Development Level

Tbio 10 | 11,445
Tdark 5 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

male infertility 1 | 123
preweaning lethality, complete... 1 | 979
small testis 1 | 58

Disease

Cancer 13 | 2,499
ovarian cancer 12 | 8,520
Carcinoma 11 | 11,493
Lynch syndrome 8 | 35
Adenoma 7 | 167
Familial adenomatous polyposis 7 | 32
Sebaceous adenoma 7 | 26
glioblastoma 7 | 5,792
psoriasis 7 | 6,694
Autosomal recessive predisposition 5 | 1,442
group 3 medulloblastoma 5 | 4,104
lung cancer 5 | 4,740
medulloblastoma, large-cell 5 | 6,241
non-small cell lung cancer 5 | 2,890
osteosarcoma 5 | 7,950
Abdominal Pain 4 | 98
Abnormality of the abdomen 4 | 14
Anxiety 4 | 136
Anxiety disease 4 | 113
Attention deficit hyperactivity disorder 4 | 278
Axillary freckling 4 | 5
Basal cell carcinoma 4 | 54
Basal cell nevi 4 | 23
Birthmark 4 | 35
Breast cancer 4 | 3,578
Cafe-au-Lait Spots 4 | 37
Colorectal Neoplasms 4 | 243
Colorectal Neoplasms, Hereditary Nonpolyposis 4 | 9
Constipation 4 | 181
Death in early adulthood 4 | 24
Death in early childhood 4 | 82
Death in infancy 4 | 82
Depressive disorder 4 | 409
Dyschezia 4 | 135
Epilepsy 4 | 792
Fatigue 4 | 182
Gastrointestinal Hemorrhage 4 | 52
Hematologic Neoplasms 4 | 22
Hereditary Nonpolyposis Colorectal Cancer 4 | 11
Hereditary Nonpolyposis Colorectal Neoplasms 4 | 8
Hyperpigmented macules 4 | 42
Intermittent migraine headaches 4 | 68
Intracranial hypertension 4 | 32
Irritation - emotion 4 | 68
Leukemia 4 | 104
Lymphoma 4 | 81
Malabsorption 4 | 82
Malignant tumor of colon 4 | 19
Migraine Disorders 4 | 76
Muscle Hypertonia 4 | 88
Muscle hypotonia 4 | 571
Nausea and vomiting 4 | 97
Neuroblastoma 4 | 80
Rectal Neoplasms 4 | 18
Rhabdomyosarcoma 4 | 39
Seizures 4 | 596
Turcot syndrome 4 | 5
Turcot syndrome (disorder) 4 | 5
Weight decreased 4 | 103
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
medulloblastoma 4 | 720
Colorectal cancer 3 | 25
Fibrous skin tumor of tuberous sclerosis 3 | 18
Increased gastric cancer 3 | 21
Kidney cancer 3 | 2,613
Lynch Syndrome 1 3 | 4
Muir-Torre syndrome 3 | 4
Stomach Neoplasms 3 | 300
Torre-Muir syndrome 3 | 3
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
nasopharyngeal carcinoma 3 | 1,058
ovarian neoplasm 3 | 99
primitive neuroectodermal tumor 3 | 3,035
Adenocarcinoma of duodenum 2 | 2
Benign digestive system neoplasms 2 | 2
Cafe au lait spots, multiple 2 | 17
Colon diverticulum anatomic structure 2 | 15
Colonic Neoplasms 2 | 142
Diverticular disease of colon 2 | 15
Duodenal Cancer 2 | 2
Endometrial carcinoma 2 | 15
Hereditary nonpolyposis colorectal carcinoma 2 | 18
Hyper-IgM Immunodeficiency Syndrome 2 | 3
Hyperimmunoglobulin M syndrome 2 | 3
Neoplasm Metastasis 2 | 168
Ovarian Neoplasms 2 | 102
Pain agnosia 2 | 104
Sebaceous Adenocarcinoma 2 | 2
Xeroderma pigmentosum 2 | 43
acute myeloid leukemia 2 | 783
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Enzyme 13 | 4,145
Non-IDG 2 | 12,091
Epigenetic 1 | 242

GO Process

somatic hypermutation of immun... 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative postmeiotic segregation increased 2-like protein 1 PMS2P1 Tdark Enzyme -2.19299 339.5 0
Putative postmeiotic segregation increased 2-like protein 3 PMS2P3 Tdark Enzyme -2.19299 339.5 0
Putative postmeiotic segregation increased 2-like protein 2 PMS2P2 Tdark Enzyme 0.00000 0
Uracil-DNA glycosylase UNG Tbio Enzyme -2.82957 680.9 352
Putative postmeiotic segregation increased 2-like protein 11 PMS2P11 Tdark Enzyme -2.19299 339.5 0
Exonuclease 1 EXO1 Tbio Enzyme -2.64302 437.0 263
Postmeiotic segregation increased 2-like protein 5 PMS2P5 Tdark Enzyme 0.00000 0
DNA mismatch repair protein Msh6 MSH6 Tbio Epigenetic -2.72594 572.3 479
Single-stranded DNA cytosine deaminase AICDA Tbio Enzyme -2.85153 635.3 302
DNA polymerase theta POLQ Tbio Enzyme -1.61640 40.0 57