Development Level

Tbio 12 | 11,445

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
impaired righting response 1 | 26
increased fasted circulating g... 1 | 76
increased total body fat amoun... 1 | 134

Disease

Carcinoma 10 | 11,493
ovarian cancer 9 | 8,520
osteosarcoma 7 | 7,950
group 3 medulloblastoma 6 | 4,104
Retinitis Pigmentosa 5 | 226
medulloblastoma, large-cell 5 | 6,241
oligodendroglioma 5 | 2,850
psoriasis 5 | 6,694
Abnormality of retinal pigmentation 4 | 111
Abnormality of the retinal vasculature 4 | 59
Anteverted nostril 4 | 191
Atypical scarring of skin 4 | 62
Blind Vision 4 | 111
Blindness, Legal 4 | 110
Broad flat nasal bridge 4 | 236
Cataract 4 | 297
Conductive hearing loss 4 | 123
Congenital anomaly of testis 4 | 52
Congenital hypoplasia of penis 4 | 176
Dull intelligence 4 | 645
Electroretinogram abnormal 4 | 95
Glaucoma 4 | 239
Hyperinsulinism 4 | 133
Hypogonadism 4 | 173
Intellectual disability 4 | 1,016
Keratoconus 4 | 113
Lens Opacities 4 | 231
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Nasal bridge wide 4 | 236
Night blindness, progressive 4 | 51
Nystagmus 4 | 317
Obesity 4 | 678
Ophthalmoplegia 4 | 106
Optic Atrophy 4 | 242
Photodysphoria 4 | 121
Photophobia 4 | 121
Poor school performance 4 | 645
Retinal pigment epithelial abnormality 4 | 111
Sensorineural Hearing Loss (disorder) 4 | 284
ependymoma 4 | 4,679
Difficulties with night vision 3 | 87
Night Blindness 3 | 101
astrocytoma 3 | 1,146
diabetes mellitus 3 | 1,728
malignant mesothelioma 3 | 3,232
Gaucher disease type 1 2 | 180
Keratosis 2 | 37
Kidney cancer 2 | 2,613
Multiple myeloma 2 | 1,332
acute myeloid leukemia 2 | 783
dermatomyositis 2 | 966
glioblastoma 2 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
Cancer 1 | 2,499
Crohn's disease 1 | 321
Disease Progression 1 | 136
Endometrial Neoplasms 1 | 55
Endometrial cancer 1 | 311
Enhanced S-cone syndrome 1 | 17
HIV Infections 1 | 102
Large intestine cancer 1 | 126
Low Vision 1 | 174
Muscular atrophy 1 | 71
Polycystic ovary syndrome 1 | 360
Retinal Degeneration 1 | 106
Retinal blind spot 1 | 11
Retinal depigmentation 1 | 12
Retinitis pigmentosa 11 1 | 59
Rheumatoid arthritis 1 | 1,191
Schizophrenia 1 | 1,160
Scotoma 1 | 22
Spinal muscular atrophy 1 | 34
Stomach Neoplasms 1 | 300
Visual Impairment 1 | 174
Visual field constriction 1 | 36
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
adult high grade glioma 1 | 3,801
aldosterone-producing adenoma 1 | 665
atypical teratoid/rhabdoid tumor 1 | 357
facioscapulohumeral dystrophy 1 | 288
gastric cancer 1 | 459
glioblastoma multiforme 1 | 142
hepatocellular carcinoma 1 | 547
juvenile dermatomyositis 1 | 1,187
nasopharyngeal carcinoma 1 | 1,058
ovarian neoplasm 1 | 99
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Non-IDG 10 | 12,091
Enzyme 2 | 4,145

GO Process

spliceosomal tri-snRNP complex... 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/arginine-rich splicing factor 12 SRSF12 Tbio Non-IDG -0.09691 1.17 22
Pre-mRNA-processing-splicing factor 8 PRPF8 Tbio Non-IDG -1.73166 55.2 78
Serine/arginine-rich splicing factor 10 SRSF10 Tbio Non-IDG -1.84057 68.1 194
Probable ATP-dependent RNA helicase DDX20 DDX20 Tbio Enzyme -1.58249 38.0 250
Protein AAR2 homolog AAR2 Tbio Non-IDG -1.08814 13.6 56
U4/U6 small nuclear ribonucleoprotein Prp31 PRPF31 Tbio Non-IDG -1.84397 72.4 216
U4/U6 small nuclear ribonucleoprotein Prp3 PRPF3 Tbio Non-IDG -1.73686 54.3 123
Pre-mRNA-processing factor 6 PRPF6 Tbio Non-IDG -1.39926 24.5 171
Pre-mRNA-processing factor 19 PRPF19 Tbio Non-IDG -1.71524 54.2 234
Squamous cell carcinoma antigen recognized by T-cells 3 SART3 Tbio Non-IDG -1.52384 38.1 175