Development Level

Tbio 13 | 11,445
Tchem 11 | 1,598

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal skin condition 1 | 6
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating sodium l... 1 | 22
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 16 | 11,493
ovarian cancer 16 | 8,520
Cancer 14 | 2,499
glioblastoma 12 | 5,792
atypical teratoid / rhabdoid tumor 11 | 5,112
medulloblastoma, large-cell 10 | 6,241
psoriasis 10 | 6,694
lung cancer 9 | 4,740
osteosarcoma 8 | 7,950
Astrocytoma, Pilocytic 6 | 3,081
Breast cancer 6 | 3,578
Kidney cancer 6 | 2,613
diabetes mellitus 6 | 1,728
Autosomal recessive predisposition 5 | 1,442
Lung Neoplasms 5 | 232
Schizophrenia 5 | 1,160
Vascular disease 5 | 319
adult high grade glioma 5 | 3,801
astrocytoma 5 | 1,146
ependymoma 5 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
primary pancreatic ductal adenocarcinoma 5 | 1,109
Arthritis 4 | 290
Cardiomyopathies 4 | 110
Cholestasis, Extrahepatic 4 | 25
Hyperalgesia 4 | 83
Obesity 4 | 678
Small head 4 | 374
acute myeloid leukemia 4 | 783
esophageal adenocarcinoma 4 | 737
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung carcinoma 4 | 2,843
Alzheimer's disease 3 | 658
Anemia 3 | 365
Brain Ischemia 3 | 110
Carcinoma, Squamous Cell 3 | 110
Depressive disorder 3 | 409
Disease Models, Animal 3 | 155
Heart disease 3 | 306
Hyperglycemia 3 | 137
Hypertrophy 3 | 17
Immunologic Deficiency Syndromes 3 | 113
Kidney disease 3 | 430
Liver Cirrhosis, Experimental 3 | 769
Mental Depression 3 | 333
Multiple myeloma 3 | 1,332
Neurodegenerative disease 3 | 414
Parkinson's disease 3 | 392
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Seizures 3 | 596
Short stature 3 | 531
Squamous cell carcinoma 3 | 129
Stomach Neoplasms 3 | 300
Toxic encephalopathy 3 | 141
Trigeminal Neuralgia 3 | 24
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Acquired scoliosis 2 | 281
Atopic dermatitis 2 | 952
Attention deficit hyperactivity disorder 2 | 278
Bipolar Disorder 2 | 666
Cerebrovascular disease 2 | 238
Cocaine-Related Disorders 2 | 92
Colonic Neoplasms 2 | 142
Curvature of spine 2 | 282
Down syndrome 2 | 499
Epilepsy 2 | 792
Eye disease 2 | 62
Female infertility 2 | 30
Flexion contracture of proximal interphalangeal joint 2 | 75
Gliosis 2 | 56
Heart failure 2 | 162
Hypertension 2 | 396
Inflammatory bowel disease 2 | 151
Lung disease 2 | 142
Multiple Sclerosis 2 | 540
Myocardial Ischemia 2 | 169
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Pneumonia 2 | 174
Reperfusion Injury 2 | 86
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074

Tissue

Blood and immune system 24 | 16,909
Cardiovascular System 24 | 15,192
Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Nervous System 24 | 16,725
Respiratory system 24 | 16,393
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678

Target Family

Kinase 11 | 634
Non-IDG 11 | 12,091
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

GO Process

stress-activated MAPK cascade 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase TAO2 TAOK2 Tchem Kinase -1.52454 36.1 154
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Dual specificity mitogen-activated protein kinase kinase 7 MAP2K7 Tchem Kinase -3.66356 3766.3 513
Angiotensinogen AGT Tbio Non-IDG -3.24591 1711.3 695
Mitogen-activated protein kinase kinase kinase 5 MAP3K5 Tchem Kinase -2.66223 525.4 1185
Cerebral cavernous malformations 2 protein CCM2 Tbio Non-IDG -1.88409 76.1 190
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248