Development Level

Tbio 10 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
enlarged heart 1 | 210
enlarged spleen 1 | 41
hydrometra 1 | 53
hypoactivity 1 | 132
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
scaly skin 1 | 4
small superior vagus ganglion 1 | 74

Disease

Carcinoma 10 | 11,493
osteosarcoma 10 | 7,950
ovarian cancer 9 | 8,520
psoriasis 8 | 6,694
lung cancer 7 | 4,740
non-small cell lung cancer 6 | 2,890
Cancer 5 | 2,499
glioblastoma 5 | 5,792
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
Short stature 4 | 531
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
spina bifida 4 | 1,074
Blepharoptosis 3 | 231
Cleft Palate 3 | 271
Congenital Epicanthus 3 | 177
Craniofacial Abnormalities 3 | 151
Cryptorchidism 3 | 296
Hypotrophic malar bone 3 | 129
Kidney cancer 3 | 2,613
Malar flattening 3 | 129
Orbital separation excessive 3 | 244
Osteoarthritis 3 | 184
Ovarian Neoplasms 3 | 102
Schizophrenia 3 | 1,160
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
oligodendroglioma 3 | 2,850
ovarian neoplasm 3 | 99
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
urothelial carcinoma 3 | 318
Absent auditory canals 2 | 23
Absent external auditory canals 2 | 23
Acquired scoliosis 2 | 281
Atresia of the external auditory canal 2 | 23
Atretic auditory canal 2 | 23
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Brachydactyly 2 | 156
Cleft palate with cleft lip 2 | 23
Cognitive delay 2 | 608
Colorectal Neoplasms 2 | 243
Concave bridge of nose 2 | 195
Curvature of spine 2 | 282
Decreased projection of midface 2 | 105
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Down syndrome 2 | 499
Downward slant of palpebral fissure 2 | 158
Exophthalmos 2 | 112
Freckles 2 | 33
High forehead 2 | 102
Hypertension 2 | 396
Hypoplastic mandible condyle 2 | 275
Hypotrophic midface 2 | 105
Liver cancer 2 | 604
Lymphoid leukemia 2 | 160
Melanocytic nevus 2 | 43
Melanoma 2 | 711
Mental and motor retardation 2 | 608
Midface retrusion 2 | 105
Multiple myeloma 2 | 1,332
Oral cleft 2 | 18
Pick disease 2 | 1,894
Posteriorly rotated ear 2 | 61
Proteinuria 2 | 144
RENAL ADYSPLASIA 2 | 25
Renal dysplasia 2 | 28
Rheumatoid arthritis 2 | 1,191
Skin cancer 2 | 469
Small midface 2 | 105
Syndactyly of the toes 2 | 45
Tall forehead 2 | 102
Tooth agenesis 2 | 44
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
cystic fibrosis and chronic rhinosinusitis 2 | 214
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 4,104
interstitial lung disease 2 | 298
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192

Target Family

Non-IDG 8 | 12,091
Transcription Factor 3 | 1,400
Enzyme 1 | 4,145

GO Process

smooth muscle tissue developme... 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Receptor for retinol uptake STRA6 STRA6 Tbio Non-IDG -1.78205 67.9 157
Zinc finger protein 84 ZNF84 Tdark Transcription Factor -0.57958 3.24 27
Integrin alpha-8 ITGA8 Tbio Non-IDG -1.36974 22.0 145
Neurofibromin NF1 Tbio Non-IDG -3.60161 4054.2 355
Indian hedgehog protein IHH Tbio Non-IDG -2.61880 417.4 375
AN1-type zinc finger protein 5 ZFAND5 Tbio Non-IDG -0.66552 5.05 159
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.21660 1658.5 540
Disks large homolog 1 DLG1 Tbio Non-IDG -2.19822 171.8 185
Tumor protein 63 TP63 Tbio Transcription Factor -3.07398 1154.1 448