Development Level

Tbio 10 | 11,445
Tchem 7 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

cataract 2 | 92
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal male genitalia morpho... 1 | 3
abnormal retina morphology 1 | 71
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating amylase ... 1 | 25
increased circulating creatini... 1 | 38
increased circulating unsatura... 1 | 1
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
oligodactyly 1 | 1
polydactyly 1 | 7
preweaning lethality, complete... 1 | 979
small kidney 1 | 16

Disease

Carcinoma 17 | 11,493
Autosomal recessive predisposition 8 | 1,442
Congenital adrenal hyperplasia 8 | 73
ovarian cancer 8 | 8,520
Breast cancer 6 | 3,578
adrenocortical carcinoma 6 | 1,428
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
Adenoma 5 | 167
Cancer 5 | 2,499
Osteoporosis 5 | 363
Prostatic Neoplasms 5 | 495
lung cancer 5 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Adrenal cortical adenoma 4 | 19
Adrenal hyperplasia 4 | 13
Antley-Bixler syndrome 4 | 16
Candidiasis of mouth 4 | 5
Candidiasis of skin 4 | 6
Cerebrotendinous xanthomatosis 4 | 13
Cholestasis 4 | 155
Coccidioidomycosis 4 | 8
Cushing's syndrome 4 | 48
Delayed bone age 4 | 136
Gynecomastia 4 | 64
Hyperaldosteronism 4 | 35
Hyperandrogenism 4 | 34
Hypertensive disease 4 | 292
Increase in blood pressure 4 | 119
Obesity 4 | 678
Pityriasis versicolor 4 | 19
Polycystic ovary syndrome 4 | 360
Renal salt wasting 4 | 18
Tinea corporis 4 | 25
Tinea cruris 4 | 12
Tinea pedis 4 | 29
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
Adenocarcinoma 3 | 122
Adrenocorticotropic hormone excess 3 | 5
Adrenogenital Syndrome 3 | 6
Anovulation 3 | 21
Astrocytoma, Pilocytic 3 | 3,081
Blastomycosis 3 | 12
Breast Neoplasms 3 | 445
Chromoblastomycosis 3 | 10
Congenital adrenal insufficiency 3 | 7
Conn's syndrome 3 | 22
Cryptorchidism 3 | 296
Disseminated candidiasis 3 | 4
Enlarged polycystic ovaries 3 | 10
Failure to gain weight 3 | 365
Fatty Liver 3 | 70
Histoplasmosis 3 | 13
Hypercortisolism 3 | 8
Hyperkalemia 3 | 17
Hypertension 3 | 396
Hypoaldosteronism 3 | 12
Hypogonadism 3 | 173
Hypokalemia 3 | 52
Increased circulating ACTH level 3 | 8
Infertility 3 | 188
Low to undetectable plasma cortisol 3 | 12
Male infertility 3 | 206
Mammary Neoplasms 3 | 425
Mineralocorticoid insufficiency 3 | 12
Neonatal onset 3 | 21
Paracoccidioidomycosis 3 | 12
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Pityriasis simplex 3 | 6
Premature ovarian failure 3 | 65
Pseudohermaphroditism 3 | 16
Schizophrenia 3 | 1,160
Seborrheic dermatitis 3 | 31
Short stature 3 | 531
Small testicle 3 | 75
acute quadriplegic myopathy 3 | 1,158
adult high grade glioma 3 | 3,801
chronic rhinosinusitis 3 | 512
cystic fibrosis 3 | 1,696
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 1,819
Growth delay 2 | 114
Growth failure 2 | 114
Penile hypospadias 2 | 106
Poor growth 2 | 114
Very poor growth 2 | 114
head and neck cancer and chronic obstructive pulmonary disease 2 | 239

Tissue

Endocrine System 22 | 18,159
Digestive Tract 20 | 17,369
Male tissues 20 | 17,142
Blood and immune system 19 | 16,909
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Nervous System 18 | 16,725
Skin and soft tissues 18 | 17,230
Respiratory system 17 | 16,393
Urinary Tract 17 | 16,678
Cardiovascular System 14 | 15,192

Target Family

Enzyme 14 | 4,145
Non-IDG 8 | 12,091

GO Process

sterol metabolic process 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cholesterol 24-hydroxylase CYP46A1 Tbio Enzyme -1.84856 68.6 197
Cytochrome P450 26A1 CYP26A1 Tchem Enzyme -2.44772 290.1 197
Ferredoxin-2, mitochondrial FDX2 Tdark Non-IDG -0.85150 6.83 4
Cytochrome P450 11B1, mitochondrial CYP11B1 Tclin Enzyme -2.66308 432.9 136
Emopamil-binding protein-like EBPL Tchem Non-IDG -0.73848 4.89 57
Cytochrome P450 11B2, mitochondrial CYP11B2 Tchem Non-IDG -2.82678 695.9 162
Cholesterol 7-alpha-monooxygenase CYP7A1 Tbio Enzyme -2.70498 494.6 94
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.09734 1226.2 369
Adrenodoxin, mitochondrial FDX1 Tbio Non-IDG -2.81884 673.3 46
Cytochrome P450 26C1 CYP26C1 Tbio Non-IDG -1.00437 8.71 78