Development Level

Tbio 35 | 11,445
Tchem 7 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal limb morphology 2 | 13
increased monocyte cell number 2 | 63
abnormal body wall morphology 1 | 9
abnormal eating behavior 1 | 1
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal forced expiratory flo... 1 | 1
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal retina morphology 1 | 71
abnormal tail morphology 1 | 25
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
anophthalmia 1 | 33
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating glycerol... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased tidal volume 1 | 1
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hemorrhage 1 | 23
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
microphthalmia 1 | 26
polydactyly 1 | 7
protruding tongue 1 | 3
respiratory system phenotype 1 | 2

Disease

Carcinoma 30 | 11,493
ovarian cancer 25 | 8,520
Cancer 18 | 2,499
osteosarcoma 18 | 7,950
psoriasis 18 | 6,694
medulloblastoma, large-cell 16 | 6,241
atypical teratoid / rhabdoid tumor 14 | 5,112
ependymoma 13 | 4,679
lung cancer 12 | 4,740
Breast cancer 10 | 3,578
Kidney cancer 10 | 2,613
astrocytic glioma 10 | 2,597
group 3 medulloblastoma 10 | 4,104
lung adenocarcinoma 10 | 2,716
malignant mesothelioma 10 | 3,232
Astrocytoma, Pilocytic 9 | 3,081
Autosomal recessive predisposition 9 | 1,442
adult high grade glioma 9 | 3,801
glioblastoma 9 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
pancreatic cancer 9 | 2,398
acute quadriplegic myopathy 8 | 1,158
breast carcinoma 8 | 1,638
invasive ductal carcinoma 8 | 2,951
Breast Neoplasms 7 | 445
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
Acquired scoliosis 6 | 281
Curvature of spine 6 | 282
Intellectual disability 6 | 1,016
Mammary Neoplasms 6 | 425
Pick disease 6 | 1,894
Short stature 6 | 531
Spondylocostal dysostosis 6 | 12
interstitial cystitis 6 | 2,312
juvenile dermatomyositis 6 | 1,187
primitive neuroectodermal tumor 6 | 3,035
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Cataract 5 | 297
Cognitive delay 5 | 608
Craniofacial Abnormalities 5 | 151
Dull intelligence 5 | 645
Endometrial cancer 5 | 311
Global developmental delay 5 | 608
Jarcho-Levin syndrome 5 | 5
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Patent ductus arteriosus 5 | 90
Poor school performance 5 | 645
Prostatic Neoplasms 5 | 495
Schizophrenia 5 | 1,160
Spondylocostal dysostosis, autosomal recessive 5 | 5
colon cancer 5 | 1,478
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic lateral sclerosis 4 | 451
Delayed bone age 4 | 136
Down syndrome 4 | 499
Epilepsy 4 | 792
Exophthalmos 4 | 112
Hypoplastic mandible condyle 4 | 275
Lens Opacities 4 | 231
Mandibular hypoplasia 4 | 275
Melanoma 4 | 711
Micrognathism 4 | 275
Multiple Sclerosis 4 | 540
Orbital separation excessive 4 | 244
Pectus excavatum 4 | 100
Prominent eyes 4 | 96
Prominent globes 4 | 96
Protruding eyes 4 | 96
Rheumatoid arthritis 4 | 1,191
Scoliosis 4 | 44
Seizures 4 | 596
Small head 4 | 374
Ventricular Septal Defects 4 | 119
aldosterone-producing adenoma 4 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
dermatomyositis 4 | 966
fibroadenoma 4 | 559
group 4 medulloblastoma 4 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
progressive supranuclear palsy 4 | 676
Failure to gain weight 3 | 365
Strabismus 3 | 270
Umbilical hernia 3 | 93
Waldenstrons macroglobulinemia 3 | 765
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
sonic hedgehog group medulloblastoma 3 | 467
spina bifida 3 | 1,074

Tissue

Digestive Tract 43 | 17,369
Endocrine System 41 | 18,159
Male tissues 39 | 17,142
Nervous System 39 | 16,725
Skin and soft tissues 39 | 17,230
Blood and immune system 37 | 16,909
Female tissues 36 | 17,400
Urinary Tract 36 | 16,678
Cardiovascular System 33 | 15,192
Liver and Pancreas 33 | 16,750
Respiratory system 33 | 16,393

Target Family

Transcription Factor 18 | 1,400
Non-IDG 14 | 12,091
Enzyme 5 | 4,145
Kinase 4 | 634
Epigenetic 2 | 242

GO Process

somitogenesis 43 | 43
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein C2 FOXC2 Tbio Transcription Factor -2.23435 187.0 419
Notchless protein homolog 1 NLE1 Tbio Non-IDG -2.69934 437.6 162
Forkhead box protein B1 FOXB1 Tbio Transcription Factor -1.17019 15.7 110
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
Mesoderm posterior protein 1 MESP1 Tbio Transcription Factor -1.38536 26.8 208
Transcription factor HES-7 HES7 Tbio Transcription Factor -1.36047 22.6 144
Transcription factor 15 TCF15 Tbio Transcription Factor -2.45759 267.3 70
E3 ubiquitin-protein ligase MIB1 MIB1 Tbio Enzyme -1.18767 13.9 219
Delta-like protein 3 DLL3 Tbio Non-IDG -1.68978 48.6 214
Protocadherin-8 PCDH8 Tbio Non-IDG -2.22282 170.9 95