Development Level

Tbio 7 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal lens morphology 1 | 81
abnormal snout morphology 1 | 23
abnormal tail movements 1 | 12
abnormal vertebrae morphology 1 | 18
cataract 1 | 92
curly tail 1 | 1
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
increased blood urea nitrogen ... 1 | 48
kinked tail 1 | 2
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 8 | 11,493
Cancer 7 | 2,499
glioblastoma 7 | 5,792
Astrocytoma, Pilocytic 6 | 3,081
Breast cancer 6 | 3,578
astrocytic glioma 6 | 2,597
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung cancer 6 | 4,740
ovarian cancer 6 | 8,520
adult high grade glioma 5 | 3,801
medulloblastoma, large-cell 5 | 6,241
pituitary cancer 5 | 1,972
psoriasis 5 | 6,694
cystic fibrosis 4 | 1,696
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
osteosarcoma 4 | 7,950
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Breast Neoplasms 3 | 445
Immune system cancer 3 | 140
Lymphoid leukemia 3 | 160
Mammary Neoplasms 3 | 425
Mesothelioma, Malignant 3 | 105
Skin cancer 3 | 469
adrenocortical carcinoma 3 | 1,428
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
non-small cell lung carcinoma 3 | 317
Byzanthine arch palate 2 | 194
Carcinoma, Non-Small-Cell Lung 2 | 107
Carcinoma, Pancreatic Ductal 2 | 20
Carcinoma, Squamous Cell 2 | 110
Cataract 2 | 297
Claw hand 2 | 26
Craniofacial Abnormalities 2 | 151
Cutis marmorata 2 | 32
Esophageal Squamous Cell Carcinoma 2 | 77
Genitourinary Neoplasms 2 | 3
Glaucoma 2 | 239
Head and neck squamous cell carcinoma 2 | 11
Heart disease 2 | 306
Hydrocephalus 2 | 152
Kidney cancer 2 | 2,613
Liver cancer 2 | 604
Lymphoma 2 | 81
Melanoma 2 | 711
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2 | 25
Sarcoma 2 | 62
Squamous cell carcinoma of esophagus 2 | 77
Stomach Neoplasms 2 | 300
Upper respiratory tract disease 2 | 15
Urogenital Neoplasms 2 | 3
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
nasopharyngeal carcinoma 2 | 1,058
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
Abnormality of the tibia 1 | 9
Adams-Oliver syndrome 1 | 15
Angiomyolipoma 1 | 18
Aortic Aneurysm, Thoracic 1 | 8
Aortic Valve Disease 1 1 | 2
Aortic Valve, Calcification of 1 | 3
Aortic valve calcification 1 | 5
Aortic valve disorder 1 | 2
Aortic valve stenosis 1 | 28
Dystrophic toenail changes 1 | 12
Hajdu-Cheney syndrome 1 | 4
Hypoplastic iliac wing 1 | 19
Leukemia, T-Cell 1 | 5
Long ears 1 | 2
Macule 1 | 19
Medullary thyroid carcinoma 1 | 6
Melanoma-Astrocytoma Syndrome 1 | 2
Multiple, subcutaneous nodules 1 | 53
Neurofibromatoses 1 | 5
Phocomelia 1 | 2
Right Ventricular Hypertrophy 1 | 6
Short stature, disproportionate 1 | 9
Short stature, severe disproportionate 1 | 9
Smooth muscle tumor 1 | 13
Soft calvaria 1 | 8
Subcutaneous nodule 1 | 53
Teratoma 1 | 8
Thoracic aortic aneurysm 1 | 15

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Nervous System 8 | 16,725
Cardiovascular System 7 | 15,192

Target Family

Non-IDG 6 | 12,091
GPCR 1 | 408
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

somatic stem cell division 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mast/stem cell growth factor receptor Kit KIT Tclin Kinase -3.80501 6371.9 4098
mRNA decay activator protein ZFP36L2 ZFP36L2 Tbio Non-IDG -1.54477 30.6 140
Frizzled-7 FZD7 Tbio GPCR -1.81873 66.4 345
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Homeobox protein Hox-B4 HOXB4 Tbio Transcription Factor -2.16826 159.7 211
Vang-like protein 2 VANGL2 Tbio Non-IDG -2.29322 199.6 158
Neurogenic locus notch homolog protein 1 NOTCH1 Tchem Non-IDG -4.08071 11843.2 916
Protein Wnt-7a WNT7A Tbio Non-IDG -2.13600 138.3 124
Tumor suppressor ARF CDKN2A Tbio Non-IDG -3.72848 9058.6 1063