Development Level

Tbio 55 | 11,445
Tchem 5 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased bone mineral density 2 | 126
decreased lean body mass 2 | 135
embryonic lethality prior to t... 2 | 278
increased total body fat amoun... 2 | 134
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal optic disc morphology 1 | 10
abnormal ovary morphology 1 | 7
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal snout morphology 1 | 23
abnormal tail movements 1 | 12
absent epididymis 1 | 3
corneal opacity 1 | 32
curly tail 1 | 1
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased hemoglobin content 1 | 68
decreased respiratory quotient 1 | 16
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
fused cornea and lens 1 | 5
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased or absent threshold ... 1 | 101
iris synechia 1 | 3
kinked tail 1 | 2
limb grasping 1 | 41
male infertility 1 | 123
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 37 | 11,493
ovarian cancer 34 | 8,520
Cancer 33 | 2,499
osteosarcoma 31 | 7,950
psoriasis 28 | 6,694
lung cancer 27 | 4,740
medulloblastoma, large-cell 23 | 6,241
glioblastoma 22 | 5,792
ependymoma 20 | 4,679
atypical teratoid / rhabdoid tumor 19 | 5,112
lung adenocarcinoma 18 | 2,716
invasive ductal carcinoma 17 | 2,951
oligodendroglioma 17 | 2,850
Breast cancer 16 | 3,578
malignant mesothelioma 16 | 3,232
Kidney cancer 15 | 2,613
group 3 medulloblastoma 15 | 4,104
non-small cell lung cancer 15 | 2,890
pituitary cancer 15 | 1,972
adult high grade glioma 14 | 3,801
astrocytic glioma 14 | 2,597
primitive neuroectodermal tumor 14 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
breast carcinoma 12 | 1,638
ductal carcinoma in situ 12 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
subependymal giant cell astrocytoma 12 | 2,287
Astrocytoma, Pilocytic 11 | 3,081
group 4 medulloblastoma 11 | 1,855
interstitial cystitis 11 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung carcinoma 11 | 2,843
Orbital separation excessive 10 | 244
Short stature 10 | 531
pancreatic cancer 10 | 2,398
Multiple myeloma 9 | 1,332
Rheumatoid arthritis 9 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
cystic fibrosis 9 | 1,696
tuberculosis 9 | 2,010
Cryptorchidism 8 | 296
acute quadriplegic myopathy 8 | 1,158
Craniofacial Abnormalities 7 | 151
Down syndrome 7 | 499
Failure to gain weight 7 | 365
Pediatric failure to thrive 7 | 365
Small head 7 | 374
Strabismus 7 | 270
adrenocortical carcinoma 7 | 1,428
astrocytoma 7 | 1,146
colon cancer 7 | 1,478
diabetes mellitus 7 | 1,728
ulcerative colitis 7 | 1,819
Breast Neoplasms 6 | 445
Broad flat nasal bridge 6 | 236
Cleft Palate 6 | 271
Congenital deafness 6 | 185
Deafness 6 | 198
Dull intelligence 6 | 645
Hearing Loss, Partial 6 | 185
Heart disease 6 | 306
Hydrocephalus 6 | 152
Hypoplastic mandible condyle 6 | 275
Intellectual disability 6 | 1,016
Low intelligence 6 | 645
Mammary Neoplasms 6 | 425
Mandibular hypoplasia 6 | 275
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Micrognathism 6 | 275
Muscle hypotonia 6 | 571
Nasal bridge wide 6 | 236
Poor school performance 6 | 645
Prostatic Neoplasms 6 | 495
acute myeloid leukemia 6 | 783
hearing impairment 6 | 199
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Acquired scoliosis 5 | 281
Adenoma 5 | 167
Alzheimer's disease 5 | 658
Bilateral fifth finger clinodactyly 5 | 110
Cognitive delay 5 | 608
Concave bridge of nose 5 | 195
Congenital Epicanthus 5 | 177
Curvature of little finger 5 | 110
Curvature of spine 5 | 282
Depressed nasal bridge 5 | 195
Depressed nasal root/bridge 5 | 195
Global developmental delay 5 | 608
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Low set ears 5 | 181
Mental and motor retardation 5 | 608
Pick disease 5 | 1,894
Seizures 5 | 596
Short neck 5 | 140
Ventricular Septal Defects 5 | 119
esophageal adenocarcinoma 5 | 737
juvenile dermatomyositis 5 | 1,187
pediatric high grade glioma 5 | 1,064

Tissue

Endocrine System 63 | 18,159
Skin and soft tissues 63 | 17,230
Digestive Tract 62 | 17,369
Male tissues 62 | 17,142
Female tissues 61 | 17,400
Liver and Pancreas 61 | 16,750
Urinary Tract 61 | 16,678
Blood and immune system 60 | 16,909
Nervous System 60 | 16,725
Respiratory system 58 | 16,393
Cardiovascular System 53 | 15,192

Target Family

Transcription Factor 26 | 1,400
Non-IDG 18 | 12,091
Enzyme 13 | 4,145
Kinase 4 | 634
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

GO Process

somatic stem cell population m... 64 | 64
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ETS-related transcription factor Elf-5 ELF5 Tbio Transcription Factor -1.72839 58.0 200
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.49730 299.8 149
Sal-like protein 4 SALL4 Tbio Transcription Factor -2.64737 454.3 165
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
Forkhead box protein D3 FOXD3 Tbio Transcription Factor -2.69659 482.7 180
Homeobox protein CDX-2 CDX2 Tbio Transcription Factor -2.91273 837.0 699
LIM domain-binding protein 1 LDB1 Tbio Non-IDG -2.22623 164.4 206
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
DNA-directed RNA polymerases I, II, and III subunit RPABC2 POLR2F Tbio Enzyme -1.13403 13.9 68
Zinc finger and SCAN domain-containing protein 10 ZSCAN10 Tdark Transcription Factor -0.86793 7.67 21