Development Level

Tbio 55 | 11,651
Tdark 11 | 6,593
Tchem 4 | 1,388

IMPC Phenotype

preweaning lethality, complete... 14 | 979
embryonic lethality prior to o... 7 | 239
embryonic lethality prior to t... 6 | 278
abnormal embryo size 3 | 220
abnormal heart morphology 2 | 162
increased circulating potassiu... 2 | 29
abnormal chorioallantoic fusio... 1 | 8
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart 1 | 210
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating magnesiu... 1 | 10
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74

Disease

Carcinoma 42 | 11,493
ovarian cancer 41 | 8,520
osteosarcoma 30 | 7,950
lung cancer 19 | 4,740
psoriasis 19 | 6,694
group 3 medulloblastoma 16 | 4,104
malignant mesothelioma 16 | 3,232
glioblastoma 13 | 5,792
medulloblastoma, large-cell 13 | 6,241
Breast cancer 11 | 3,578
Kidney cancer 11 | 2,613
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
Multiple myeloma 10 | 1,332
oligodendroglioma 8 | 2,850
Pick disease 7 | 1,894
acute myeloid leukemia 7 | 783
acute quadriplegic myopathy 7 | 1,158
astrocytic glioma 7 | 2,597
hepatocellular carcinoma 7 | 547
non-small cell lung cancer 7 | 2,890
Cancer 6 | 2,499
astrocytoma 6 | 1,146
diabetes mellitus 6 | 1,728
group 4 medulloblastoma 6 | 1,855
primitive neuroectodermal tumor 6 | 3,035
Cockayne syndrome 5 | 60
adult high grade glioma 5 | 3,801
cystic fibrosis 5 | 1,696
invasive ductal carcinoma 5 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Hereditary spherocytosis type 5 4 | 12
Photosensitive trichothiodystrophy 4 | 30
Xeroderma pigmentosum group B 4 | 20
breast carcinoma 4 | 1,638
dermatomyositis 4 | 966
non primary Sjogren syndrome sicca 4 | 891
pancreatic cancer 4 | 2,398
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
pancreatic carcinoma 3 | 562
tuberculosis and treatment for 3 months 3 | 179
Acquired immunodeficiency syndrome 2 | 197
Astrocytoma, Pilocytic 2 | 3,081
Bipolar Disorder 2 | 666
Congenital myasthenic syndrome 5 2 | 11
Epidermodysplasia verruciformis 2 | 21
Intellectual disability 2 | 1,016
Mixed connective tissue disease 2 | 16
Paranoia 2 | 20
Periventricular nodular heterotopia 2 | 30
Schizophrenia 2 | 1,160
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 459
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
Acute Promyelocytic Leukemia 1 | 40
Alagille syndrome 1 | 15
Ankylosing spondylitis 1 | 140
Autosomal dominant cerebellar ataxia 1 | 33
Brain disease 1 | 96
Broad-based gait 1 | 19
COPD 1 | 118
Chronic schizophrenia 1 | 16
Deglutition Disorders 1 | 132
Diffuse cerebral atrophy 1 | 8
Facioscapulohumeral muscular dystrophy 1 | 26
Gaucher disease type 3 1 | 67
Granulosa cell tumor 1 | 6
Hallucinations 1 | 34
Hallucinations, Sensory 1 | 33
Hereditary spherocytosis type 2 1 | 18
Lymphoid leukemia 1 | 160
Muscle Rigidity 1 | 49
Muscular atrophy 1 | 71
Myoclonus 1 | 74
Nonorganic psychosis 1 | 84
PARKINSON DISEASE, LATE-ONSET 1 | 20
Panic disorder 1 | 61
Parkinsonian Disorders 1 | 56
Prader-Willi syndrome 1 | 48
Roberts syndrome 1 | 15
Romberg's sign positive 1 | 4
Specific language impairment 1 | 34
Thalassemia 1 | 53
chorea-acanthocytosis 1 | 12
interstitial lung disease 1 | 298

Tissue

Blood and immune system 70 | 16,909
Cardiovascular System 70 | 15,192
Digestive Tract 70 | 17,369
Endocrine System 70 | 18,159
Female tissues 70 | 17,400
Liver and Pancreas 70 | 16,750
Male tissues 70 | 17,142
Nervous System 70 | 16,725
Respiratory system 70 | 16,393
Skin and soft tissues 70 | 17,230
Urinary Tract 70 | 16,678

Target Family

Non-IDG 46 | 12,091
Enzyme 16 | 4,145
Transcription Factor 5 | 1,400
Kinase 2 | 634
Epigenetic 1 | 242

GO Process

snRNA transcription from RNA p... 70 | 70
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
snRNA-activating protein complex subunit 4 SNAPC4 Tbio Transcription Factor -0.99715 10.0 160
Integrator complex subunit 6 INTS6 Tbio Non-IDG -2.07240 118.9 80
Transcription initiation factor IIB GTF2B Tbio Non-IDG -2.63302 410.1 286
Nuclear cap-binding protein subunit 2 NCBP2 Tbio Non-IDG -1.45099 24.2 110
Integrator complex subunit 10 INTS10 Tdark Non-IDG -0.67290 3.96 116
DNA-directed RNA polymerase II subunit RPB11-a POLR2J Tbio Enzyme -1.43224 29.3 213
Nuclear cap-binding protein subunit 1 NCBP1 Tbio Non-IDG -2.34134 207.7 172
DNA-directed RNA polymerase II subunit RPB7 POLR2G Tbio Enzyme -1.77350 60.4 174
Zinc finger protein 143 ZNF143 Tbio Transcription Factor -2.48767 308.2 62
Transcription initiation factor IIA subunit 2 GTF2A2 Tbio Non-IDG -1.18688 16.5 42