Development Level

Tbio 236 | 11,178
Tdark 90 | 6,569
Tchem 51 | 1,885
Tclin 12 | 612

Collection

Kinase: IDG Consortium (Target... 6 | 125
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, incomple... 18 | 499
preweaning lethality, complete... 14 | 979
male infertility 13 | 123
enlarged heart 9 | 210
abnormal embryo size 8 | 220
embryonic lethality prior to t... 8 | 278
abnormal behavior 7 | 298
abnormal heart morphology 6 | 162
abnormal seminal vesicle morph... 6 | 114
decreased vertical activity 6 | 208
small testis 6 | 58
female infertility 5 | 60
hyperactivity 5 | 148
impaired glucose tolerance 5 | 75
increased bone mineral content 5 | 108
abnormal bone structure 4 | 187
embryonic growth retardation 4 | 106
embryonic lethality prior to o... 4 | 239
increased circulating HDL chol... 4 | 80
increased circulating alkaline... 4 | 122
thrombocytopenia 4 | 56
decreased body length 3 | 101
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
increased grip strength 3 | 41
prenatal lethality prior to he... 3 | 87
abnormal craniofacial morpholo... 2 | 33
abnormal embryo turning 2 | 31
abnormal liver morphology 2 | 17
abnormal pericardium morpholog... 2 | 26
abnormal spleen morphology 2 | 55
abnormal testis morphology 2 | 43
anophthalmia 2 | 33
decreased blood urea nitrogen ... 2 | 51
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating phosphat... 2 | 27
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased hemoglobin content 2 | 68
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
edema 2 | 59
hypoactivity 2 | 132
increased circulating triglyce... 2 | 42
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 36
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
increased total body fat amoun... 2 | 134
prolonged ST segment 2 | 36
shortened RR interval 2 | 17
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal epididymis morphology 1 | 42
abnormal esophagus morphology 1 | 5
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal heart looping 1 | 5
abnormal locomotor activation 1 | 16
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal tail movements 1 | 12
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased caudal vertebrae num... 1 | 53
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased pulmonary respirator... 1 | 5
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
limb grasping 1 | 41
long tibia 1 | 25
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
small kidney 1 | 16
small spleen 1 | 19
urinary bladder obstruction 1 | 4

