Development Level

Tbio 22 | 11,445
Tchem 5 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal embryo size 3 | 220
decreased startle reflex 2 | 75
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
pale yolk sac 2 | 25
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo development 1 | 7
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal limb morphology 1 | 13
abnormal neural tube closure 1 | 46
abnormal response to new envir... 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
cataract 1 | 92
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating glycerol... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
hemorrhage 1 | 23
hydrometra 1 | 53
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
pallor 1 | 34
respiratory system phenotype 1 | 2
scaly skin 1 | 4
small superior vagus ganglion 1 | 74

Disease

ovarian cancer 24 | 8,520
Carcinoma 21 | 11,493
osteosarcoma 18 | 7,950
medulloblastoma, large-cell 15 | 6,241
atypical teratoid / rhabdoid tumor 11 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung cancer 11 | 4,740
psoriasis 11 | 6,694
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
non-small cell lung cancer 10 | 2,890
ependymoma 9 | 4,679
glioblastoma 9 | 5,792
group 3 medulloblastoma 9 | 4,104
Astrocytoma, Pilocytic 8 | 3,081
Breast cancer 8 | 3,578
Cancer 8 | 2,499
Pick disease 8 | 1,894
lung adenocarcinoma 8 | 2,716
lung carcinoma 8 | 2,843
pancreatic cancer 8 | 2,398
Epilepsy 7 | 792
adrenocortical carcinoma 7 | 1,428
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
invasive ductal carcinoma 7 | 2,951
Intellectual disability 6 | 1,016
Kidney cancer 6 | 2,613
Seizures 6 | 596
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
malignant mesothelioma 6 | 3,232
oligodendroglioma 6 | 2,850
tuberculosis 6 | 2,010
Autosomal recessive predisposition 5 | 1,442
Byzanthine arch palate 5 | 194
Dull intelligence 5 | 645
Hypoplastic mandible condyle 5 | 275
Low intelligence 5 | 645
Mandibular hypoplasia 5 | 275
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Micrognathism 5 | 275
Orbital separation excessive 5 | 244
Poor school performance 5 | 645
Short stature 5 | 531
cystic fibrosis 5 | 1,696
primitive neuroectodermal tumor 5 | 3,035
spina bifida 5 | 1,074
ulcerative colitis 5 | 1,819
Anteverted nostril 4 | 191
Cleft Palate 4 | 271
Cognitive delay 4 | 608
Craniofacial Abnormalities 4 | 151
Cryptorchidism 4 | 296
Depressive disorder 4 | 409
Frontal bossing 4 | 157
Global developmental delay 4 | 608
Mental Depression 4 | 333
Mental and motor retardation 4 | 608
Rheumatoid arthritis 4 | 1,191
Small head 4 | 374
Syndactyly 4 | 88
active ulcerative colitis 4 | 764
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
progressive supranuclear palsy 4 | 676
subependymal giant cell astrocytoma 4 | 2,287
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Congenital hypoplasia of penis 3 | 176
Craniosynostosis 3 | 74
Delayed speech and language development 3 | 112
Down syndrome 3 | 499
Dysarthria 3 | 192
High forehead 3 | 102
Language Delay 3 | 112
Long philtrum 3 | 137
Malar flattening 3 | 129
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Multiple myeloma 3 | 1,332
Neurodegenerative disease 3 | 414
Prostate cancer 3 | 175
Schizophrenia 3 | 1,160
Speech Delay 3 | 112
Speech impairment 3 | 112
Tall forehead 3 | 102
Telecanthus 3 | 62
Uranostaphyloschisis 3 | 167
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
gastric carcinoma 3 | 807
juvenile dermatomyositis 3 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962

Tissue

Blood and immune system 30 | 16,909
Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Male tissues 30 | 17,142
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678
Liver and Pancreas 29 | 16,750
Nervous System 28 | 16,725
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 11 | 12,091
Transcription Factor 7 | 1,400
Enzyme 6 | 4,145
Kinase 5 | 634
Ion Channel 1 | 344

GO Process

skeletal system morphogenesis 30 | 30
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Notchless protein homolog 1 NLE1 Tbio Non-IDG -2.69934 437.6 162
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97
Transcription factor 15 TCF15 Tbio Transcription Factor -2.45759 267.3 70
Intraflagellar transport protein 140 homolog IFT140 Tbio Non-IDG -1.42568 23.3 45
Zinc finger protein 84 ZNF84 Tdark Transcription Factor -0.57958 3.24 27
SH3 and PX domain-containing protein 2B SH3PXD2B Tbio Non-IDG -1.72872 53.3 71
Homeobox protein Hox-D8 HOXD8 Tbio Transcription Factor -1.06607 11.3 190
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.13063 1294.7 1785
Ankyrin repeat domain-containing protein 11 ANKRD11 Tbio Non-IDG -2.55588 339.7 93