Development Level

Tbio 84 | 11,445
Tchem 24 | 1,598
Tclin 10 | 613
Tdark 5 | 6,588

Collection

Kinase: IDG Consortium (Target... 3 | 125

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal bone structure 3 | 187
preweaning lethality, incomple... 3 | 499
abnormal lens morphology 2 | 81
decreased circulating choleste... 2 | 93
decreased hemoglobin content 2 | 68
increased blood urea nitrogen ... 2 | 48
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal cornea morphology 1 | 31
abnormal digit morphology 1 | 10
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal skin condition 1 | 6
cataract 1 | 92
decreased IgG3 level 1 | 1
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating free fat... 1 | 31
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased thermal nociceptive ... 1 | 9
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

ovarian cancer 79 | 8,520
Carcinoma 72 | 11,493
lung cancer 55 | 4,740
psoriasis 53 | 6,694
osteosarcoma 52 | 7,950
glioblastoma 43 | 5,792
Cancer 42 | 2,499
Multiple myeloma 37 | 1,332
medulloblastoma, large-cell 29 | 6,241
Breast cancer 28 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
atypical teratoid / rhabdoid tumor 24 | 5,112
ependymoma 24 | 4,679
adult high grade glioma 23 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
malignant mesothelioma 23 | 3,232
Kidney cancer 22 | 2,613
dermatomyositis 22 | 966
lung carcinoma 21 | 2,843
pancreatic cancer 21 | 2,398
non-small cell lung cancer 20 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
oligodendroglioma 19 | 2,850
subependymal giant cell astrocytoma 19 | 2,287
lung adenocarcinoma 18 | 2,716
HIV Infections 17 | 102
Waldenstrons macroglobulinemia 17 | 765
tuberculosis 17 | 2,010
group 3 medulloblastoma 16 | 4,104
interstitial cystitis 16 | 2,312
invasive ductal carcinoma 16 | 2,951
ulcerative colitis 16 | 1,819
Astrocytoma, Pilocytic 15 | 3,081
astrocytic glioma 15 | 2,597
astrocytoma 15 | 1,146
diabetes mellitus 15 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Pick disease 12 | 1,894
cystic fibrosis 12 | 1,696
group 4 medulloblastoma 12 | 1,855
Liver Cirrhosis, Experimental 11 | 769
juvenile dermatomyositis 11 | 1,187
Renal Cell Carcinoma 10 | 214
Seizures 10 | 596
esophageal adenocarcinoma 10 | 737
non primary Sjogren syndrome sicca 10 | 891
primary Sjogren syndrome 10 | 735
primary pancreatic ductal adenocarcinoma 10 | 1,109
Anemia 9 | 365
Breast Neoplasms 9 | 445
Epilepsy 9 | 792
Liver cancer 9 | 604
Mammary Neoplasms 9 | 425
Melanoma 9 | 711
Short stature 9 | 531
Stomach Neoplasms 9 | 300
colon cancer 9 | 1,478
Autosomal recessive predisposition 8 | 1,442
Byzanthine arch palate 8 | 194
Endometrial cancer 8 | 311
Hypoplastic mandible condyle 8 | 275
Immune system cancer 8 | 140
Intellectual disability 8 | 1,016
Lymphoid leukemia 8 | 160
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
acute myeloid leukemia 8 | 783
breast carcinoma 8 | 1,638
cutaneous lupus erythematosus 8 | 1,057
nasopharyngeal carcinoma 8 | 1,058
primitive neuroectodermal tumor 8 | 3,035
Acquired scoliosis 7 | 281
Crohn's disease 7 | 321
Curvature of spine 7 | 282
Downward slant of palpebral fissure 7 | 158
Dull intelligence 7 | 645
Frontal bossing 7 | 157
Large intestine cancer 7 | 126
Low intelligence 7 | 645
Mantle cell lymphoma 7 | 23
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Osteoporosis 7 | 363
Poor school performance 7 | 645
Rheumatoid arthritis 7 | 1,191
Schizophrenia 7 | 1,160
Strabismus 7 | 270
active Crohn's disease 7 | 922
active ulcerative colitis 7 | 764
acute quadriplegic myopathy 7 | 1,158
mucosa-associated lymphoid tissue lymphoma 7 | 484
Adenoma 6 | 167
Bladder Neoplasm 6 | 112
Blepharoptosis 6 | 231
Cardiac Arrhythmia 6 | 103
Delayed bone age 6 | 136
Exophthalmos 6 | 112
Low set ears 6 | 181
Muscle hypotonia 6 | 571
Urinary Bladder Neoplasms 6 | 114

Tissue

Digestive Tract 118 | 17,369
Endocrine System 116 | 18,159
Female tissues 116 | 17,400
Skin and soft tissues 116 | 17,230
Blood and immune system 114 | 16,909
Respiratory system 114 | 16,393
Urinary Tract 113 | 16,678
Liver and Pancreas 112 | 16,750
Male tissues 112 | 17,142
Nervous System 108 | 16,725
Cardiovascular System 105 | 15,192

Target Family

Non-IDG 51 | 12,091
Enzyme 48 | 4,145
Kinase 19 | 634
Transcription Factor 3 | 1,400
Epigenetic 2 | 242

GO Process

stimulatory C-type lectin rece... 123 | 123
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mucin-12 MUC12 Tbio Non-IDG -1.01744 9.74 60
Mucin-16 MUC16 Tbio Non-IDG -2.09951 138.4 0
C-type lectin domain family 4 member D CLEC4D Tbio Non-IDG -1.43609 25.1 193
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
Mucin-2 MUC2 Tbio Non-IDG -2.89417 752.2 0
Ubiquitin-conjugating enzyme E2 variant 1 UBE2V1 Tbio Non-IDG -1.33153 18.0 188
Mucin-5B MUC5B Tbio Non-IDG -3.20322 1552.2 177
NKG2-D type II integral membrane protein KLRK1 Tbio Non-IDG -1.53824 32.8 425
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574