Development Level

Tchem 3 | 1,890
Tbio 1 | 10,625

IMPC Term

abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
decreased circulating insulin ... 1 | 75
decreased rib number 1 | 59
enlarged epididymis 1 | 27
enlarged heart 1 | 111
enlarged spleen 1 | 26
increased or absent threshold ... 1 | 128
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
preweaning lethality, incomple... 1 | 260
small testis 1 | 37

Disease

Cancer 3 | 2,346
lung cancer 3 | 4,466
ovarian cancer 3 | 8,484
Alzheimer's disease 2 | 644
Arthritis 2 | 248
HIV Infections 2 | 100
Lung Neoplasms 2 | 171
Prostatic Neoplasms 2 | 471
Vascular disease 2 | 281
glioblastoma 2 | 5,572
medulloblastoma, large-cell 2 | 6,234
osteosarcoma 2 | 7,933
psoriasis 2 | 6,685
subependymal giant cell astrocytoma 2 | 2,287
Acute kidney injury 1 | 65
Adenoma 1 | 165
Ataxia telangiectasia 1 | 31
Atherosclerosis 1 | 275
Autoimmune Diseases 1 | 33
Bladder Neoplasm 1 | 109
Blastic phase chronic myeloid leukemia 1 | 58
Brain Neoplasms 1 | 23
Brain disease 1 | 83
Brain infarction 1 | 17
Carcinoma, Transitional Cell 1 | 31
Cardiomyopathies 1 | 90
Ceroid lipofuscinosis, neuronal 1, infantile 1 | 10
Cholestasis 1 | 93
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic obstructive pulmonary disease 1 | 146
Chronic phase chronic myeloid leukemia 1 | 45
Colitis 1 | 46
Colonic Neoplasms 1 | 126
Demyelinating Diseases 1 | 7
Diabetes Mellitus, Experimental 1 | 106
Diabetes Mellitus, Non-Insulin-Dependent 1 | 157
Diabetic Retinopathy 1 | 53
Duchenne muscular dystrophy 1 | 602
Experimental Autoimmune Encephalomyelitis 1 | 7
Fatty Liver 1 | 48
Fatty liver disease 1 | 84
Fibrosis 1 | 40
Gaucher disease type 1 1 | 171
Heart Diseases 1 | 42
Heart conduction disease 1 | 65
Heart disease 1 | 279
Huntington's disease 1 | 72
Hyperglycemia 1 | 120
Impaired glucose tolerance 1 | 12
Insulin Resistance 1 | 48
Intestinal Neoplasms 1 | 11
Kidney Diseases 1 | 86
Kidney disease 1 | 396
Liver neoplasms 1 | 109
Lumbosacral lipoma 1 | 3
Lung Injury 1 | 20
Lung disease 1 | 132
Mammary Neoplasms 1 | 410
Metabolic syndrome X 1 | 155
Multiple Endocrine Neoplasia Type 1 1 | 30
Multiple Sclerosis 1 | 498
Muscular Dystrophy, Facioscapulohumeral 1 | 12
Myeloid Leukemia, Chronic 1 | 22
Myocardial Ischemia 1 | 169
Myocardial Reperfusion Injury 1 | 34
Neurodegenerative Disorders 1 | 37
Non-alcoholic Fatty Liver Disease 1 | 40
Papilloma 1 | 27
Paralysed 1 | 9
Parkinson's disease 1 | 364
Patellar tendinitis 1 | 2
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Pneumonia 1 | 133
Reperfusion Injury 1 | 84
Retinal Diseases 1 | 21
Squamous cell carcinoma of esophagus 1 | 82
Stomach Neoplasms 1 | 282
Streptococcal pneumonia 1 | 6
Vitamin K deficiency hemorrhagic disease 1 | 11
Waldenstrons macroglobulinemia 1 | 765
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
astrocytoma 1 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
axial spondyloarthropathy 1 | 28
diabetes mellitus 1 | 1,663
ductal carcinoma in situ 1 | 1,745
juvenile dermatomyositis 1 | 1,189
limb girdle muscular dystrophy 2A 1 | 156
non diabetic and post-ischemic heart failure 1 | 200
oligodendroglioma 1 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
pediatric high grade glioma 1 | 2,712
pilocytic astrocytoma 1 | 3,086
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,271
progressive supranuclear palsy 1 | 674
tuberculosis 1 | 1,557
type II diabetes mellitus and post-ischemic heart failure 1 | 89

Tissue

Blood and immune system 4 | 17,995
Cardiovascular System 4 | 17,958
Digestive Tract 4 | 18,473
Endocrine System 4 | 18,512
Female tissues 4 | 18,647
Liver and Pancreas 4 | 18,136
Male tissues 4 | 17,969
Nervous System 4 | 18,561
Respiratory system 4 | 17,484
Skin and soft tissues 4 | 18,115
Urinary Tract 4 | 18,444

Target Family

Kinase 2 | 634
Enzyme 1 | 4,146
Epigenetic 1 | 242

GO Process

stress-induced premature senes... 4 | 4
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43357 2997.4 1177
MAP kinase-activated protein kinase 5 MAPKAPK5 Tchem Kinase -1.83621 77.3 377
NAD-dependent protein deacetylase sirtuin-1 SIRT1 Tchem Epigenetic -3.40155 2958.6 656
Mitogen-activated protein kinase 14 MAPK14 Tchem Kinase -3.31846 2109.9 1387