Development Level

Tbio 155 | 10,625
Tdark 42 | 7,003
Tchem 18 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
decreased lean body mass 6 | 195
decreased bone mineral content 5 | 157
enlarged heart 5 | 111
preweaning lethality, incomple... 5 | 260
abnormal behavior 4 | 226
abnormal embryo size 3 | 112
abnormal heart morphology 3 | 51
abnormal retina morphology 3 | 100
abnormal retinal pigmentation 3 | 61
decreased body weight 3 | 174
embryonic lethality prior to t... 3 | 187
increased circulating alkaline... 3 | 119
abnormal cranium morphology 2 | 32
abnormal gait 2 | 51
abnormal head morphology 2 | 10
abnormal joint morphology 2 | 14
abnormal limb bud morphology 2 | 15
abnormal neural tube closure 2 | 37
abnormal rib morphology 2 | 28
abnormal snout morphology 2 | 18
abnormal tooth morphology 2 | 24
corneal opacity 2 | 25
decreased blood urea nitrogen ... 2 | 31
decreased body length 2 | 108
decreased bone mineral density 2 | 126
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular hem... 2 | 34
decreased rib number 2 | 59
increased circulating potassiu... 2 | 31
increased circulating sodium l... 2 | 71
increased erythrocyte cell num... 2 | 26
increased grip strength 2 | 83
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased mean corpuscular vol... 2 | 91
increased sacral vertebrae num... 2 | 62
limb grasping 2 | 35
abnormal QRS complex 1 | 25
abnormal allantois morphology 1 | 3
abnormal body wall morphology 1 | 7
abnormal brain morphology 1 | 6
abnormal coat appearance 1 | 25
abnormal cornea morphology 1 | 24
abnormal craniofacial morpholo... 1 | 12
abnormal embryo turning 1 | 15
abnormal eyelid morphology 1 | 6
abnormal facial morphology 1 | 9
abnormal femur morphology 1 | 14
abnormal hindbrain development 1 | 24
abnormal iris morphology 1 | 12
abnormal midbrain development 1 | 22
abnormal neural tube morpholog... 1 | 8
abnormal pelvic girdle bone mo... 1 | 11
abnormal radius morphology 1 | 8
abnormal retinal vasculature m... 1 | 15
abnormal tail bud morphology 1 | 6
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
absent pinna reflex 1 | 21
absent teeth 1 | 4
cataract 1 | 26
cleft palate 1 | 6
decreased Ly6C low monocyte nu... 1 | 23
decreased anxiety-related resp... 1 | 12
decreased cervical vertebrae n... 1 | 12
decreased circulating serum al... 1 | 79
decreased effector memory CD8-... 1 | 24
decreased hemoglobin content 1 | 53
decreased kidney weight 1 | 7
decreased mean corpuscular vol... 1 | 50
decreased thoracic vertebrae n... 1 | 7
decreased vertical activity 1 | 22
edema 1 | 11
embryonic growth retardation 1 | 28
facial cleft 1 | 3
hydroencephaly 1 | 6
hydrometra 1 | 13
increased B cell number 1 | 23
increased Ly6C high monocyte n... 1 | 12
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased bone mineral density 1 | 52
increased mean corpuscular hem... 1 | 25
increased rib number 1 | 41
lethargy 1 | 5
microphthalmia 1 | 15
pale yolk sac 1 | 12
pallor 1 | 13
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
polydactyly 1 | 22
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
shortened ST segment 1 | 9
small thymus 1 | 11
thrombocytopenia 1 | 46

