Development Level

Tbio 42 | 11,445
Tchem 6 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to o... 4 | 239
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating choleste... 2 | 93
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
increased bone mineral density 2 | 72
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal urinary bladder morph... 1 | 11
aorta dilation 1 | 3
cataract 1 | 92
decreased B cell number 1 | 5
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
edema 1 | 59
embryonic growth retardation 1 | 106
female infertility 1 | 60
increased body length 1 | 32
increased startle reflex 1 | 112
mammalian phenotype 1 | 17
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
sclerocornea 1 | 2
small spleen 1 | 19
small testis 1 | 58
thin ventricular wall 1 | 24

Disease

Carcinoma 35 | 11,493
osteosarcoma 34 | 7,950
ovarian cancer 33 | 8,520
psoriasis 23 | 6,694
Cancer 21 | 2,499
lung cancer 19 | 4,740
atypical teratoid / rhabdoid tumor 18 | 5,112
medulloblastoma, large-cell 17 | 6,241
group 3 medulloblastoma 16 | 4,104
Kidney cancer 14 | 2,613
glioblastoma 14 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Breast cancer 11 | 3,578
ependymoma 11 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
malignant mesothelioma 11 | 3,232
primitive neuroectodermal tumor 11 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
astrocytic glioma 9 | 2,597
acute quadriplegic myopathy 8 | 1,158
adult high grade glioma 8 | 3,801
subependymal giant cell astrocytoma 8 | 2,287
tuberculosis 8 | 2,010
Astrocytoma, Pilocytic 7 | 3,081
Breast Neoplasms 7 | 445
Cryptorchidism 7 | 296
Mammary Neoplasms 7 | 425
Pick disease 7 | 1,894
Waldenstrons macroglobulinemia 7 | 765
pancreatic cancer 7 | 2,398
pituitary cancer 7 | 1,972
Dull intelligence 6 | 645
Immune system cancer 6 | 140
Intellectual disability 6 | 1,016
Long philtrum 6 | 137
Low intelligence 6 | 645
Lymphoid leukemia 6 | 160
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Schizophrenia 6 | 1,160
Short stature 6 | 531
adrenocortical carcinoma 6 | 1,428
cystic fibrosis 6 | 1,696
juvenile dermatomyositis 6 | 1,187
oligodendroglioma 6 | 2,850
Bushy eyebrows 5 | 49
Byzanthine arch palate 5 | 194
Cognitive delay 5 | 608
Concave bridge of nose 5 | 195
Depressed nasal bridge 5 | 195
Depressed nasal root/bridge 5 | 195
Failure to gain weight 5 | 365
Fetal Growth Retardation 5 | 189
Generalized hirsutism 5 | 36
Global developmental delay 5 | 608
Hypoplastic mandible condyle 5 | 275
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Long eyelashes 5 | 37
Mandibular hypoplasia 5 | 275
Mental and motor retardation 5 | 608
Micrognathism 5 | 275
Pediatric failure to thrive 5 | 365
Penile hypospadias 5 | 106
Rheumatoid arthritis 5 | 1,191
Sensorineural Hearing Loss (disorder) 5 | 284
Short neck 5 | 140
Small head 5 | 374
Speech Disorders 5 | 58
Thin lips 5 | 49
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
dermatomyositis 5 | 966
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
nasopharyngeal carcinoma 5 | 1,058
ulcerative colitis 5 | 1,819
Anteverted nostril 4 | 191
Attention deficit hyperactivity disorder 4 | 278
Blepharoptosis 4 | 231
Conductive hearing loss 4 | 123
Congenital hypoplasia of penis 4 | 176
Endometrial cancer 4 | 311
Feeding difficulties in infancy 4 | 175
Hernia, Inguinal 4 | 89
Liver cancer 4 | 604
Melanoma 4 | 711
Multiple myeloma 4 | 1,332
Skin cancer 4 | 469
Stomach Neoplasms 4 | 300
Strabismus 4 | 270
Ventricular Septal Defects 4 | 119
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
breast carcinoma 4 | 1,638
interstitial cystitis 4 | 2,312
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064

Tissue

Endocrine System 50 | 18,159
Blood and immune system 49 | 16,909
Digestive Tract 49 | 17,369
Female tissues 49 | 17,400
Urinary Tract 49 | 16,678
Male tissues 48 | 17,142
Nervous System 48 | 16,725
Respiratory system 48 | 16,393
Skin and soft tissues 48 | 17,230
Liver and Pancreas 47 | 16,750
Cardiovascular System 46 | 15,192

Target Family

Enzyme 20 | 4,145
Non-IDG 17 | 12,091
Transcription Factor 7 | 1,400
Epigenetic 3 | 242
Kinase 2 | 634
GPCR 1 | 408
Nuclear Receptor 1 | 48

GO Process

stem cell population maintenan... 51 | 51
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Eomesodermin homolog EOMES Tbio Transcription Factor -2.37902 230.4 333
Zinc finger protein 358 ZNF358 Tdark Transcription Factor 0.02 1.33 96
Steroid hormone receptor ERR2 ESRRB Tchem Nuclear Receptor -1.95523 86.9 173
N6-adenosine-methyltransferase catalytic subunit METTL3 Tbio Enzyme -1.76174 60.5 94
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
U6 snRNA-associated Sm-like protein LSm1 LSM1 Tbio Non-IDG -2.01162 106.0 191
T-box transcription factor TBX3 TBX3 Tbio Transcription Factor -2.42253 255.6 328
Histone-lysine N-methyltransferase SETD1A SETD1A Tbio Epigenetic -2.57679 365.2 125
Protein-arginine deiminase type-4 PADI4 Tchem Enzyme -2.48712 319.5 342
Terminal uridylyltransferase 4 ZCCHC11 Tbio Enzyme -1.18900 14.5 147