Development Level

Tbio 16 | 11,445
Tchem 16 | 1,598
Tclin 5 | 613

IMPC Phenotype

increased circulating creatini... 2 | 38
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal male genitalia morpho... 1 | 3
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
oligodactyly 1 | 1
polydactyly 1 | 7
small kidney 1 | 16

Disease

Carcinoma 24 | 11,493
Cancer 21 | 2,499
Prostatic Neoplasms 15 | 495
psoriasis 14 | 6,694
medulloblastoma, large-cell 12 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Chemical and Drug Induced Liver Injury 9 | 195
Liver disease 9 | 237
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
lung cancer 9 | 4,740
lung carcinoma 9 | 2,843
osteosarcoma 9 | 7,950
Autosomal recessive predisposition 8 | 1,442
diabetes mellitus 8 | 1,728
glioblastoma 8 | 5,792
ovarian cancer 8 | 8,520
tuberculosis 8 | 2,010
Obesity 7 | 678
adult high grade glioma 7 | 3,801
atypical teratoid / rhabdoid tumor 7 | 5,112
lung adenocarcinoma 7 | 2,716
pancreatic cancer 7 | 2,398
Breast Neoplasms 6 | 445
Liver carcinoma 6 | 240
Malaria 6 | 160
Mammary Neoplasms 6 | 425
Schizophrenia 6 | 1,160
interstitial cystitis 6 | 2,312
malignant mesothelioma 6 | 3,232
Carcinoma, Hepatocellular 5 | 228
Contact Dermatitis 5 | 81
Dermatitis, Contact 5 | 71
Drug-Related Side Effects and Adverse Reactions 5 | 62
Liver Cirrhosis, Experimental 5 | 769
Polycystic ovary syndrome 5 | 360
ependymoma 5 | 4,679
non-small cell lung cancer 5 | 2,890
Acute kidney injury 4 | 70
Adenocarcinoma 4 | 122
Adverse reaction to drug 4 | 61
Alcoholic Intoxication, Chronic 4 | 289
Cholestasis 4 | 155
Congenital adrenal hyperplasia 4 | 73
Endometriosis 4 | 540
Epilepsy 4 | 792
Hepatomegaly 4 | 285
Hypertension 4 | 396
Hypertensive disease 4 | 292
Lung Neoplasms 4 | 232
Melanoma 4 | 711
Neutropenia 4 | 72
Osteoporosis 4 | 363
esophageal adenocarcinoma 4 | 737
group 4 medulloblastoma 4 | 1,855
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
oligodendroglioma 4 | 2,850
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
ulcerative colitis 4 | 1,819
Adenoma 3 | 167
Ambiguous Genitalia 3 | 24
Astrocytoma, Pilocytic 3 | 3,081
Atopic dermatitis 3 | 952
Atrial Fibrillation 3 | 124
Barrett's esophagus 3 | 182
Breast cancer 3 | 3,578
Cardiomegaly 3 | 116
Colorectal Neoplasms 3 | 243
Coronary artery disease 3 | 268
Cushing's syndrome 3 | 48
Delayed Puberty 3 | 97
Endometrial Neoplasms 3 | 55
Fatty Liver 3 | 70
Gynecomastia 3 | 64
Hepatitis C 3 | 94
Hyperandrogenism 3 | 34
Increase in blood pressure 3 | 119
Major Depressive Disorder 3 | 301
Male infertility 3 | 206
Nicotine dependence 3 | 54
Pain 3 | 103
Penile hypospadias 3 | 106
Pick disease 3 | 1,894
Prostate cancer 3 | 175
Rheumatoid arthritis 3 | 1,191
Stomach Neoplasms 3 | 300
Unipolar Depression 3 | 250
Vascular disease 3 | 319
active ulcerative colitis 3 | 764
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
gastric carcinoma 3 | 807
group 3 medulloblastoma 3 | 4,104
nasopharyngeal carcinoma 3 | 1,058
nephrosclerosis 3 | 333
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Liver and Pancreas 36 | 16,750
Skin and soft tissues 36 | 17,230
Digestive Tract 35 | 17,369
Female tissues 34 | 17,400
Male tissues 34 | 17,142
Endocrine System 33 | 18,159
Urinary Tract 33 | 16,678
Blood and immune system 32 | 16,909
Respiratory system 29 | 16,393
Nervous System 25 | 16,725
Cardiovascular System 16 | 15,192

Target Family

Enzyme 26 | 4,145
Non-IDG 10 | 12,091
Nuclear Receptor 1 | 48

GO Process

steroid metabolic process 37 | 37
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dehydrogenase/reductase SDR family member 4 DHRS4 Tbio Enzyme -1.65486 46.6 122
Sulfotransferase 1A3 SULT1A3 Tbio Enzyme -2.23459 201.6 133
Sulfotransferase 1A4 SULT1A3 Tbio Enzyme -2.23459 201.6 40
UDP-glucuronosyltransferase 2B15 UGT2B15 Tbio Enzyme -1.79589 61.5 83
Estrogen sulfotransferase SULT1E1 Tchem Enzyme -2.97379 932.9 156
Sulfotransferase family cytosolic 1B member 1 SULT1B1 Tbio Enzyme -1.38121 24.5 160
Cytochrome P450 2D6 CYP2D6 Tclin Enzyme -3.53105 3484.9 433
Cytochrome P450 2C8 CYP2C8 Tchem Non-IDG -2.55207 348.9 159
Sulfotransferase family cytosolic 2B member 1 SULT2B1 Tbio Enzyme -2.31607 178.2 185
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.09734 1226.2 369