Development Level

Tbio 46 | 11,445
Tchem 10 | 1,598
Tdark 7 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 3 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
increased body weight 2 | 25
increased total body fat amoun... 2 | 134
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal locomotor behavior 1 | 24
abnormal pericardium morpholog... 1 | 26
abnormal response to tactile s... 1 | 17
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal vocalization 1 | 21
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating total pr... 1 | 49
decreased heart left ventricle... 1 | 28
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
hydroencephaly 1 | 14
hyperactivity 1 | 148
increased aggression 1 | 4
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased circulating triglyce... 1 | 42
increased heart rate variabili... 1 | 7
increased kidney weight 1 | 6
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
limb grasping 1 | 41
male infertility 1 | 123
small adrenal glands 1 | 16
small kidney 1 | 16
thin ventricular wall 1 | 24

Disease

Carcinoma 49 | 11,493
osteosarcoma 34 | 7,950
ependymoma 33 | 4,679
ovarian cancer 33 | 8,520
glioblastoma 25 | 5,792
psoriasis 25 | 6,694
atypical teratoid / rhabdoid tumor 24 | 5,112
lung cancer 23 | 4,740
Gastrointestinal Stromal Tumors 22 | 48
Polydactyly 21 | 107
medulloblastoma, large-cell 20 | 6,241
group 3 medulloblastoma 19 | 4,104
Intellectual disability 17 | 1,016
Kidney cancer 17 | 2,613
malignant mesothelioma 17 | 3,232
Autosomal recessive predisposition 16 | 1,442
oligodendroglioma 15 | 2,850
Dull intelligence 14 | 645
Joubert syndrome 14 | 66
Low intelligence 14 | 645
Mental Retardation 14 | 645
Mental deficiency 14 | 645
Poor school performance 14 | 645
Breast cancer 13 | 3,578
Short stature 13 | 531
adult high grade glioma 13 | 3,801
Cancer 12 | 2,499
Cognitive delay 12 | 608
Global developmental delay 12 | 608
Mental and motor retardation 12 | 608
Astrocytoma, Pilocytic 11 | 3,081
Holoprosencephaly 11 | 56
Nephronophthisis 11 | 80
astrocytic glioma 11 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
lung adenocarcinoma 11 | 2,716
Asphyxiating thoracic dystrophy 10 | 44
invasive ductal carcinoma 10 | 2,951
lung carcinoma 10 | 2,843
pancreatic cancer 10 | 2,398
Brachydactyly 9 | 156
Congenital hypoplasia of penis 9 | 176
Hypoplastic mandible condyle 9 | 275
Mandibular hypoplasia 9 | 275
Micrognathism 9 | 275
Orbital separation excessive 9 | 244
Pick disease 9 | 1,894
Ulnar polydactyly of fingers 9 | 47
cystic fibrosis 9 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
primitive neuroectodermal tumor 9 | 3,035
subependymal giant cell astrocytoma 9 | 2,287
Abnormally small eyeball 8 | 97
Ciliopathy 8 | 71
Cleft Palate 8 | 271
Cryptorchidism 8 | 296
Decreased size of eyeball 8 | 97
Meckel syndrome 8 | 46
Microphthalmos 8 | 100
Rheumatoid arthritis 8 | 1,191
Small head 8 | 374
pediatric high grade glioma 8 | 1,064
Bardet-Biedl syndrome 7 | 51
Cleft Lip 7 | 141
Epilepsy 7 | 792
Lobar Holoprosencephaly 7 | 20
Nystagmus 7 | 317
Seizures 7 | 596
non-small cell lung cancer 7 | 2,890
Cataract 6 | 297
Congenital Epicanthus 6 | 177
Hypertensive disease 6 | 292
Hypogonadism 6 | 173
Hypotrophic malar bone 6 | 129
Increase in blood pressure 6 | 119
Lens Opacities 6 | 231
Malar flattening 6 | 129
Muscle hypotonia 6 | 571
Nevoid basal cell carcinoma syndrome 6 | 16
Obesity 6 | 678
Orbital separation diminished 6 | 23
Syndactyly of the toes 6 | 45
active Crohn's disease 6 | 922
adrenocortical carcinoma 6 | 1,428
chronic rhinosinusitis 6 | 512
diabetes mellitus 6 | 1,728
interstitial cystitis 6 | 2,312
medulloblastoma 6 | 720
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primary pancreatic ductal adenocarcinoma 6 | 1,109
progressive supranuclear palsy 6 | 676
Agenesis of corpus callosum 5 | 83
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Meckel-Gruber syndrome 5 | 13
Multicystic Dysplastic Kidney 5 | 52
Retinitis Pigmentosa 5 | 226
Uranostaphyloschisis 5 | 167
ductal carcinoma in situ 5 | 1,745

Tissue

Digestive Tract 64 | 17,369
Endocrine System 64 | 18,159
Liver and Pancreas 63 | 16,750
Nervous System 63 | 16,725
Female tissues 62 | 17,400
Male tissues 62 | 17,142
Skin and soft tissues 61 | 17,230
Urinary Tract 61 | 16,678
Respiratory system 60 | 16,393
Blood and immune system 59 | 16,909
Cardiovascular System 52 | 15,192

Target Family

Non-IDG 39 | 12,091
Transcription Factor 10 | 1,400
Kinase 7 | 634
Enzyme 6 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

smoothened signaling pathway 64 | 64
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Transmembrane protein 17 TMEM17 Tbio Non-IDG 0.61 0.56 52
Intraflagellar transport protein 25 homolog HSPB11 Tbio Non-IDG -1.40552 26.1 61
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Mitogen-activated protein kinase kinase kinase 10 MAP3K10 Tchem Kinase -1.20048 15.1 221
WD repeat-containing and planar cell polarity effector protein fritz homolog WDPCP Tbio Non-IDG -0.84019 7.08 68
Patched domain-containing protein 1 PTCHD1 Tbio Non-IDG -0.84569 7.72 81
Intraflagellar transport protein 52 homolog IFT52 Tbio Non-IDG -1.09507 12.7 13
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
B9 domain-containing protein 1 B9D1 Tdark Non-IDG -0.61316 3.72 43