Disease

Carcinoma 227 | 11,192
ovarian cancer 164 | 8,297
osteosarcoma 155 | 7,766
psoriasis 144 | 6,514
medulloblastoma, large-cell 130 | 6,086
glioblastoma 108 | 5,635
group 3 medulloblastoma 97 | 4,002
atypical teratoid / rhabdoid tumor 95 | 4,971
lung cancer 90 | 4,607
ependymoma 84 | 4,559
Cancer 75 | 2,388
Breast cancer 72 | 3,469
Kidney cancer 69 | 2,548
malignant mesothelioma 65 | 3,135
adult high grade glioma 61 | 3,701
primitive neuroectodermal tumor 61 | 2,957
intraductal papillary-mucinous neoplasm (IPMN) 57 | 3,204
non-small cell lung cancer 57 | 2,799
Male infertility 51 | 199
intraductal papillary-mucinous adenoma (IPMA) 51 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 51 | 2,902
lung adenocarcinoma 50 | 2,627
oligodendroglioma 47 | 2,768
Infertility 44 | 176
invasive ductal carcinoma 44 | 2,867
astrocytic glioma 42 | 2,530
Astrocytoma, Pilocytic 40 | 3,006
pancreatic cancer 39 | 2,322
pituitary cancer 33 | 1,915
breast carcinoma 32 | 1,589
colon cancer 32 | 1,428
lung carcinoma 32 | 2,755
Autosomal recessive predisposition 31 | 1,407
diabetes mellitus 31 | 1,683
ulcerative colitis 31 | 1,765
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,911
subependymal giant cell astrocytoma 30 | 2,230
tuberculosis 30 | 1,963
ductal carcinoma in situ 29 | 1,686
interstitial cystitis 29 | 2,237
Azoospermia 28 | 106
Schizophrenia 28 | 1,136
group 4 medulloblastoma 28 | 1,806
adrenocortical carcinoma 25 | 1,385
Pick disease 24 | 1,856
cutaneous lupus erythematosus 24 | 1,016
nasopharyngeal carcinoma 23 | 1,024
acute quadriplegic myopathy 22 | 1,133
Endometriosis 21 | 521
juvenile dermatomyositis 21 | 1,147
Cryptorchidism 20 | 287
Multiple myeloma 20 | 1,296
astrocytoma 19 | 1,113
cystic fibrosis 19 | 1,629
Intellectual disability 18 | 998
Melanoma 18 | 689
Rheumatoid arthritis 18 | 1,156
dermatomyositis 18 | 941
pediatric high grade glioma 18 | 1,035
spina bifida 18 | 1,053
Atopic dermatitis 17 | 915
Bipolar Disorder 17 | 646
Obesity 17 | 655
Skin cancer 16 | 451
non primary Sjogren syndrome sicca 16 | 861
primary pancreatic ductal adenocarcinoma 16 | 1,071
Alzheimer's disease 15 | 640
Liver cancer 15 | 589
Breast Neoplasms 14 | 423
Mammary Neoplasms 14 | 403
Hypogonadism 13 | 169
Prostatic Neoplasms 13 | 472
Short stature 13 | 514
acute myeloid leukemia 13 | 760
Dull intelligence 12 | 634
Liver Cirrhosis, Experimental 12 | 733
Low intelligence 12 | 634
Mental Retardation 12 | 634
Mental deficiency 12 | 634
Pancreatic Neoplasms 12 | 82
Polycystic ovary syndrome 12 | 348
Poor school performance 12 | 634
medulloblastoma 12 | 702
primary Sjogren syndrome 12 | 710
Cognitive delay 11 | 596
Global developmental delay 11 | 596
Mental and motor retardation 11 | 596
Pancreatic Neoplasm 11 | 82
gastric carcinoma 11 | 781
hepatocellular carcinoma 11 | 536
pancreatic carcinoma 11 | 555
posterior fossa group B ependymoma 11 | 406
Congenital hypoplasia of penis 10 | 168
Small head 10 | 366
Waldenstrons macroglobulinemia 10 | 742
aldosterone-producing adenoma 10 | 646
chronic rhinosinusitis 10 | 505
fibroadenoma 10 | 538
posterior fossa group A ependymoma 10 | 456
sonic hedgehog group medulloblastoma 10 | 459

Tissue

Endocrine System 379 | 18,159
Male tissues 326 | 17,142
Digestive Tract 325 | 17,369
Female tissues 325 | 17,400
Skin and soft tissues 318 | 17,230
Blood and immune system 312 | 16,909
Nervous System 305 | 16,725
Liver and Pancreas 303 | 16,750
Urinary Tract 303 | 16,678
Respiratory system 298 | 16,393
Cardiovascular System 262 | 15,192

Target Family

Non-IDG 230 | 12,091
Enzyme 56 | 4,145
Transcription Factor 37 | 1,400
Kinase 19 | 634
Epigenetic 18 | 242
GPCR 10 | 408
Transporter 7 | 473
Nuclear Receptor 5 | 48
TF/Epigenetic 4 | 38
Ion Channel 2 | 344
oGPCR 1 | 421

GO Process

spermatogenesis 389 | 389
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-Jun-amino-terminal kinase-interacting protein 4 SPAG9 Tbio Enzyme -2.45490 258.6 149
Ankycorbin RAI14 Tdark Non-IDG -1.33275 19.5 49
MYCBP-associated protein MYCBPAP Tbio Non-IDG 0.00000 37
Putative spermatogenesis-associated protein 31D3 SPATA31D3 Tdark Non-IDG 0.00000 0
GATA-type zinc finger protein 1 ZGLP1 Tdark Transcription Factor -0.45230 2.67 96
Nuclear transition protein 2 TNP2 Tbio Non-IDG -1.77298 56.6 86
Probable ubiquitin carboxyl-terminal hydrolase FAF-Y USP9Y Tbio Enzyme -1.52317 31.8 27
Protein SIX6OS1 C14orf39 Tdark Non-IDG 0.30 0.90 6
AT-rich interactive domain-containing protein 4B ARID4B Tbio TF/Epigenetic -1.25831 18.5 133
Nuclear receptor subfamily 6 group A member 1 NR6A1 Tbio Nuclear Receptor -2.36193 227.5 236