Development Level

Tbio 216 | 10,625
Tdark 89 | 7,003
Tchem 49 | 1,890
Tclin 11 | 602

Collection

Eligible Kinase Proteins 6 | 134
Eligible Ion Channel Proteins 1 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, incomple... 12 | 260
preweaning lethality, complete... 9 | 633
abnormal embryo size 6 | 112
abnormal behavior 5 | 226
male infertility 5 | 62
decreased lean body mass 4 | 195
embryonic lethality prior to t... 4 | 187
enlarged heart 4 | 111
hyperactivity 4 | 108
small testis 4 | 37
thrombocytopenia 4 | 46
abnormal seminal vesicle morph... 3 | 47
decreased body weight 3 | 174
decreased circulating triglyce... 3 | 83
decreased grip strength 3 | 123
increased circulating HDL chol... 3 | 63
increased grip strength 3 | 83
increased or absent threshold ... 3 | 128
abnormal embryo turning 2 | 15
abnormal eye morphology 2 | 38
abnormal heart morphology 2 | 51
abnormal pericardium morpholog... 2 | 11
abnormal retinal pigmentation 2 | 61
anophthalmia 2 | 20
decreased CD8-positive, alpha-... 2 | 26
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased caudal vertebrae num... 2 | 49
decreased circulating glucose ... 2 | 121
decreased circulating insulin ... 2 | 75
decreased effector memory CD8-... 2 | 24
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular vol... 2 | 50
embryonic growth retardation 2 | 28
embryonic lethality prior to o... 2 | 148
female infertility 2 | 34
impaired glucose tolerance 2 | 52
increased body weight 2 | 42
increased exploration in new e... 2 | 56
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular hem... 2 | 25
increased sacral vertebrae num... 2 | 62
abnormal allantois morphology 1 | 3
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal craniofacial morpholo... 1 | 12
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal heart looping 1 | 2
abnormal iris morphology 1 | 12
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal tail bud morphology 1 | 6
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 17
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
craniofacial phenotype 1 | 9
decreased CD4-positive, CD25-p... 1 | 24
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased mature B cell number 1 | 25
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating glucose ... 1 | 16
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased mean corpuscular vol... 1 | 91
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
limb grasping 1 | 35
long tibia 1 | 13
microphthalmia 1 | 15
narrow eye opening 1 | 15
pallor 1 | 13
persistence of hyaloid vascula... 1 | 22
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
shortened ST segment 1 | 9
small superior vagus ganglion 1 | 20
urinary bladder obstruction 1 | 2

