Development Level

Tclin 4 | 613
Tbio 3 | 11,445
Tchem 3 | 1,598
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal pelvic girdle bone mo... 1 | 12

Disease

Carcinoma 10 | 11,493
Hypertension 6 | 396
ovarian cancer 6 | 8,520
Kidney disease 5 | 430
interstitial cystitis 5 | 2,312
Autosomal recessive predisposition 4 | 1,442
Dehydration 4 | 40
Failure to gain weight 4 | 365
Feeding difficulties in infancy 4 | 175
Hyperaldosteronism 4 | 35
Hyperkalemia 4 | 17
Hypertensive disease 4 | 292
Hyponatremia 4 | 25
Hypotension 4 | 82
Pediatric failure to thrive 4 | 365
Renal salt wasting 4 | 18
Vomiting 4 | 116
lung cancer 4 | 4,740
osteosarcoma 4 | 7,950
Bronchiectasis 3 | 64
Bronchitis, Chronic 3 | 12
Diarrhea 3 | 253
Edema 3 | 81
Hyperactive renin-angiotensin system 3 | 8
Hypertensive disorder 3 | 56
Hypoaldosteronism 3 | 12
Hypokalemia 3 | 52
Hypokalemia Prevention 3 | 6
Idiopathic bronchiectasis 3 | 4
Increase in blood pressure 3 | 119
Increased plasma renin activity 3 | 8
Infantile onset 3 | 238
Liddle syndrome 3 | 14
Metabolic acidosis 3 | 90
Mineralocorticoid insufficiency 3 | 12
Peripheral Edema due to Chronic Heart Failure 3 | 10
Pseudohypoaldosteronism 3 | 23
Pseudohypoaldosteronism, Type I, Autosomal Recessive 3 | 3
Pulmonary Edema due to Chronic Heart Failure 3 | 6
Recurrent respiratory infections 3 | 141
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
atypical teratoid / rhabdoid tumor 3 | 5,112
autosomal recessive pseudohypoaldosteronism type 1 3 | 3
cystic fibrosis 3 | 1,696
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
psoriasis 3 | 6,694
Amyotrophic lateral sclerosis 2 | 451
Brain Ischemia 2 | 110
Breast cancer 2 | 3,578
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Cerebral Ischemia 2 | 37
Conduction disorder of the heart 2 | 79
Congenital adrenal hyperplasia 2 | 73
Constipation 2 | 181
Decreased plasma renin activity 2 | 9
Dyschezia 2 | 135
EKG abnormalities 2 | 78
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Fatigue 2 | 182
Hypokalemic alkalosis 2 | 4
Kidney Diseases 2 | 114
Kidney Failure 2 | 111
Kidney cancer 2 | 2,613
Kidney damage 2 | 25
Lung diseases 2 | 50
Muscle Weakness 2 | 170
Obesity 2 | 678
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Tinea corporis 2 | 25
Tinea pedis 2 | 29
active Crohn's disease 2 | 922
adult high grade glioma 2 | 3,801
cutaneous lupus erythematosus 2 | 1,057
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
ulcerative colitis 2 | 1,819
Chromosome 17q12 deletion syndrome 1 | 16
Diagnostic Test for Secondary Adrenocortical Insufficiency 1 | 4
Erythropoietic protoporphyria 1 | 15
Exacerbation of multiple sclerosis 1 | 2
Fuhrmann syndrome 1 | 7
Neoplasms, Germ Cell and Embryonal 1 | 15
Neurogenic bladder 1 | 16
Seborrheic dermatitis 1 | 31
Stevens-Johnson syndrome 1 | 92
Urethral diverticulum 1 | 3

Tissue

Endocrine System 11 | 18,159
Digestive Tract 9 | 17,369
Female tissues 9 | 17,400
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Blood and immune system 8 | 16,909
Liver and Pancreas 8 | 16,750
Respiratory system 8 | 16,393
Cardiovascular System 6 | 15,192

Target Family

Ion Channel 4 | 344
Non-IDG 4 | 12,091
Enzyme 1 | 4,145
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Process

sodium ion homeostasis 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Melanocortin receptor 3 MC3R Tchem GPCR -2.65556 445.3 202
Cytochrome P450 4A11 CYP4A11 Tbio Non-IDG -1.97180 93.7 142
Cytochrome P450 11B2, mitochondrial CYP11B2 Tchem Non-IDG -2.82678 695.9 162
Uroplakin-3a UPK3A Tbio Non-IDG -1.93837 84.0 144
Phylloquinone omega-hydroxylase CYP4F2 CYP4F2 Tchem Enzyme -2.16137 145.5 83
Amiloride-sensitive sodium channel subunit alpha SCNN1A Tclin Ion Channel -1.84273 63.2 184
Cytochrome P450 4F12 CYP4F12 Tdark Non-IDG -0.88794 8.48 0
Amiloride-sensitive sodium channel subunit beta SCNN1B Tclin Ion Channel -1.75374 52.6 316
Amiloride-sensitive sodium channel subunit gamma SCNN1G Tclin Ion Channel -2.10269 131.1 212
Sodium channel protein type 7 subunit alpha SCN7A Tclin Ion Channel -0.99420 8.52 83