Development Level

Tbio 13 | 11,651
Tchem 6 | 1,388
Tclin 3 | 612
Tdark 3 | 6,593

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal lens morphology 2 | 81
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal male genitalia morpho... 1 | 3
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged urinary bladder 1 | 8
hypoactivity 1 | 132
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating potassiu... 1 | 29
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
oligodactyly 1 | 1
polydactyly 1 | 7
small kidney 1 | 16

Disease

Carcinoma 15 | 11,493
psoriasis 13 | 6,694
ovarian cancer 11 | 8,520
osteosarcoma 10 | 7,950
Breast cancer 8 | 3,578
Congenital adrenal hyperplasia 8 | 73
lung cancer 8 | 4,740
Polycystic ovary syndrome 7 | 360
interstitial cystitis 7 | 2,312
malignant mesothelioma 7 | 3,232
Autosomal recessive predisposition 6 | 1,442
Cancer 6 | 2,499
Hyperandrogenism 6 | 34
Infertility 6 | 188
adrenocortical carcinoma 6 | 1,428
glioblastoma 6 | 5,792
pituitary cancer 6 | 1,972
Gynecomastia 5 | 64
Penile hypospadias 5 | 106
Prostatic Neoplasms 5 | 495
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
ulcerative colitis 5 | 1,819
Adrenogenital Syndrome 4 | 6
Amenorrhea 4 | 58
Antley-Bixler syndrome 4 | 16
Astrocytoma, Pilocytic 4 | 3,081
Cryptorchidism 4 | 296
Hypogonadism 4 | 173
Hypospadias 4 | 53
Liver Cirrhosis, Experimental 4 | 769
Osteoporosis 4 | 363
Primary hypogonadism 4 | 37
Pseudohermaphroditism 4 | 16
Renal salt wasting 4 | 18
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic cancer 4 | 2,398
subependymal giant cell astrocytoma 4 | 2,287
Adenoma 3 | 167
Adrenal Hyperplasia, Congenital 3 | 9
Adrenal hyperplasia 3 | 13
Anovulation 3 | 21
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Decreased fertility in females 3 | 20
Delayed Puberty 3 | 97
Delayed bone age 3 | 136
Elevated follicle stimulating hormone 3 | 15
Elevated luteinizing hormone 3 | 14
Endometriosis 3 | 540
Enlarged polycystic ovaries 3 | 10
Liver carcinoma 3 | 240
Low to undetectable plasma cortisol 3 | 12
Male Pseudohermaphroditism 3 | 19
Male infertility 3 | 206
Mammary Neoplasms 3 | 425
Primary physiologic amenorrhea 3 | 55
Prostate cancer 3 | 175
Small testicle 3 | 75
Waldenstrons macroglobulinemia 3 | 765
active ulcerative colitis 3 | 764
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
Abortion, Spontaneous 2 | 109
Advanced bone age 2 | 35
Alzheimer's disease 2 | 658
Autistic Disorder 2 | 364
Azoospermia 2 | 110
Chagas disease 2 | 39
Cushing's syndrome 2 | 48
Female infertility 2 | 30
Hyperaldosteronism 2 | 35
Hypercortisolism 2 | 8
Hypertrophy of clitoris 2 | 40
Increased circulating ACTH level 2 | 8
Infertility, Female 2 | 28
Insulin Resistance 2 | 72
Pityriasis versicolor 2 | 19
Spontaneous abortion 2 | 113
Tinea corporis 2 | 25
Tinea pedis 2 | 29
active Crohn's disease 2 | 922
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
fibroadenoma 2 | 559
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010

Tissue

Endocrine System 25 | 18,159
Digestive Tract 23 | 17,369
Female tissues 23 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Skin and soft tissues 22 | 17,230
Blood and immune system 21 | 16,909
Nervous System 21 | 16,725
Urinary Tract 21 | 16,678
Respiratory system 20 | 16,393
Cardiovascular System 15 | 15,192

Target Family

Enzyme 14 | 4,145
Non-IDG 7 | 12,091
Transcription Factor 3 | 1,400
Nuclear Receptor 1 | 48

GO Process

steroid biosynthetic process 25 | 25
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 HSD3B2 Tclin Enzyme -2.06512 109.2 126
Pre-B-cell leukemia transcription factor 1 PBX1 Tbio Transcription Factor -2.30640 200.0 232
Histidine triad nucleotide-binding protein 2, mitochondrial HINT2 Tbio Non-IDG -1.39416 24.2 84
Estradiol 17-beta-dehydrogenase 1 HSD17B1 Tchem Enzyme -2.36315 220.8 198
Prolactin receptor PRLR Tbio Non-IDG -2.77379 616.6 494
Squalene synthase FDFT1 Tchem Enzyme -2.57966 374.3 291
Non-specific lipid-transfer protein SCP2 Tchem Non-IDG -2.66328 485.4 314
Aromatase CYP19A1 Tclin Enzyme -3.38322 2409.0 449
NADPH:adrenodoxin oxidoreductase, mitochondrial FDXR Tbio Enzyme -2.61525 376.3 201
Lanosterol 14-alpha demethylase CYP51A1 Tchem Enzyme -2.75707 588.4 158