Development Level

Tclin 12 | 613
Tbio 10 | 11,445
Tchem 6 | 1,598

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
abnormal pelvic girdle bone mo... 1 | 12
abnormal sleep behavior 1 | 70
decreased body length 1 | 101
decreased circulating alkaline... 1 | 46
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 24 | 11,493
glioblastoma 15 | 5,792
medulloblastoma, large-cell 14 | 6,241
adult high grade glioma 13 | 3,801
atypical teratoid / rhabdoid tumor 13 | 5,112
ependymoma 13 | 4,679
osteosarcoma 13 | 7,950
ovarian cancer 12 | 8,520
Astrocytoma, Pilocytic 11 | 3,081
Kidney cancer 10 | 2,613
oligodendroglioma 10 | 2,850
group 3 medulloblastoma 9 | 4,104
lung carcinoma 9 | 2,843
primitive neuroectodermal tumor 9 | 3,035
Atrial Fibrillation 8 | 124
Epilepsy 8 | 792
astrocytic glioma 8 | 2,597
lung cancer 8 | 4,740
pituitary cancer 8 | 1,972
Breast cancer 7 | 3,578
Seizures 7 | 596
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
pancreatic cancer 7 | 2,398
psoriasis 7 | 6,694
Autosomal recessive predisposition 6 | 1,442
Brain Ischemia 6 | 110
Brugada syndrome 6 | 29
Kidney disease 6 | 430
Paroxysmal atrial fibrillation 6 | 14
Pick disease 6 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung adenocarcinoma 6 | 2,716
subependymal giant cell astrocytoma 6 | 2,287
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 5 | 21
Brugada Syndrome (disorder) 5 | 15
Edema 5 | 81
Familial atrial fibrillation 5 | 23
Hypertension 5 | 396
Hypertensive disorder 5 | 56
Infantile onset 5 | 238
Status Epilepticus 5 | 98
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
Administration of Corneal Anesthesia 4 | 6
Anesthesia for cesarean section 4 | 8
Bipolar disorder in remission 4 | 19
Constipation 4 | 181
Cough 4 | 23
Diarrhea 4 | 253
Dyschezia 4 | 135
Dysuria 4 | 26
Epilepsy characterized by intractable complex partial seizures 4 | 28
Heart conduction disease 4 | 83
Heart disease 4 | 306
Hemorrhoids 4 | 13
Infestation by Phthirus pubis 4 | 7
Infestation by Sarcoptes scabiei var hominis 4 | 7
Itching of skin 4 | 18
Lennox-Gastaut syndrome 4 | 34
Life-Threatening Ventricular Tachycardia 4 | 15
Liver cancer 4 | 604
Local Anesthesia for Endotracheal Intubation 4 | 6
Local Anesthesia for Ophthalmologic Procedure 4 | 7
Local Anesthesia for Urethral Pain 4 | 6
Local anesthesia 4 | 40
Local anesthetic intrathecal block 4 | 7
Localization-related epilepsy 4 | 13
Major Nerve Block for Surgery 4 | 8
Melanoma 4 | 711
Minor Skin Wound Pain 4 | 12
Motor cortex epilepsy 4 | 10
Mouth Irritation 4 | 12
Neuralgia 4 | 20
Partial seizure 4 | 15
Pediculosis capitis 4 | 7
Postherpetic neuralgia 4 | 11
Premature ejaculation 4 | 16
Prevent Minor Bacterial Skin Infection 4 | 10
Pruritus ani 4 | 14
Regional Anesthesia for Labor Pain 4 | 9
Regional Anesthesia for Ophthalmologic Surgery 4 | 6
Regional Anesthesia for Postoperative Pain 4 | 9
Regional Anesthesia for Surgery 4 | 9
Simple partial seizure 4 | 26
Skin cancer 4 | 469
Skin irritation 4 | 12
Sore throat symptom 4 | 12
Suppression of the Gag Reflex 4 | 12
Tinea Infections 4 | 10
Tinea pedis 4 | 29
Tonic-clonic epilepsy 4 | 47
Tonic-clonic seizure 4 | 11
Urethritis 4 | 10
Urinary Tract Irritation 4 | 24
Ventricular arrhythmia 4 | 27
nephrosclerosis 4 | 333
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962

Tissue

Endocrine System 28 | 18,159
Digestive Tract 25 | 17,369
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Urinary Tract 25 | 16,678
Respiratory system 24 | 16,393
Blood and immune system 23 | 16,909
Female tissues 22 | 17,400
Skin and soft tissues 22 | 17,230
Cardiovascular System 18 | 15,192

Target Family

Ion Channel 21 | 344
Transporter 7 | 473

GO Process

sodium ion transmembrane trans... 28 | 28
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.17690 1469.3 126
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 HCN2 Tclin Ion Channel -1.16715 13.3 162
Sodium-dependent phosphate transport protein 1 SLC17A1 Tbio Transporter -1.73498 53.1 39
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Tclin Ion Channel -2.48671 270.6 121
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Sodium channel subunit beta-4 SCN4B Tbio Ion Channel -1.42029 24.1 85
Solute carrier family 13 member 1 SLC13A1 Tbio Transporter -1.79319 70.9 21
Sodium/calcium exchanger 2 SLC8A2 Tbio Transporter -1.70924 45.0 59
Sodium-dependent phosphate transport protein 4 SLC17A3 Tbio Transporter -1.10877 13.3 46
Potassium channel subfamily K member 1 KCNK1 Tbio Ion Channel -1.91364 80.5 208