Development Level

Tbio 14 | 10,625
Tchem 9 | 1,890
Tclin 5 | 602
Tdark 3 | 7,003

IMPC Term

abnormal lens morphology 3 | 73
preweaning lethality, complete... 3 | 633
immune system phenotype 2 | 17
increased circulating alkaline... 2 | 119
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal motor coordination/ b... 1 | 4
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased exploration in new e... 1 | 9
decreased lean body mass 1 | 195
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged urinary bladder 1 | 4
hyperactivity 1 | 108
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased fasted circulating g... 1 | 68
increased rib number 1 | 41
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
small kidney 1 | 10

Disease

ovarian cancer 15 | 8,484
psoriasis 14 | 6,685
osteosarcoma 11 | 7,933
malignant mesothelioma 10 | 3,162
Breast cancer 9 | 3,094
Congenital adrenal hyperplasia 8 | 74
adrenocortical carcinoma 8 | 1,427
glioblastoma 8 | 5,572
lung cancer 8 | 4,466
ulcerative colitis 8 | 2,087
Polycystic Ovary Syndrome 7 | 332
Prostatic Neoplasms 7 | 471
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
pancreatic cancer 7 | 2,300
Cancer 6 | 2,346
Endometriosis 6 | 535
Infertility 6 | 163
cystic fibrosis 6 | 1,665
interstitial cystitis 6 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
Hyperandrogenism 5 | 32
Peripheral Neuropathy 5 | 303
atypical teratoid / rhabdoid tumor 5 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
lung adenocarcinoma 5 | 2,713
medulloblastoma, large-cell 5 | 6,234
pilocytic astrocytoma 5 | 3,086
pituitary cancer 5 | 1,972
Amenorrhea 4 | 60
Antley-Bixler syndrome 4 | 15
Hypogonadism 4 | 70
Hypospadias 4 | 65
Multiple myeloma 4 | 1,327
Pseudohermaphroditism 4 | 16
Waldenstrons macroglobulinemia 4 | 765
breast carcinoma 4 | 1,614
colon cancer 4 | 1,475
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
lung carcinoma 4 | 2,844
non-small cell lung cancer 4 | 2,798
oligodendroglioma 4 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pediatric high grade glioma 4 | 2,712
posterior fossa group B ependymoma 4 | 1,530
primary pancreatic ductal adenocarcinoma 4 | 1,271
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 1,557
Alzheimer's disease 3 | 644
Endometrial Neoplasms 3 | 50
Liver carcinoma 3 | 217
Mammary Neoplasms 3 | 410
Pick disease 3 | 1,893
Prostate cancer 3 | 172
active Crohn's disease 3 | 918
acute myeloid leukemia 3 | 780
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
astrocytoma 3 | 1,493
dermatomyositis 3 | 933
ependymoma 3 | 2,514
fibroadenoma 3 | 557
primary Sjogren syndrome 3 | 789
sonic hedgehog group medulloblastoma 3 | 1,482
Addison's disease 2 | 29
Adenoma 2 | 165
Anovulation 2 | 20
Anxiety disorder 2 | 22
Autistic Disorder 2 | 320
Benign prostatic hyperplasia 2 | 7
Cerebrovascular disease 2 | 231
Chagas disease 2 | 34
Cushing's syndrome 2 | 47
Duchenne muscular dystrophy 2 | 602
Female infertility 2 | 28
Hepatic encephalopathy 2 | 25
Hypercortisolism 2 | 8
Hypopituitarism 2 | 36
Klinefelter's syndrome 2 | 59
Liver Cirrhosis, Experimental 2 | 108
Male infertility 2 | 170
Multiple Sclerosis 2 | 498
Parkinson's disease 2 | 364
Pityriasis versicolor 2 | 18
Pontocerebellar hypoplasia 2 | 29
Premature ovarian failure 2 | 64
Primary pigmented nodular adrenocortical disease 2 | 12
Spontaneous abortion 2 | 108
Testicular Leydig cell tumor 2 | 2
Tinea corporis 2 | 25
Tinea cruris 2 | 12
Tinea pedis 2 | 30
Toxic encephalopathy 2 | 131
atypical teratoid/rhabdoid tumor 2 | 1,095
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,056
invasive ductal carcinoma 2 | 2,950
medulloblastoma 2 | 1,524
nasopharyngeal carcinoma 2 | 1,056
progressive supranuclear palsy 2 | 674

Tissue

Liver and Pancreas 31 | 18,136
Male tissues 31 | 17,969
Cardiovascular System 30 | 17,958
Digestive Tract 30 | 18,473
Endocrine System 30 | 18,512
Female tissues 30 | 18,647
Nervous System 30 | 18,561
Urinary Tract 30 | 18,444
Blood and immune system 29 | 17,995
Respiratory system 29 | 17,484
Skin and soft tissues 29 | 18,115

Target Family

Enzyme 19 | 4,146
Non-IDG 8 | 11,971
Transcription Factor 3 | 1,400
Nuclear Receptor 1 | 48

GO Process

steroid biosynthetic process 31 | 31
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.80784 708.8 168
Nuclear receptor subfamily 0 group B member 1 NR0B1 Tchem Nuclear Receptor -2.70036 522.8 435
Very-long-chain 3-oxoacyl-CoA reductase HSD17B12 Tbio Enzyme -1.34964 31.9 103
Retinol dehydrogenase 8 RDH8 Tbio Enzyme -1.02631 12.5 0
Squalene synthase FDFT1 Tchem Enzyme -2.52429 343.3 251
Estradiol 17-beta-dehydrogenase 11 HSD17B11 Tbio Enzyme -0.96309 10.8 116
Transcriptional-regulating factor 1 TRERF1 Tbio Transcription Factor -0.58677 5.14 132
SCP2 sterol-binding domain-containing protein 1 SCP2D1 Tdark Non-IDG 0.09 0.28 35
Estradiol 17-beta-dehydrogenase 1 HSD17B1 Tchem Enzyme -2.31436 205.7 174
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 HSD3B1 Tchem Enzyme -2.57376 345.2 223