Development Level

Tbio 49 | 10,625
Tdark 14 | 7,003
Tchem 7 | 1,890

IMPC Term

preweaning lethality, complete... 9 | 633
embryonic lethality prior to o... 3 | 148
embryonic lethality prior to t... 3 | 187
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal foot plate morphology 1 | 2
abnormal heart morphology 1 | 51
abnormal humerus morphology 1 | 11
abnormal lens morphology 1 | 73
abnormal retina morphology 1 | 100
abnormal skin morphology 1 | 23
cataract 1 | 26
craniofacial phenotype 1 | 9
decreased CD103-positive CD11b... 1 | 2
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating amylase ... 1 | 24
decreased circulating sodium l... 1 | 18
decreased eosinophil cell numb... 1 | 41
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
enlarged epididymis 1 | 27
enlarged heart 1 | 111
hydrops fetalis 1 | 22
hypoactivity 1 | 89
increased circulating free fat... 1 | 17
increased circulating magnesiu... 1 | 10
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased mean corpuscular hem... 1 | 25
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
preweaning lethality, incomple... 1 | 260
vertebral transformation 1 | 12

Disease

ovarian cancer 41 | 8,484
osteosarcoma 30 | 7,933
psoriasis 19 | 6,685
lung cancer 18 | 4,466
malignant mesothelioma 16 | 3,162
glioblastoma 13 | 5,572
group 3 medulloblastoma 13 | 2,254
medulloblastoma, large-cell 13 | 6,234
atypical teratoid / rhabdoid tumor 11 | 4,369
Multiple myeloma 10 | 1,327
Breast cancer 9 | 3,094
oligodendroglioma 8 | 2,849
Pick disease 7 | 1,893
acute myeloid leukemia 7 | 780
acute quadriplegic myopathy 7 | 1,157
astrocytic glioma 7 | 2,241
ependymoma 7 | 2,514
hepatocellular carcinoma 7 | 532
non-small cell lung cancer 7 | 2,798
Cancer 6 | 2,346
astrocytoma 6 | 1,493
diabetes mellitus 6 | 1,663
pediatric high grade glioma 6 | 2,712
primitive neuroectodermal tumor 6 | 3,031
Carcinoma 5 | 2,147
Cockayne syndrome 5 | 54
cystic fibrosis 5 | 1,665
invasive ductal carcinoma 5 | 2,950
medulloblastoma 5 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
pituitary cancer 5 | 1,972
Photosensitive trichothiodystrophy 4 | 24
breast carcinoma 4 | 1,614
dermatomyositis 4 | 933
non primary Sjogren syndrome sicca 4 | 840
pancreatic cancer 4 | 2,300
primary pancreatic ductal adenocarcinoma 4 | 1,271
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 2,087
group 4 medulloblastoma 3 | 1,875
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
juvenile dermatomyositis 3 | 1,189
lung adenocarcinoma 3 | 2,713
pancreatic carcinoma 3 | 567
posterior fossa group A ependymoma 3 | 1,511
sonic hedgehog group medulloblastoma 3 | 1,482
tuberculosis and treatment for 3 months 3 | 327
tuberculosis and treatment for 6 months 3 | 686
Acquired immunodeficiency syndrome 2 | 164
Epidermodysplasia verruciformis 2 | 21
IGA Glomerulonephritis 2 | 454
Mixed connective tissue disease 2 | 16
Peripheral Neuropathy 2 | 303
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 918
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 430
inflammatory breast cancer 2 | 404
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
lung carcinoma 2 | 2,844
nasopharyngeal carcinoma 2 | 1,056
pilocytic astrocytoma 2 | 3,086
primary Sjogren syndrome 2 | 789
tuberculosis 2 | 1,557
Ankylosing spondylitis 1 | 138
Atrial Fibrillation 1 | 110
Bipolar Disorder 1 | 266
Cardiovascular system disease 1 | 194
Choreatic disease 1 | 27
Chronic obstructive pulmonary disease 1 | 146
Cocaine-Related Disorders 1 | 88
Dementia 1 | 129
Dystonia 1 | 77
Eumycotic mycetoma 1 | 3
Fusariosis 1 | 6
Gaucher disease type 1 1 | 171
Gaucher disease type 3 1 | 76
HIV Infections 1 | 100
Huntington's disease 1 | 72
Leukemia 1 | 88
Lymphoma 1 | 56
Machado-Joseph disease 1 | 18
Malignant neoplasm of breast 1 | 63
Megaloblastic anemia 1 | 16
Muscular atrophy 1 | 67
Neoplasm Metastasis 1 | 138
Neurodegenerative disease 1 | 383
Osteoporosis 1 | 257
Poland syndrome 1 | 7
Subcutaneous mycosis 1 | 1
Thalassemia 1 | 46
Tinea pedis 1 | 30
Vasculitis 1 | 64
active ulcerative colitis 1 | 477
dentatorubral-pallidoluysian atrophy 1 | 21
hereditary spastic paraplegia 1 | 313
interstitial lung disease 1 | 291
sarcoidosis 1 | 358
type II diabetes mellitus and post-ischemic heart failure 1 | 89

Tissue

Blood and immune system 70 | 17,995
Cardiovascular System 70 | 17,958
Digestive Tract 70 | 18,473
Endocrine System 70 | 18,512
Female tissues 70 | 18,647
Liver and Pancreas 70 | 18,136
Male tissues 70 | 17,969
Nervous System 70 | 18,561
Respiratory system 69 | 17,484
Skin and soft tissues 69 | 18,115
Urinary Tract 69 | 18,444

Target Family

Non-IDG 46 | 11,971
Enzyme 16 | 4,146
Transcription Factor 5 | 1,400
Kinase 2 | 634
Epigenetic 1 | 242

GO Process

snRNA transcription from RNA p... 70 | 70
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA-directed RNA polymerase II subunit RPB7 POLR2G Tbio Enzyme -1.74939 59.4 153
General transcription factor IIF subunit 2 GTF2F2 Tbio Non-IDG -1.54703 35.9 153
Integrator complex subunit 5 INTS5 Tdark Non-IDG -1.17506 15.4 45
POU domain, class 2, transcription factor 2 POU2F2 Tchem Transcription Factor -1.45774 28.7 332
Cyclin-dependent kinase 7 CDK7 Tchem Kinase -2.28652 191.1 505
Transcription initiation factor TFIID subunit 6 TAF6 Tbio Non-IDG -1.10513 12.5 129
DNA-directed RNA polymerase II subunit RPB4 POLR2D Tdark Enzyme -0.50937 3.13 114
General transcription factor IIF subunit 1 GTF2F1 Tbio Non-IDG -1.59692 42.8 148
Integrator complex subunit 2 INTS2 Tdark Non-IDG -0.02119 1.05 38
DNA-directed RNA polymerases I, II, and III subunit RPABC5 POLR2L Tbio Enzyme -0.98287 10.2 60