Disease

ovarian cancer 152 | 8,484
osteosarcoma 146 | 7,933
psoriasis 136 | 6,685
medulloblastoma, large-cell 125 | 6,234
glioblastoma 105 | 5,572
lung cancer 89 | 4,466
atypical teratoid / rhabdoid tumor 79 | 4,369
Cancer 73 | 2,346
malignant mesothelioma 64 | 3,162
Breast cancer 62 | 3,094
primitive neuroectodermal tumor 58 | 3,031
Carcinoma 56 | 2,147
non-small cell lung cancer 55 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 54 | 3,289
lung adenocarcinoma 52 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 51 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 48 | 2,988
group 3 medulloblastoma 47 | 2,254
invasive ductal carcinoma 43 | 2,950
pediatric high grade glioma 43 | 2,712
Infertility 42 | 163
pilocytic astrocytoma 42 | 3,086
Male infertility 41 | 170
group 4 medulloblastoma 41 | 1,875
oligodendroglioma 41 | 2,849
posterior fossa group B ependymoma 41 | 1,530
ependymoma 36 | 2,514
pituitary cancer 36 | 1,972
adult high grade glioma 35 | 2,148
astrocytic glioma 35 | 2,241
ulcerative colitis 34 | 2,087
lung carcinoma 33 | 2,844
pancreatic cancer 33 | 2,300
subependymal giant cell astrocytoma 31 | 2,287
breast carcinoma 30 | 1,614
colon cancer 30 | 1,475
ductal carcinoma in situ 28 | 1,745
interstitial cystitis 28 | 2,299
medulloblastoma 28 | 1,524
adrenocortical carcinoma 26 | 1,427
sonic hedgehog group medulloblastoma 26 | 1,482
diabetes mellitus 25 | 1,663
nasopharyngeal carcinoma 24 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
tuberculosis 24 | 1,557
Pick disease 23 | 1,893
posterior fossa group A ependymoma 23 | 1,511
Endometriosis 22 | 535
acute quadriplegic myopathy 22 | 1,157
atypical teratoid/rhabdoid tumor 22 | 1,095
astrocytoma 21 | 1,493
cutaneous lupus erythematosus 21 | 1,056
juvenile dermatomyositis 21 | 1,189
Azoospermia 20 | 89
cystic fibrosis 20 | 1,665
Rheumatoid Arthritis 18 | 1,160
Multiple myeloma 17 | 1,327
dermatomyositis 17 | 933
non primary Sjogren syndrome sicca 17 | 840
primary pancreatic ductal adenocarcinoma 17 | 1,271
Atopic dermatitis 16 | 944
acute myeloid leukemia 15 | 780
spina bifida 15 | 1,064
Obesity 14 | 616
Mammary Neoplasms 13 | 410
Prostatic Neoplasms 13 | 471
pancreatic carcinoma 13 | 567
Alzheimer's disease 12 | 644
Cryptorchidism 12 | 67
aldosterone-producing adenoma 11 | 664
chronic rhinosinusitis 11 | 512
fibroadenoma 11 | 557
gastric carcinoma 11 | 832
hepatocellular carcinoma 11 | 532
primary Sjogren syndrome 11 | 789
tuberculosis and treatment for 6 months 11 | 686
Gonadoblastoma 10 | 27
Intellectual disability 10 | 573
Melanoma 10 | 261
Peripheral Neuropathy 10 | 303
Primary ciliary dyskinesia 10 | 73
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 499
Adenoma 9 | 165
Oligospermia 9 | 30
Pancreatic Neoplasm 9 | 79
Schizophrenia 9 | 501
Craniofacial Abnormalities 8 | 147
Duchenne muscular dystrophy 8 | 602
Liver carcinoma 8 | 217
Neurodegenerative disease 8 | 383
Sertoli cell-only syndrome 8 | 36
Waldenstrons macroglobulinemia 8 | 765
active Crohn's disease 8 | 918
esophageal adenocarcinoma 8 | 737
facioscapulohumeral dystrophy 8 | 286
tuberculosis and treatment for 3 months 8 | 327
Amyotrophic Lateral Sclerosis 7 | 431
IGA Glomerulonephritis 7 | 454
Multiple Sclerosis 7 | 498
mucosa-associated lymphoid tissue lymphoma 7 | 480

Tissue

Endocrine System 352 | 18,512
Female tissues 352 | 18,647
Male tissues 352 | 17,969
Digestive Tract 348 | 18,473
Nervous System 346 | 18,561
Blood and immune system 338 | 17,995
Urinary Tract 338 | 18,444
Cardiovascular System 335 | 17,958
Liver and Pancreas 333 | 18,136
Skin and soft tissues 329 | 18,115
Respiratory system 315 | 17,484

Target Family

Non-IDG 212 | 11,971
Enzyme 53 | 4,146
Transcription Factor 37 | 1,400
Epigenetic 18 | 242
Kinase 17 | 634
GPCR 9 | 406
Transporter 7 | 473
Nuclear Receptor 5 | 48
TF/Epigenetic 4 | 38
Ion Channel 2 | 341
oGPCR 1 | 421

GO Process

spermatogenesis 365 | 365
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Testis-specific gene 10 protein TSGA10 Tbio Non-IDG -1.05563 13.1 82
Ropporin-1B ROPN1B Tbio Non-IDG 1.00 0.10 52
Beta-1,4 N-acetylgalactosaminyltransferase 1 B4GALNT1 Tbio Enzyme -1.85387 67.6 146
Testicular spindle-associated protein SHCBP1L SHCBP1L Tdark Non-IDG -0.52288 3.33 25
Spermatogenesis-associated protein 5 SPATA5 Tchem Enzyme -2.14514 137.7 23
Meiosis-specific nuclear structural protein 1 MNS1 Tbio Non-IDG -1.16311 14.2 55
Transcriptional repressor protein YY1 YY1 Tbio Transcription Factor -2.75991 594.0 437
Bromodomain-containing protein 2 BRD2 Tchem Epigenetic -2.42927 0.00000 306
Golgin subfamily A member 3 GOLGA3 Tbio Non-IDG -1.29668 20.3 130