Development Level

Tbio 15 | 11,445
Tchem 6 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal bone structure 1 | 187
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal vocalization 1 | 21
decreased circulating glucose ... 1 | 126
decreased fluid intake 1 | 3
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
increased body length 1 | 32
increased bone mineral content 1 | 108
increased urine microalbumin l... 1 | 2
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 17 | 11,493
osteosarcoma 13 | 7,950
ovarian cancer 13 | 8,520
psoriasis 12 | 6,694
group 3 medulloblastoma 11 | 4,104
atypical teratoid / rhabdoid tumor 9 | 5,112
glioblastoma 9 | 5,792
medulloblastoma, large-cell 9 | 6,241
lung cancer 7 | 4,740
Multiple myeloma 6 | 1,332
ependymoma 6 | 4,679
malignant mesothelioma 6 | 3,232
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Kidney cancer 4 | 2,613
Pick disease 4 | 1,894
acute myeloid leukemia 4 | 783
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
nasopharyngeal carcinoma 4 | 1,058
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
Joubert syndrome 3 | 66
Malignant tumor of ovary 3 | 25
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Acute lymphoid leukemia 2 | 25
Anaplastic large T-cell systemic malignant lymphoma 2 | 10
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Burkitt's lymphoma 2 | 15
Carcinoma of breast 2 | 11
Carcinoma of female breast 2 | 20
Diffuse non-Hodgkin's lymphoma, large cell 2 | 12
Endometriosis 2 | 540
Follicular non-Hodgkin's lymphoma 2 | 17
Gestational trophoblastic neoplasia 2 | 14
HER2-positive carcinoma of breast 2 | 21
Hodgkin's disease 2 | 18
Hypertensive disorder 2 | 56
Intellectual disability 2 | 1,016
Kaposi's sarcoma 2 | 22
Langerhans cell histiocytosis, disseminated 2 | 10
Liposarcoma 2 | 20
Malignant tumor of head and/or neck 2 | 15
Malignant tumor of prostate 2 | 26
Malignant tumor of stomach 2 | 12
Malignant tumor of testis 2 | 11
Metastatic Breast Carcinoma 2 | 21
Metastatic Prostate Carcinoma 2 | 18
Microcephaly 2 | 166
Mycosis fungoides 2 | 29
Nephroblastoma 2 | 51
Neuroblastoma 2 | 80
Non-Hodgkin's lymphoma 2 | 22
Ocular hypertension 2 | 42
Open-angle glaucoma 2 | 27
Peripheral T-cell lymphoma 2 | 25
Primary cutaneous T-cell lymphoma 2 | 29
Retinitis Pigmentosa 2 | 226
Rhabdomyosarcoma 2 | 39
Schizophrenia 2 | 1,160
Secondary malignant neoplasm of pancreas 2 | 10
Waldenstrons macroglobulinemia 2 | 765
astrocytoma 2 | 1,146
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
non primary Sjogren syndrome sicca 2 | 891
posterior fossa group B ependymoma 2 | 416
transitional cell carcinoma 2 | 22
Abnormality of retinal pigmentation 1 | 111
Autosomal recessive limb-girdle muscular dystrophy type 2A 1 | 4
Bladder Neoplasm 1 | 112
Blind Vision 1 | 111
Blindness, Legal 1 | 110
Breast Neoplasms 1 | 445
Carcinoma, Transitional Cell 1 | 32
Conductive hearing loss 1 | 123
MYH-9 related disease 1 | 12
Mammary Neoplasms 1 | 425
Ophthalmoplegia 1 | 106
Retinal pigment epithelial abnormality 1 | 111
Right atrial isomerism 1 | 29
Sensorineural Hearing Loss (disorder) 1 | 284
Systemic lupus erythematosus 1 | 194
Thrombocytopenia 1 | 197
Urinary Bladder Neoplasms 1 | 114

Tissue

Blood and immune system 25 | 16,909
Cardiovascular System 25 | 15,192
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678

Target Family

Non-IDG 17 | 12,091
Kinase 4 | 634
Enzyme 2 | 4,145
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

GO Process

spindle assembly 25 | 25
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HAUS augmin-like complex subunit 2 HAUS2 Tbio Non-IDG 0.71 0.12 44
HAUS augmin-like complex subunit 5 HAUS5 Tbio Non-IDG 0.34 0.65 77
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.19489 157.7 218
HAUS augmin-like complex subunit 6 HAUS6 Tbio Non-IDG -0.73970 5.75 70
HAUS augmin-like complex subunit 4 HAUS4 Tbio Non-IDG 0.34 0.27 91
Centrosomal protein of 192 kDa CEP192 Tbio Non-IDG -1.15560 13.3 34
StAR-related lipid transfer protein 9 STARD9 Tbio Non-IDG -0.69167 5.48 21
Serine/threonine-protein kinase Nek7 NEK7 Tchem Kinase -1.31475 20.8 261
HAUS augmin-like complex subunit 3 HAUS3 Tbio Non-IDG -2.19985 145.0 90
Centrosomal protein of 63 kDa CEP63 Tbio Non-IDG -1.75874 45.6 110