Development Level

Tbio 38 | 11,445
Tclin 8 | 613
Tchem 6 | 1,598
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal locomotor behavior 3 | 24
decreased circulating HDL chol... 3 | 68
decreased fasted circulating g... 3 | 65
decreased grip strength 3 | 116
decreased total body fat amoun... 3 | 207
increased circulating chloride... 3 | 41
increased lean body mass 3 | 172
preweaning lethality, complete... 3 | 979
tremors 3 | 39
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
decreased bone mineral content 2 | 151
decreased circulating LDL chol... 2 | 38
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased pulmonary respirator... 2 | 5
enlarged stomach 2 | 2
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased red blood cell distr... 2 | 34
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
small thymus 2 | 16
abnormal behavioral response t... 1 | 66
abnormal epididymis morphology 1 | 42
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating calcium ... 1 | 36
decreased exploration in new e... 1 | 11
decreased large unstained cell... 1 | 11
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased aggression 1 | 4
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101

Disease

Carcinoma 43 | 11,493
medulloblastoma, large-cell 35 | 6,241
Schizophrenia 31 | 1,160
ependymoma 28 | 4,679
Autistic Disorder 27 | 364
atypical teratoid / rhabdoid tumor 27 | 5,112
adult high grade glioma 24 | 3,801
psoriasis 24 | 6,694
glioblastoma 23 | 5,792
Intellectual disability 22 | 1,016
osteosarcoma 22 | 7,950
Astrocytoma, Pilocytic 20 | 3,081
ovarian cancer 19 | 8,520
Breast cancer 18 | 3,578
Kidney cancer 18 | 2,613
group 3 medulloblastoma 17 | 4,104
primitive neuroectodermal tumor 17 | 3,035
Bipolar Disorder 16 | 666
oligodendroglioma 16 | 2,850
Autism spectrum disorder 15 | 101
subependymal giant cell astrocytoma 15 | 2,287
lung carcinoma 14 | 2,843
Depressive disorder 13 | 409
Major Depressive Disorder 13 | 301
Unipolar Depression 13 | 250
Epilepsy 12 | 792
Mental Depression 12 | 333
invasive ductal carcinoma 12 | 2,951
Liver cancer 11 | 604
Obesity 11 | 678
Pick disease 11 | 1,894
Alcoholic Intoxication, Chronic 10 | 289
Autism Spectrum Disorders 10 | 75
Parkinson's disease 10 | 392
astrocytic glioma 10 | 2,597
lung cancer 10 | 4,740
malignant mesothelioma 10 | 3,232
Asperger syndrome 9 | 37
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Mood Disorders 9 | 184
Poor school performance 9 | 645
Seizures 9 | 596
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Autosomal recessive predisposition 8 | 1,442
Melanoma 8 | 711
diabetes mellitus 8 | 1,728
group 4 medulloblastoma 8 | 1,855
pancreatic cancer 8 | 2,398
Alzheimer's disease 7 | 658
Attention deficit hyperactivity disorder 7 | 278
Cancer 7 | 2,499
Cerebellar Ataxia 7 | 304
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Hypertension 7 | 396
Hypertensive disease 7 | 292
Mental and motor retardation 7 | 608
Nicotine dependence 7 | 54
Psychotic Disorders 7 | 151
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung adenocarcinoma 7 | 2,716
pituitary cancer 7 | 1,972
Amyotrophic lateral sclerosis 6 | 451
Anxiety Disorders 6 | 38
Delayed speech and language development 6 | 112
Endometrial cancer 6 | 311
Gilles de la Tourette syndrome 6 | 47
Language Delay 6 | 112
Muscle hypotonia 6 | 571
Skin cancer 6 | 469
Speech Delay 6 | 112
Speech impairment 6 | 112
Vascular disease 6 | 319
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
colon cancer 6 | 1,478
ductal carcinoma in situ 6 | 1,745
non-small cell lung cancer 6 | 2,890
Acquired scoliosis 5 | 281
Cocaine-Related Disorders 5 | 92
Curvature of spine 5 | 282
Long philtrum 5 | 137
Opiate dependence 5 | 29
Short stature 5 | 531
Toxic encephalopathy 5 | 141
cystic fibrosis 5 | 1,696
nasopharyngeal carcinoma 5 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Asthma 4 | 385
Hypoplastic mandible condyle 4 | 275
Rheumatoid arthritis 4 | 1,191
Strabismus 4 | 270
chronic rhinosinusitis 4 | 512
interstitial cystitis 4 | 2,312
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720

Tissue

Endocrine System 51 | 18,159
Skin and soft tissues 49 | 17,230
Female tissues 48 | 17,400
Blood and immune system 47 | 16,909
Digestive Tract 47 | 17,369
Nervous System 47 | 16,725
Liver and Pancreas 46 | 16,750
Urinary Tract 46 | 16,678
Male tissues 45 | 17,142
Respiratory system 41 | 16,393
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 29 | 12,091
Enzyme 8 | 4,145
GPCR 5 | 408
Transcription Factor 5 | 1,400
Ion Channel 3 | 344
Kinase 2 | 634
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

social behavior 54 | 54
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Protein capicua homolog CIC Tbio Transcription Factor -1.88267 74.4 156
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
Vacuolar protein sorting-associated protein 13A VPS13A Tbio Non-IDG -2.19966 172.3 22
Neurexin-3 NRXN3 Tbio Non-IDG -1.34072 34.8 172
Contactin-associated protein-like 2 CNTNAP2 Tbio Non-IDG -2.36156 228.4 191
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
Neuronal acetylcholine receptor subunit beta-2 CHRNB2 Tclin Ion Channel -1.62448 37.6 174
Patched domain-containing protein 1 PTCHD1 Tbio Non-IDG -0.84569 7.72 81