Development Level

Tbio 15 | 11,445
Tchem 5 | 1,598
Tclin 4 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal heart morphology 2 | 162
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal vertebrae morphology 1 | 18
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112
short tibia 1 | 97

Disease

Carcinoma 17 | 11,493
ovarian cancer 17 | 8,520
ependymoma 16 | 4,679
glioblastoma 16 | 5,792
lung cancer 15 | 4,740
Cancer 14 | 2,499
invasive ductal carcinoma 14 | 2,951
atypical teratoid / rhabdoid tumor 13 | 5,112
osteosarcoma 13 | 7,950
Breast cancer 12 | 3,578
medulloblastoma, large-cell 12 | 6,241
adult high grade glioma 11 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
malignant mesothelioma 11 | 3,232
non-small cell lung cancer 11 | 2,890
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
lung carcinoma 10 | 2,843
primitive neuroectodermal tumor 10 | 3,035
psoriasis 10 | 6,694
Astrocytoma, Pilocytic 9 | 3,081
astrocytic glioma 9 | 2,597
cystic fibrosis 9 | 1,696
interstitial cystitis 9 | 2,312
lung adenocarcinoma 9 | 2,716
oligodendroglioma 9 | 2,850
Kidney cancer 7 | 2,613
breast carcinoma 7 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
ulcerative colitis 7 | 1,819
adrenocortical carcinoma 6 | 1,428
colon cancer 6 | 1,478
ductal carcinoma in situ 6 | 1,745
pancreatic cancer 6 | 2,398
Atopic dermatitis 5 | 952
Breast Neoplasms 5 | 445
Pick disease 5 | 1,894
Skin cancer 5 | 469
Vascular disease 5 | 319
diabetes mellitus 5 | 1,728
gastric carcinoma 5 | 807
tuberculosis 5 | 2,010
Diabetic retinopathy 4 | 56
Endometriosis 4 | 540
Hypertension 4 | 396
Mammary Neoplasms 4 | 425
Melanoma 4 | 711
Polycystic ovary syndrome 4 | 360
pituitary cancer 4 | 1,972
Cerebrovascular disease 3 | 238
Intellectual disability 3 | 1,016
Liver cancer 3 | 604
Tetralogy of Fallot 3 | 63
cutaneous lupus erythematosus 3 | 1,057
fibroadenoma 3 | 559
group 4 medulloblastoma 3 | 1,855
hepatocellular carcinoma 3 | 547
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
substance-related disorder 3 | 162
urothelial carcinoma 3 | 318
Alcoholic Intoxication, Chronic 2 | 289
Atherosclerosis 2 | 291
Attention deficit hyperactivity disorder 2 | 278
Colonic Neoplasms 2 | 142
Coronary artery disease 2 | 268
Esophageal Squamous Cell Carcinoma 2 | 77
Glaucoma 2 | 239
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Kidney disease 2 | 430
Liver Cirrhosis 2 | 181
Lung Neoplasms 2 | 232
Lymphedema 2 | 42
Multiple myeloma 2 | 1,332
Neoplasm Invasiveness 2 | 161
Phenotypic variability 2 | 150
Placental abruption 2 | 18
Prostatic Neoplasms 2 | 495
Schizophrenia 2 | 1,160
Squamous cell carcinoma of esophagus 2 | 77
Strabismus 2 | 270
Substance-Related Disorders 2 | 115
Type 2 diabetes mellitus 2 | 272
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
cystic fibrosis and chronic rhinosinusitis 2 | 214
esophageal adenocarcinoma 2 | 737
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
non-small cell lung carcinoma 2 | 317
primary Sjogren syndrome 2 | 735
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Blood and immune system 24 | 16,909
Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Nervous System 24 | 16,725
Respiratory system 24 | 16,393
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 12 | 12,091
Enzyme 5 | 4,145
Kinase 3 | 634
Transcription Factor 3 | 1,400
GPCR 1 | 408

GO Process

sprouting angiogenesis 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adhesion G protein-coupled receptor A2 ADGRA2 Tbio GPCR -1.45203 30.0 211
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Vascular endothelial growth factor receptor 3 FLT4 Tclin Kinase -2.72966 518.8 744
Placenta growth factor PGF Tclin Non-IDG -3.52194 3429.0 630
E3 ubiquitin-protein ligase RNF213 RNF213 Tbio Enzyme -1.80934 56.8 144
Receptor activity-modifying protein 2 RAMP2 Tclin Non-IDG -1.88714 81.5 157
R-spondin-3 RSPO3 Tbio Non-IDG -1.33286 23.2 138
Angiopoietin-1 receptor TEK Tclin Kinase -3.00257 906.7 1009
Alpha-parvin PARVA Tbio Non-IDG -2.38332 236.6 0
Lysyl oxidase homolog 2 LOXL2 Tbio Enzyme -2.24186 173.0 274