Development Level

Tbio 52 | 10,625
Tdark 16 | 7,003
Tchem 3 | 1,890
Tclin 1 | 602

Collection

Kinase: IDG Consortium (Complete/Control) 1 | 37
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 3 | 260
abnormal behavioral response t... 2 | 52
male infertility 2 | 62
abnormal cranium morphology 1 | 32
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal retinal pigmentation 1 | 61
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 35
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 24
decreased circulating chloride... 1 | 32
decreased circulating glucose ... 1 | 121
decreased heart rate variabili... 1 | 11
decreased lean body mass 1 | 195
decreased mean corpuscular vol... 1 | 50
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
excessive tearing 1 | 2
female infertility 1 | 34
increased blood urea nitrogen ... 1 | 44
increased exploration in new e... 1 | 56
increased heart rate 1 | 17
increased leukocyte cell numbe... 1 | 37
short tibia 1 | 82
shortened RR interval 1 | 19
shortened ST segment 1 | 9
thin tail 1 | 1

Disease

medulloblastoma, large-cell 29 | 6,234
ovarian cancer 27 | 8,491
glioblastoma 25 | 5,572
osteosarcoma 24 | 7,933
psoriasis 24 | 6,685
atypical teratoid / rhabdoid tumor 21 | 4,369
lung cancer 17 | 4,473
Breast cancer 16 | 3,098
Male infertility 16 | 170
ependymoma 14 | 2,514
invasive ductal carcinoma 14 | 2,950
pediatric high grade glioma 14 | 2,712
pilocytic astrocytoma 13 | 3,086
primitive neuroectodermal tumor 13 | 3,031
Carcinoma 12 | 2,147
ductal carcinoma in situ 11 | 1,745
group 4 medulloblastoma 11 | 1,875
lung adenocarcinoma 11 | 2,714
malignant mesothelioma 11 | 3,163
non-small cell lung cancer 11 | 2,798
posterior fossa group B ependymoma 11 | 1,530
Cancer 10 | 2,346
astrocytic glioma 10 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
medulloblastoma 10 | 1,524
subependymal giant cell astrocytoma 10 | 2,287
Infertility 9 | 163
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
lung carcinoma 9 | 2,844
oligodendroglioma 9 | 2,849
pancreatic cancer 9 | 2,300
ulcerative colitis 9 | 2,087
Multiple myeloma 8 | 1,327
colon cancer 8 | 1,475
group 3 medulloblastoma 8 | 2,254
interstitial cystitis 8 | 2,299
nasopharyngeal carcinoma 8 | 1,056
atypical teratoid/rhabdoid tumor 7 | 1,095
breast carcinoma 7 | 1,614
chronic rhinosinusitis 7 | 512
pituitary cancer 7 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
Obesity 5 | 616
Primary ciliary dyskinesia 5 | 75
Waldenstrons macroglobulinemia 5 | 764
aldosterone-producing adenoma 5 | 664
cystic fibrosis 5 | 1,670
dermatomyositis 5 | 966
mucosa-associated lymphoid tissue lymphoma 5 | 480
pancreatic carcinoma 5 | 567
progressive supranuclear palsy 5 | 674
Down syndrome 4 | 548
Intellectual disability 4 | 573
Melanoma 4 | 261
Pick disease 4 | 1,893
Rheumatoid Arthritis 4 | 1,170
Varicocele 4 | 21
adult high grade glioma 4 | 2,148
cutaneous lupus erythematosus 4 | 1,056
non primary Sjogren syndrome sicca 4 | 840
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
sonic hedgehog group medulloblastoma 4 | 1,482
spina bifida 4 | 1,064
tuberculosis and treatment for 6 months 4 | 686
Parkinson's disease 3 | 364
Polydactyly 3 | 93
active Crohn's disease 3 | 918
adrenocortical carcinoma 3 | 1,427
non-small cell lung carcinoma 3 | 413
posterior fossa group A ependymoma 3 | 1,511
tuberculosis 3 | 1,563
Alzheimer's disease 2 | 644
Anemia 2 | 252
Atopic dermatitis 2 | 944
Dementia 2 | 129
Endometriosis 2 | 535
Fanconi's anemia 2 | 50
Ganglioglioma 2 | 16
Gaucher disease type 1 2 | 171
Hydrocephalus 2 | 60
Hypogonadism 2 | 70
Lung diseases 2 | 48
Microcephaly 2 | 149
Progressive relapsing multiple sclerosis 2 | 18
Retinitis pigmentosa 2 | 156
Schizophrenia 2 | 503
Situs Inversus 2 | 52
Skin cancer 2 | 37
Testicular germ cell tumor 2 | 23
acute quadriplegic myopathy 2 | 1,157
astrocytoma 2 | 1,493
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 557
gastric cancer 2 | 436
glioblastoma multiforme 2 | 347
hepatocellular carcinoma 2 | 550
hereditary spastic paraplegia 2 | 313
primary Sjogren syndrome 2 | 788
primary pancreatic ductal adenocarcinoma 2 | 1,271
tuberculosis and treatment for 3 months 2 | 327

Tissue

Endocrine System 70 | 18,511
Male tissues 70 | 17,968
Female tissues 69 | 18,646
Liver and Pancreas 68 | 18,135
Nervous System 68 | 18,560
Urinary Tract 68 | 18,443
Cardiovascular System 67 | 17,957
Digestive Tract 67 | 18,472
Skin and soft tissues 67 | 18,114
Blood and immune system 66 | 17,994
Respiratory system 64 | 17,483

Target Family

Non-IDG 47 | 11,969
Enzyme 12 | 4,146
Kinase 6 | 634
Epigenetic 4 | 242
Transcription Factor 3 | 1,400

GO Process

spermatid development 72 | 72
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein quaking QKI Tbio Non-IDG -1.81649 63.7 254
Insulin-like peptide INSL6 INSL6 Tdark Non-IDG -1.08799 12.2 31
Testis-specific serine/threonine-protein kinase 1 TSSK1B Tchem Kinase -1.41882 23.1 26
RING finger protein 17 RNF17 Tdark Epigenetic -0.94706 8.25 45
Spermatid perinuclear RNA-binding protein STRBP Tdark Non-IDG -1.83687 66.9 35
Desert hedgehog protein DHH Tbio Non-IDG -2.22195 152.9 260
Junctional adhesion molecule C JAM3 Tbio Non-IDG -1.89346 55.4 183
Radial spoke head 1 homolog RSPH1 Tbio Non-IDG -1.29320 18.8 46
Putative C-mannosyltransferase DPY19L2P2 DPY19L2P2 Tdark Enzyme -1.78929 114.3 0
Pachytene checkpoint protein 2 homolog TRIP13 Tbio Enzyme -1.85185 73.9 197