Development Level

Tbio 8 | 10,625
Tchem 1 | 1,890
Tdark 1 | 7,003

IMPC Term

preweaning lethality, complete... 1 | 633

Disease

malignant mesothelioma 6 | 3,163
medulloblastoma, large-cell 6 | 6,234
osteosarcoma 6 | 7,933
ovarian cancer 6 | 8,492
ductal carcinoma in situ 5 | 1,745
lung cancer 5 | 4,473
psoriasis 5 | 6,685
glioblastoma 4 | 5,572
non-small cell lung cancer 4 | 2,798
pancreatic cancer 4 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
Atopic dermatitis 3 | 944
active Crohn's disease 3 | 918
astrocytoma 3 | 1,493
group 3 medulloblastoma 3 | 2,254
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
invasive ductal carcinoma 3 | 2,950
oligodendroglioma 3 | 2,849
primitive neuroectodermal tumor 3 | 3,031
Breast cancer 2 | 3,099
Methemoglobinemia 2 | 17
Multiple myeloma 2 | 1,328
Pelger-Huet anomaly 2 | 8
Pick disease 2 | 1,893
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 477
adrenocortical carcinoma 2 | 1,427
adult high grade glioma 2 | 2,148
atypical teratoid / rhabdoid tumor 2 | 4,369
breast carcinoma 2 | 1,614
chronic lymphocytic leukemia 2 | 244
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,475
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 832
group 4 medulloblastoma 2 | 1,875
lung carcinoma 2 | 2,844
non-inflammatory breast cancer 2 | 208
pilocytic astrocytoma 2 | 3,086
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 1,511
primary Sjogren syndrome 2 | 789
primary pancreatic ductal adenocarcinoma 2 | 1,271
Acquired metabolic disease 1 | 267
Antley-Bixler syndrome 1 | 15
Bipolar Disorder 1 | 266
Cardiac arrest 1 | 26
Cardiomyopathies 1 | 90
Cardiomyopathy 1 | 110
Cataract 1 | 104
Chondrodysplasia punctata 1 | 41
Chronic Kidney Diseases 1 | 22
Danon disease 1 | 6
Emery-Dreifuss muscular dystrophy 1 | 24
Endometriosis 1 | 535
Glycogen storage disease 1 | 37
Gout 1 | 93
Greenberg dysplasia 1 | 1
HEM dysplasia 1 | 1
Heart disease 1 | 279
Hypertrophic Cardiomyopathy 1 | 56
Hypervitaminosis A 1 | 8
Juvenile arthritis 1 | 124
Kidney disease 1 | 397
Lassa fever 1 | 10
Liver Neoplasms, Experimental 1 | 48
Metabolic acidosis 1 | 49
Paranoid personality disorder 1 | 5
Peripheral vascular disease 1 | 90
Pityriasis versicolor 1 | 18
Reynold's syndrome 1 | 1
Reynolds syndrome 1 | 1
Schizotypal personality disorder 1 | 8
Tinea capitis 1 | 12
Tinea corporis 1 | 25
Tinea cruris 1 | 12
Tinea pedis 1 | 30
Wolff-Parkinson-White syndrome 1 | 11
Zellweger Syndrome 1 | 38
acute quadriplegic myopathy 1 | 1,157
aldosterone-producing adenoma 1 | 664
atypical teratoid/rhabdoid tumor 1 | 1,095
cystic fibrosis 1 | 1,670
dermatomyositis 1 | 967
juvenile dermatomyositis 1 | 1,189
lung adenocarcinoma 1 | 2,714
mucosa-associated lymphoid tissue lymphoma 1 | 480
nasopharyngeal carcinoma 1 | 1,056
non diabetic and post-ischemic heart failure 1 | 200
pancreatic carcinoma 1 | 567
pediatric high grade glioma 1 | 2,712
progressive supranuclear palsy 1 | 674
sonic hedgehog group medulloblastoma 1 | 1,482
spina bifida 1 | 1,064
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis and treatment for 3 months 1 | 327
type II diabetes mellitus and post-ischemic heart failure 1 | 89

Tissue

Blood and immune system 10 | 17,995
Cardiovascular System 10 | 17,958
Digestive Tract 10 | 18,473
Endocrine System 10 | 18,512
Female tissues 10 | 18,647
Liver and Pancreas 10 | 18,136
Male tissues 10 | 17,969
Nervous System 10 | 18,561
Respiratory system 10 | 17,484
Skin and soft tissues 10 | 18,115
Urinary Tract 10 | 18,444

Target Family

Enzyme 9 | 4,146
Epigenetic 1 | 242

GO Process

sterol biosynthetic process 10 | 10
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lamin-B receptor LBR Tbio Epigenetic -3.00772 1003.7 120
Cholesterol 25-hydroxylase CH25H Tbio Enzyme -1.46188 31.1 33
NADH-cytochrome b5 reductase 2 CYB5R2 Tbio Enzyme -0.91042 7.51 42
NADH-cytochrome b5 reductase 1 CYB5R1 Tbio Enzyme -0.94354 7.13 99
Delta(14)-sterol reductase TM7SF2 Tbio Enzyme -1.09712 12.4 80
Phosphomevalonate kinase PMVK Tbio Enzyme -1.95241 91.0 130
Fatty acid hydroxylase domain-containing protein 2 FAXDC2 Tdark Enzyme 0.06 1.27 48
Squalene monooxygenase SQLE Tchem Enzyme -1.86405 67.2 89
5'-AMP-activated protein kinase subunit gamma-2 PRKAG2 Tbio Enzyme -1.93364 85.5 99
Methylsterol monooxygenase 1 MSMO1 Tbio Enzyme -1.61355 40.7 92