Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

decreased body weight 1 | 161
decreased lean body mass 1 | 135
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 4 | 11,493
Branchiootorenal syndrome 2 | 8
Breast cancer 2 | 3,578
Cleft Palate 2 | 271
Cognitive delay 2 | 608
Dull intelligence 2 | 645
Global developmental delay 2 | 608
Highly variable severity 2 | 157
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Narrow nose 2 | 20
Poor school performance 2 | 645
Short stature 2 | 531
Variable expressivity 2 | 157
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
spina bifida 2 | 1,074
6 metacarpals 1 | 2
Abnormal dermatoglyphic pattern 1 | 24
Abnormality of the antihelix 1 | 10
Abnormality of the clavicle 1 | 14
Abnormally small eyeball on both sides 1 | 5
Ameloblastoma 1 | 24
Basal cell carcinoma of skin 1 | 2
Bilateral nanophthalmos 1 | 5
Branchioma 1 | 3
Branchiooculofacial syndrome 1 | 13
Branchiootic syndrome 1 | 12
Bulbous internal auditory canal 1 | 5
Choanal Atresia 1 | 42
Cleft uvula 1 | 27
Cochlear malformation 1 | 5
Coloboma 1 | 51
Coloboma, Ocular, Autosomal Dominant 1 | 6
Congenital Abnormalities 1 | 11
Congenital Abnormality 1 | 11
Congenital anomaly of nose 1 | 4
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Deep overbite 1 | 4
Euthyroid Goiter 1 | 3
Facial Dysmorphism with Multiple Malformations 1 | 2
Familial schizencephaly 1 | 4
Fara Chlupackova syndrome 1 | 2
Fetal Alcohol Spectrum Disorders 1 | 13
Fetal alcohol syndrome 1 | 22
Hand polydactyly 1 | 11
Hearing Loss, Mixed Conductive-Sensorineural 1 | 12
Hemiparesis 1 | 34
Holoprosencephaly 3 1 | 7
Hypoplastic cochlea 1 | 6
Hypoplastic tibiae-postaxial polydactyly syndrome 1 | 2
Incomplete partition of the cochlea type II 1 | 3
Lacrimal Duct Obstruction 1 | 16
Malformation of the nose 1 | 4
Malformed ossicles 1 | 3
Maxillary torus 1 | 2
Microphthalmia, Isolated, with Coloboma 1 1 | 8
Microphthalmia, bilateral 1 | 5
Middle ear malformations 1 | 5
Mild Mental Retardation 1 | 70
Mondini malformation 1 | 3
Narrowing of ear canal 1 | 13
Nose deformity 1 | 4
Otofaciocervical syndrome 1 | 2
Overbite 1 | 4
POLYDACTYLY, PREAXIAL II (disorder) 1 | 2
Parkinson Disease, Secondary 1 | 9
Pinched bridge of nose 1 | 14
Pinched nasal bridge 1 | 14
Polydactyly, Preaxial 2 1 | 2
Porencephaly 1 | 20
Posterior lingual occlusion of mandibular teeth 1 | 4
Preauricular skin tag 1 | 19
Prominent midpalatal ridge (torus palatinus) 1 | 2
Renal hypoplasia/aplasia 1 | 7
Renal steatosis 1 | 4
Respiratory Distress Syndrome, Adult 1 | 40
SOLITARY MEDIAN MAXILLARY CENTRAL INCISOR 1 | 5
SPINOCEREBELLAR ATAXIA 18 1 | 1
Scapular weakness 1 | 23
Schizencephaly 1 | 4
Secondary Parkinson Disease 1 | 10
Short bowel syndrome 1 | 16
Skin tag on the posterior cheek 1 | 19
Smith-Lemli-Opitz syndrome 1 | 9
Stenosis of external auditory canal 1 | 13
Syndactyly, Type IV 1 | 2
Thin face 1 | 54
Tibia, Hypoplasia of, with Polydactyly 1 | 2
Torus palatinus 1 | 2
Townes-Brocks syndrome 1 | 15
Vesicoureteral reflux 1 | 32
Winged scapula 1 | 23
spinocerebellar ataxia type 18 1 | 2

Tissue

Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678
Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192

Target Family

Non-IDG 4 | 12,091

GO Process

striated muscle tissue develop... 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interferon-related developmental regulator 1 IFRD1 Tbio Non-IDG -1.44715 36.1 100
Eyes absent homolog 1 EYA1 Tbio Non-IDG -2.06445 117.8 121
Eyes absent homolog 2 EYA2 Tbio Non-IDG -1.52868 34.3 208
Sonic hedgehog protein SHH Tchem Non-IDG -3.44287 2879.1 383