Development Level

Tchem 6 | 1,598
Tbio 2 | 11,445

IMPC Phenotype

abnormal hair growth 1 | 10
decreased circulating glucose ... 1 | 126

Disease

Carcinoma 5 | 11,493
psoriasis 4 | 6,694
tuberculosis 4 | 2,010
Farber lipogranulomatosis 3 | 9
Posterior amorphous corneal dystrophy 3 | 9
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
Cancer 2 | 2,499
Congenital pes cavus 2 | 88
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Distal sensory impairment 2 | 52
Distal sensory impairment of all modalities 2 | 7
Hereditary Sensory Autonomic Neuropathy, Type 1 2 | 4
Multiple Sclerosis 2 | 540
Multiple myeloma 2 | 1,332
Neurodegenerative disease 2 | 414
Neuropathy 2 | 261
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
medulloblastoma, large-cell 2 | 6,241
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
Abnormal respiratory patterns 1 | 20
Abnormality of aortic arch 1 | 9
Anhidrosis 1 | 23
Aortic calcification 1 | 2
Apathy 1 | 16
Aseptic Necrosis of Bone 1 | 8
Aseptic necrosis 1 | 8
Atrophoderma maculatum 1 | 4
Autoamputation of foot 1 | 2
Autosomal dominant late onset Parkinson disease 1 | 7
Bone disease 1 | 10
Bone infarction 1 | 8
Bone necrosis 1 | 9
Bulbar signs 1 | 4
Chronic axonal neuropathy 1 | 2
Colitis, Ulcerative 1 | 59
Collapse of vertebra 1 | 14
Compression fracture of vertebral column 1 | 14
Congenital Nonbullous Ichthyosiform Erythroderma 1 | 16
Coughing 1 | 25
Decrease in jaw opening 1 | 5
Delayed Puberty 1 | 97
Depletion of large myelinated fibers 1 | 7
Desquamation of skin soon after birth 1 | 10
Drooping upper lip 1 | 4
Dysesthesia 1 | 6
Ectropion 1 | 38
Erlenmeyer flask femora 1 | 4
Everted lower lip vermilion 1 | 54
Everted upper lip vermilion 1 | 4
Gaucher Disease 1 | 4
Globulin gamma serum plasma increased result 1 | 9
Horizontal Nystagmus 1 | 10
Hydrops Fetalis 1 | 21
Hydrops Fetalis, Non-Immune 1 | 8
Hypergammaglobulinemia 1 | 10
Hyperglobulinemia 1 | 9
Hyperkyphosis 1 | 111
Hypertension, Pulmonary 1 | 37
Idiopathic pulmonary arterial hypertension 1 | 40
Infarction, Middle Cerebral Artery 1 | 33
Infection of bone 1 | 19
Kyphosis deformity of spine 1 | 114
Lewy Body Disease 1 | 21
Lewy body dementia 1 | 4
Limited jaw mobility 1 | 5
Limited jaw opening 1 | 5
Lumbosacral lipoma 1 | 3
Lung Diseases, Interstitial 1 | 5
Memory Disorders 1 | 40
Movement disease 1 | 11
Muscle Rigidity 1 | 49
Neonatal Death 1 | 14
Opisthotonus 1 | 14
Osteomyelitis or necrosis, distal, due to sensory neuropathy (feet) 1 | 2
Osteosclerosis 1 | 31
PARKINSON DISEASE, LATE-ONSET 1 | 20
Paraparesis, Spastic 1 | 16
Partial fetal alcohol syndrome 1 | 6
Petechiae 1 | 13
Plasmacytoma 1 | 7
Protruding lower lip 1 | 54
Protruding upper lip 1 | 4
Protuberant abdomen 1 | 16
Raised level of immunoglobulins NOS 1 | 9
Recurrent aspiration pneumonia 1 | 4
Reticulate hyperpigmentation 1 | 5
Skin Abnormalities 1 | 37
Stillbirth 1 | 17
Tabes dorsalis 1 | 6
Trismus 1 | 6
Vascular Calcification 1 | 3
gamma globulins increased 1 | 9

Tissue

Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Skin and soft tissues 8 | 17,230
Cardiovascular System 7 | 15,192
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Urinary Tract 7 | 16,678

Target Family

Enzyme 6 | 4,145
Kinase 2 | 634

GO Process

sphingosine biosynthetic proce... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alkaline ceramidase 3 ACER3 Tbio Enzyme -2.07938 117.1 95
Serine palmitoyltransferase 1 SPTLC1 Tchem Enzyme -2.16711 143.2 285
Alkaline ceramidase 2 ACER2 Tchem Enzyme -1.05443 10.8 46
Alkaline ceramidase 1 ACER1 Tbio Enzyme -0.89946 7.07 114
Glucosylceramidase GBA Tchem Enzyme -3.22080 1617.1 299
Sphingosine kinase 1 SPHK1 Tchem Kinase -2.72994 583.6 518
Serine palmitoyltransferase 2 SPTLC2 Tchem Enzyme -1.70805 49.3 203
Sphingosine kinase 2 SPHK2 Tchem Kinase -2.21878 154.9 314