavioral response t... 1 | 52
abnormal body wall morphology 1 | 7
abnormal bone structure 1 | 131
abnormal motor learning 1 | 4
abnormal retinal vasculature m... 1 | 15
abnormal sleep behavior 1 | 63
abnormal tail movements 1 | 12
abnormal whole-body plethysmog... 1 | 4
cataract 1 | 26
cleft palate 1 | 6
convulsive seizures 1 | 11
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating bilirubi... 1 | 14
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased erythrocyte cell num... 1 | 43
decreased lean body mass 1 | 195
decreased pulmonary respirator... 1 | 4
decreased startle reflex 1 | 48
decreased total retina thickne... 1 | 20
dilated heart left ventricle 1 | 10
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
hyperactivity 1 | 108
immune system phenotype 1 | 17
increased bone mineral density 1 | 52
increased cardiac stroke volum... 1 | 1
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased heart weight 1 | 37
increased startle reflex 1 | 38
increased tidal volume 1 | 1
increased total body fat amoun... 1 | 57
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
tremors 1 | 34

Disease

ovarian cancer 27 | 8,484
osteosarcoma 22 | 7,933
medulloblastoma, large-cell 21 | 6,234
glioblastoma 19 | 5,572
psoriasis 19 | 6,685
lung cancer 14 | 4,466
oligodendroglioma 14 | 2,849
Breast cancer 13 | 3,094
Multiple myeloma 13 | 1,327
subependymal giant cell astrocytoma 13 | 2,287
atypical teratoid / rhabdoid tumor 12 | 4,369
pilocytic astrocytoma 12 | 3,086
Pick disease 11 | 1,893
ependymoma 11 | 2,514
pediatric high grade glioma 11 | 2,712
primitive neuroectodermal tumor 11 | 3,031
Cancer 10 | 2,346
astrocytoma 10 | 1,493
invasive ductal carcinoma 10 | 2,950
atypical teratoid/rhabdoid tumor 9 | 1,095
Rheumatoid Arthritis 8 | 1,160
Waldenstrons macroglobulinemia 8 | 765
acute quadriplegic myopathy 8 | 1,157
adult high grade glioma 8 | 2,148
astrocytic glioma 8 | 2,241
group 3 medulloblastoma 8 | 2,254
pancreatic cancer 8 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
ulcerative colitis 8 | 2,087
Down syndrome 7 | 548
colon cancer 7 | 1,475
group 4 medulloblastoma 7 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
lung adenocarcinoma 7 | 2,713
dermatomyositis 6 | 933
interstitial cystitis 6 | 2,299
lung carcinoma 6 | 2,844
Alzheimer's disease 5 | 644
Duchenne muscular dystrophy 5 | 602
Neurodegenerative disease 5 | 383
Schizophrenia 5 | 501
diabetes mellitus 5 | 1,663
juvenile dermatomyositis 5 | 1,189
pituitary cancer 5 | 1,972
posterior fossa group B ependymoma 5 | 1,530
primary pancreatic ductal adenocarcinoma 5 | 1,271
tuberculosis 5 | 1,557
Cerebrovascular disease 4 | 231
Kidney disease 4 | 396
Multiple Sclerosis 4 | 498
Toxic encephalopathy 4 | 131
active Crohn's disease 4 | 918
breast carcinoma 4 | 1,614
cutaneous lupus erythematosus 4 | 1,056
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
nasopharyngeal carcinoma 4 | 1,056
pancreatic carcinoma 4 | 567
posterior fossa group A ependymoma 4 | 1,511
progressive supranuclear palsy 4 | 674
sonic hedgehog group medulloblastoma 4 | 1,482
Animal Mammary Neoplasms 3 | 136
Carcinoma 3 | 2,147
Crohn's disease 3 | 304
IGA Glomerulonephritis 3 | 454
Mammary Neoplasms, Experimental 3 | 150
Metachromatic leukodystrophy 3 | 13
Myocardial Infarction 3 | 126
Neuropathy 3 | 210
Parkinson's disease 3 | 364
acute myeloid leukemia 3 | 780
adrenocortical carcinoma 3 | 1,427
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic rhinosinusitis 3 | 512
ductal carcinoma in situ 3 | 1,745
hepatocellular carcinoma 3 | 532
hereditary spastic paraplegia 3 | 313
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
malignant mesothelioma 3 | 3,162
medulloblastoma 3 | 1,524
non-small cell lung cancer 3 | 2,798
Amyotrophic Lateral Sclerosis 2 | 431
Becker muscular dystrophy 2 | 187
Colonic Neoplasms 2 | 126
Degenerative polyarthritis 2 | 93
Dementia 2 | 129
Endometriosis 2 | 535
Eye disease 2 | 55
Heart disease 2 | 279
Hypertension 2 | 287
Liver carcinoma 2 | 217
Paraplegia 2 | 71
Polycystic Ovary Syndrome 2 | 332
Stomach Neoplasms 2 | 282
Vascular disease 2 | 281
cystic fibrosis 2 | 1,665
glioblastoma multiforme 2 | 347
mucosa-associated lymphoid tissue lymphoma 2 | 480
spina bifida 2 | 1,064
tuberculosis and treatment for 3 months 2 | 327
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 43 | 17,995
Cardiovascular System 43 | 17,958
Digestive Tract 43 | 18,473
Endocrine System 43 | 18,512
Female tissues 43 | 18,647
Male tissues 43 | 17,969
Nervous System 43 | 18,561
Skin and soft tissues 43 | 18,115
Urinary Tract 43 | 18,444
Liver and Pancreas 42 | 18,136
Respiratory system 42 | 17,484

Target Family

Non-IDG 24 | 11,971
Enzyme 14 | 4,146
Kinase 2 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

GO Process

substantia nigra development 43 | 43
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 148 ZNF148 Tbio Transcription Factor -1.71996 60.7 178
Myelin basic protein MBP Tbio Non-IDG -3.69577 5257.0 715
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.65303 525.6 142
ATP synthase F(0) complex subunit B1, mitochondrial ATP5F1 Tbio Enzyme -0.80065 5.85 92
Glutamate dehydrogenase 1, mitochondrial GLUD1 Tbio Enzyme -2.36170 245.3 134
Coiled-coil domain-containing protein 14 CCDC14 Tbio Non-IDG 0.39 0.36 23
78 kDa glucose-regulated protein HSPA5 Tchem Non-IDG -3.28487 2003.3 918
L-lactate dehydrogenase A chain LDHA Tchem Enzyme -2.99664 983.0 487
Transforming protein RhoA RHOA Tbio Enzyme -3.48838 3096.5 467
Myelin proteolipid protein PLP1 Tbio Non-IDG -3.13598 1391.2 152