Development Level

Tchem 2 | 1,598

Disease

Carcinoma 2 | 11,493
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Distal sensory impairment 2 | 52
Distal sensory impairment of all modalities 2 | 7
Hereditary Sensory Autonomic Neuropathy, Type 1 2 | 4
Neuropathy 2 | 261
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Alopecia universalis 1 | 16
Alzheimer's disease 1 | 658
Anhidrosis 1 | 23
Aortic Valve Insufficiency 1 | 40
Astrocytoma, Pilocytic 1 | 3,081
Autoamputation 1 | 2
Autoamputation of foot 1 | 2
Bipolar Disorder 1 | 666
Chronic axonal neuropathy 1 | 2
Congenital pes cavus 1 | 88
Decreased sensory nerve conduction velocities (NCV) 1 | 8
Decreased tendon reflex 1 | 122
Depletion of large myelinated fibers 1 | 7
Dermatologic disorders 1 | 93
Dysesthesia 1 | 6
Foot Deformities 1 | 30
Hereditary sensory and autonomic neuropathy type IC 1 | 1
Infection of bone 1 | 19
Lumbosacral lipoma 1 | 3
Multiple Sclerosis 1 | 540
Multiple myeloma 1 | 1,332
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IA 1 | 1
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IC 1 | 1
Neurodegenerative disease 1 | 414
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Neuropathy, Hereditary Sensory and Autonomic, Type 1A 1 | 1
Osteomyelitis 1 | 42
Osteomyelitis or necrosis, distal, due to sensory neuropathy (feet) 1 | 2
Peripheral sensorimotor neuropathy 1 | 16
Reflex, Deep Tendon, Absent 1 | 92
Sensorineural Hearing Loss (disorder) 1 | 284
Skeletal muscle atrophy 1 | 139
Skin Abnormalities 1 | 37
Skin Ulcer 1 | 48
Tabes dorsalis 1 | 6
acute quadriplegic myopathy 1 | 1,158
adult high grade glioma 1 | 3,801
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
atypical teratoid / rhabdoid tumor 1 | 5,112
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
cutaneous lupus erythematosus 1 | 1,057
glioblastoma 1 | 5,792
group 4 medulloblastoma 1 | 1,855
hepatocellular carcinoma 1 | 547
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
medulloblastoma, large-cell 1 | 6,241
muscle degeneration 1 | 139
non-small cell lung cancer 1 | 2,890
osteosarcoma 1 | 7,950
pancreatic cancer 1 | 2,398
primary pancreatic ductal adenocarcinoma 1 | 1,109
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 2 | 4,145

GO Process

sphinganine biosynthetic proce... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine palmitoyltransferase 1 SPTLC1 Tchem Enzyme -2.16711 143.2 285
Serine palmitoyltransferase 2 SPTLC2 Tchem Enzyme -1.70805 49.3 203