Development Level

Tbio 88 | 11,445
Tdark 21 | 6,588
Tchem 10 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
enlarged heart 3 | 210
cataract 2 | 92
decreased blood urea nitrogen ... 2 | 51
decreased bone mineral content 2 | 151
decreased lean body mass 2 | 135
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased blood urea nitrogen ... 2 | 48
abnormal allantois morphology 1 | 8
abnormal blood vessel morpholo... 1 | 5
abnormal brain morphology 1 | 13
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal heart looping 1 | 5
abnormal hindbrain development 1 | 16
abnormal left-right axis patte... 1 | 2
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
decreased IgG1 level 1 | 8
decreased IgG2b level 1 | 4
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased granulocyte number 1 | 6
decreased heart left ventricle... 1 | 28
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
hydroencephaly 1 | 14
impaired pupillary reflex 1 | 26
increased body length 1 | 32
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating potassiu... 1 | 29
increased heart rate 1 | 23
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
polycystic kidney 1 | 15
prolonged PQ interval 1 | 5
prolonged PR interval 1 | 15
short tibia 1 | 97
shortened RR interval 1 | 17
shortened ST segment 1 | 10
thin ventricular wall 1 | 24

Disease

Carcinoma 67 | 11,493
osteosarcoma 63 | 7,950
glioblastoma 59 | 5,792
ovarian cancer 59 | 8,520
medulloblastoma, large-cell 53 | 6,241
atypical teratoid / rhabdoid tumor 47 | 5,112
ependymoma 42 | 4,679
psoriasis 42 | 6,694
adult high grade glioma 41 | 3,801
lung cancer 40 | 4,740
primitive neuroectodermal tumor 38 | 3,035
Astrocytoma, Pilocytic 37 | 3,081
group 3 medulloblastoma 37 | 4,104
Breast cancer 34 | 3,578
oligodendroglioma 32 | 2,850
lung carcinoma 31 | 2,843
invasive ductal carcinoma 30 | 2,951
non-small cell lung cancer 29 | 2,890
astrocytic glioma 28 | 2,597
interstitial cystitis 28 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
malignant mesothelioma 27 | 3,232
subependymal giant cell astrocytoma 27 | 2,287
Kidney cancer 24 | 2,613
group 4 medulloblastoma 22 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
Pick disease 21 | 1,894
pancreatic cancer 21 | 2,398
spina bifida 20 | 1,074
ulcerative colitis 20 | 1,819
lung adenocarcinoma 19 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
Cancer 17 | 2,499
ductal carcinoma in situ 17 | 1,745
tuberculosis 17 | 2,010
pituitary cancer 16 | 1,972
astrocytoma 13 | 1,146
breast carcinoma 13 | 1,638
cystic fibrosis 13 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
acute quadriplegic myopathy 12 | 1,158
cutaneous lupus erythematosus 12 | 1,057
juvenile dermatomyositis 12 | 1,187
Multiple myeloma 11 | 1,332
diabetes mellitus 10 | 1,728
Liver Cirrhosis, Experimental 9 | 769
dermatomyositis 9 | 966
progressive supranuclear palsy 9 | 676
Chronic Lymphocytic Leukemia 8 | 262
Rheumatoid arthritis 8 | 1,191
Schizophrenia 8 | 1,160
active Crohn's disease 8 | 922
esophageal adenocarcinoma 8 | 737
nasopharyngeal carcinoma 8 | 1,058
primary pancreatic ductal adenocarcinoma 8 | 1,109
Waldenstrons macroglobulinemia 7 | 765
colon cancer 7 | 1,478
pediatric high grade glioma 7 | 1,064
Alzheimer's disease 6 | 658
Liver cancer 6 | 604
Melanoma 6 | 711
gastric carcinoma 6 | 807
hereditary spastic paraplegia 6 | 318
medulloblastoma 6 | 720
non primary Sjogren syndrome sicca 6 | 891
primary Sjogren syndrome 6 | 735
sarcoidosis 6 | 370
Duchenne muscular dystrophy 5 | 601
Intellectual disability 5 | 1,016
adrenocortical carcinoma 5 | 1,428
gastric cancer 5 | 459
mucosa-associated lymphoid tissue lymphoma 5 | 484
urothelial carcinoma 5 | 318
Atopic dermatitis 4 | 952
Autosomal recessive predisposition 4 | 1,442
Breast Neoplasms 4 | 445
Cardiomegaly 4 | 116
Joubert syndrome 4 | 66
Multiple Sclerosis 4 | 540
Parkinson's disease 4 | 392
Prostatic Neoplasms 4 | 495
Vascular disease 4 | 319
active ulcerative colitis 4 | 764
acute myeloid leukemia 4 | 783
aldosterone-producing adenoma 4 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
glioblastoma multiforme 4 | 142
posterior fossa group A ependymoma 4 | 468
Bipolar Disorder 3 | 666
Curvature of spine 3 | 282
Down syndrome 3 | 499
Epilepsy 3 | 792
Hypertensive disease 3 | 292
Muscle hypotonia 3 | 571
Myocardial Ischemia 3 | 169
Retinitis Pigmentosa 3 | 226
Short stature 3 | 531
fibroadenoma 3 | 559
pancreatic carcinoma 3 | 562
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 119 | 18,159
Digestive Tract 118 | 17,369
Female tissues 118 | 17,400
Male tissues 118 | 17,142
Blood and immune system 117 | 16,909
Liver and Pancreas 117 | 16,750
Skin and soft tissues 117 | 17,230
Urinary Tract 117 | 16,678
Nervous System 115 | 16,725
Respiratory system 115 | 16,393
Cardiovascular System 111 | 15,192

Target Family

Enzyme 61 | 4,145
Non-IDG 57 | 12,091
Kinase 1 | 634

GO Process

small GTPase mediated signal t... 119 | 119
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ADP-ribosylation factor-like protein 5A ARL5A Tbio Enzyme -1.27307 18.8 53
ADP-ribosylation factor-related protein 1 ARFRP1 Tbio Enzyme -1.22088 20.8 63
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Rap guanine nucleotide exchange factor 2 RAPGEF2 Tbio Non-IDG -1.41107 29.0 79
Putative ADP-ribosylation factor-like protein 5C ARL5C Tdark Enzyme 0.00000 1.00 39
SH2 domain-containing protein 3A SH2D3A Tbio Non-IDG -2.47559 291.4 103
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.63966 41.9 162
ADP-ribosylation factor-like protein 8B ARL8B Tbio Enzyme -0.99083 12.0 99
Ras-GEF domain-containing family member 1A RASGEF1A Tdark Non-IDG -0.56596 3.21 50
Rab proteins geranylgeranyltransferase component A 2 CHML Tbio Enzyme -1.90137 73.3 126