Disease

osteosarcoma 104 | 7,933
ovarian cancer 101 | 8,484
medulloblastoma, large-cell 97 | 6,234
glioblastoma 96 | 5,572
atypical teratoid / rhabdoid tumor 74 | 4,369
psoriasis 74 | 6,685
pilocytic astrocytoma 64 | 3,086
lung cancer 61 | 4,466
primitive neuroectodermal tumor 57 | 3,031
oligodendroglioma 52 | 2,849
invasive ductal carcinoma 49 | 2,950
malignant mesothelioma 47 | 3,162
subependymal giant cell astrocytoma 46 | 2,287
Breast cancer 45 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,956
lung carcinoma 45 | 2,844
pediatric high grade glioma 45 | 2,712
astrocytic glioma 44 | 2,241
Pick disease 42 | 1,893
adult high grade glioma 41 | 2,148
interstitial cystitis 41 | 2,299
ependymoma 40 | 2,514
non-small cell lung cancer 40 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,988
medulloblastoma 38 | 1,524
ulcerative colitis 34 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,289
astrocytoma 31 | 1,493
group 4 medulloblastoma 30 | 1,875
pancreatic cancer 30 | 2,300
ductal carcinoma in situ 29 | 1,745
pituitary cancer 28 | 1,972
spina bifida 28 | 1,064
lung adenocarcinoma 27 | 2,713
Cancer 26 | 2,346
Carcinoma 25 | 2,147
group 3 medulloblastoma 24 | 2,254
posterior fossa group A ependymoma 23 | 1,511
posterior fossa group B ependymoma 23 | 1,530
Multiple myeloma 22 | 1,327
sonic hedgehog group medulloblastoma 22 | 1,482
breast carcinoma 21 | 1,614
acute quadriplegic myopathy 19 | 1,157
cutaneous lupus erythematosus 19 | 1,056
cystic fibrosis 19 | 1,665
primary pancreatic ductal adenocarcinoma 19 | 1,271
tuberculosis 19 | 1,557
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,795
colon cancer 16 | 1,475
juvenile dermatomyositis 16 | 1,189
atypical teratoid/rhabdoid tumor 15 | 1,095
gastric carcinoma 14 | 832
primary Sjogren syndrome 14 | 789
diabetes mellitus 13 | 1,663
Rheumatoid Arthritis 12 | 1,160
dermatomyositis 12 | 933
tuberculosis and treatment for 6 months 12 | 686
active Crohn's disease 11 | 918
adrenocortical carcinoma 11 | 1,427
Parkinson's disease 10 | 364
Waldenstrons macroglobulinemia 10 | 765
aldosterone-producing adenoma 10 | 664
esophageal adenocarcinoma 10 | 737
glioblastoma multiforme 10 | 347
nasopharyngeal carcinoma 10 | 1,056
non primary Sjogren syndrome sicca 10 | 840
Alzheimer's disease 9 | 644
Intellectual disability 9 | 573
progressive supranuclear palsy 9 | 674
Atopic dermatitis 8 | 944
Choroideremia 8 | 13
Chronic Lymphocytic Leukemia 8 | 242
acute myeloid leukemia 8 | 780
mucosa-associated lymphoid tissue lymphoma 8 | 480
sarcoidosis 8 | 358
Duchenne muscular dystrophy 7 | 602
IGA Glomerulonephritis 7 | 454
Myocardial Ischemia 7 | 169
Oculocerebrorenal syndrome 7 | 23
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
fibroadenoma 7 | 557
gastric cancer 7 | 430
hereditary spastic paraplegia 7 | 313
tuberculosis and treatment for 3 months 7 | 327
Down syndrome 6 | 548
Endometriosis 5 | 535
Hermansky-Pudlak syndrome 5 | 43
Joubert syndrome 5 | 61
Multiple Sclerosis 5 | 498
Obesity 5 | 616
Prostatic Neoplasms 5 | 471
Warburg micro syndrome 5 | 19
facioscapulohumeral dystrophy 5 | 286
hepatocellular carcinoma 5 | 532
interstitial lung disease 5 | 291
substance-related disorder 5 | 105
urothelial carcinoma 5 | 318
Polycystic Ovary Syndrome 4 | 332
nephrosclerosis 4 | 329
pancreatic carcinoma 4 | 567

Tissue

Digestive Tract 213 | 18,473
Blood and immune system 212 | 17,995
Male tissues 212 | 17,969
Nervous System 212 | 18,561
Urinary Tract 212 | 18,444
Cardiovascular System 211 | 17,958
Endocrine System 211 | 18,512
Female tissues 211 | 18,647
Liver and Pancreas 211 | 18,136
Respiratory system 211 | 17,484
Skin and soft tissues 210 | 18,115

Target Family

Enzyme 150 | 4,146
Non-IDG 62 | 11,971
Kinase 3 | 634

GO Process

small GTPase mediated signal t... 215 | 215
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ADP-ribosylation factor-like protein 16 ARL16 Tdark Enzyme -0.13389 1.44 17
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.60207 398.9 288
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.40555 28.2 91
Ras and Rab interactor 2 RIN2 Tbio Non-IDG -1.36829 24.1 51
Ras-related protein Rab-43 RAB43 Tbio Enzyme -1.56506 35.9 63
Ras-related protein Rab-5C RAB5C Tbio Enzyme -1.13458 11.1 135
Ras-related protein Rab-27A RAB27A Tbio Enzyme -2.22946 184.9 247
Ras-like protein family member 12 RASL12 Tbio Enzyme -2.73221 568.7 87
Ras-related protein Rab-13 RAB13 Tbio Enzyme -1.35800 26.2 55
Ras-related protein Rab-28 RAB28 Tbio Enzyme -1.12829 14.9 57