Development Level

Tbio 111 | 11,445
Tchem 16 | 1,598
Tclin 6 | 613
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal behavior 4 | 298
abnormal heart morphology 4 | 162
decreased body weight 4 | 161
short tibia 4 | 97
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
abnormal femur morphology 3 | 14
decreased erythrocyte cell num... 3 | 62
enlarged heart 3 | 210
increased heart weight 3 | 62
abnormal bone mineralization 2 | 38
abnormal joint morphology 2 | 23
abnormal radius morphology 2 | 8
abnormal tibia morphology 2 | 14
abnormal ulna morphology 2 | 8
decreased body length 2 | 101
decreased circulating amylase ... 2 | 28
decreased circulating aspartat... 2 | 34
decreased circulating calcium ... 2 | 36
decreased circulating phosphat... 2 | 27
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
impaired righting response 2 | 26
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased mean corpuscular hem... 2 | 36
increased or absent threshold ... 2 | 101
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal head morphology 1 | 10
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pelvic girdle bone mo... 1 | 12
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal stomach morphology 1 | 10
abnormal tail morphology 1 | 25
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased B cell number 1 | 9
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
long tail 1 | 1
mammalian phenotype 1 | 17
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
polycystic kidney 1 | 15
thick tail 1 | 1
vertebral fusion 1 | 23

Disease

Carcinoma 95 | 11,493
ovarian cancer 76 | 8,520
psoriasis 68 | 6,694
osteosarcoma 67 | 7,950
glioblastoma 58 | 5,792
lung cancer 57 | 4,740
medulloblastoma, large-cell 55 | 6,241
Breast cancer 51 | 3,578
Cancer 48 | 2,499
atypical teratoid / rhabdoid tumor 47 | 5,112
Short stature 44 | 531
ependymoma 43 | 4,679
pancreatic cancer 43 | 2,398
adult high grade glioma 41 | 3,801
malignant mesothelioma 39 | 3,232
non-small cell lung cancer 38 | 2,890
invasive ductal carcinoma 37 | 2,951
interstitial cystitis 36 | 2,312
lung adenocarcinoma 36 | 2,716
lung carcinoma 34 | 2,843
Astrocytoma, Pilocytic 32 | 3,081
group 3 medulloblastoma 31 | 4,104
Kidney cancer 29 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
ductal carcinoma in situ 28 | 1,745
breast carcinoma 27 | 1,638
pituitary cancer 27 | 1,972
Autosomal recessive predisposition 26 | 1,442
Brachydactyly 26 | 156
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
oligodendroglioma 25 | 2,850
Acquired scoliosis 24 | 281
Curvature of spine 24 | 282
colon cancer 24 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
primitive neuroectodermal tumor 23 | 3,035
Craniofacial Abnormalities 22 | 151
ulcerative colitis 22 | 1,819
Muscle hypotonia 21 | 571
Osteoporosis 21 | 363
gastric carcinoma 21 | 807
Cleft Palate 20 | 271
Hypoplastic mandible condyle 20 | 275
Mandibular hypoplasia 20 | 275
Micrognathism 20 | 275
Osteoarthritis 20 | 184
cystic fibrosis 20 | 1,696
primary pancreatic ductal adenocarcinoma 20 | 1,109
Concave bridge of nose 19 | 195
Depressed nasal bridge 19 | 195
Depressed nasal root/bridge 19 | 195
Frontal bossing 19 | 157
adrenocortical carcinoma 19 | 1,428
juvenile dermatomyositis 19 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
Hypotrophic malar bone 18 | 129
Intellectual disability 18 | 1,016
Malar flattening 18 | 129
Schizophrenia 18 | 1,160
Bilateral fifth finger clinodactyly 17 | 110
Curvature of little finger 17 | 110
astrocytic glioma 17 | 2,597
esophageal adenocarcinoma 17 | 737
group 4 medulloblastoma 17 | 1,855
nasopharyngeal carcinoma 17 | 1,058
subependymal giant cell astrocytoma 17 | 2,287
Cognitive delay 16 | 608
Delayed bone age 16 | 136
Duchenne muscular dystrophy 16 | 601
Dull intelligence 16 | 645
Global developmental delay 16 | 608
Joint hyperflexibility 16 | 78
Low intelligence 16 | 645
Mental Retardation 16 | 645
Mental and motor retardation 16 | 608
Mental deficiency 16 | 645
Orbital separation excessive 16 | 244
Platyspondyly 16 | 56
Poor school performance 16 | 645
acute quadriplegic myopathy 16 | 1,158
hearing impairment 16 | 199
Congenital deafness 15 | 185
Cryptorchidism 15 | 296
Deafness 15 | 198
Genu varum 15 | 29
Hearing Loss, Partial 15 | 185
Micromelia 15 | 58
Degenerative polyarthritis 14 | 115
Hypoplastic feet 14 | 66
Pick disease 14 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
diabetes mellitus 14 | 1,728
Atopic dermatitis 13 | 952
Obesity 13 | 678
Short distal phalanges 13 | 50
Short hands 13 | 50
Short metacarpal 13 | 43
tuberculosis 13 | 2,010
Failure to gain weight 12 | 365
Rheumatoid arthritis 12 | 1,191

Tissue

Endocrine System 129 | 18,159
Digestive Tract 128 | 17,369
Female tissues 127 | 17,400
Skin and soft tissues 126 | 17,230
Male tissues 124 | 17,142
Nervous System 123 | 16,725
Urinary Tract 120 | 16,678
Blood and immune system 119 | 16,909
Liver and Pancreas 119 | 16,750
Respiratory system 114 | 16,393
Cardiovascular System 109 | 15,192

Target Family

Non-IDG 80 | 12,091
Transcription Factor 26 | 1,400
Enzyme 15 | 4,145
Kinase 8 | 634
Epigenetic 4 | 242
GPCR 2 | 408
Nuclear Receptor 1 | 48

GO Process

skeletal system development 136 | 136
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Intraflagellar transport protein 25 homolog HSPB11 Tbio Non-IDG -1.40552 26.1 61
Hyaluronan and proteoglycan link protein 4 HAPLN4 Tbio Non-IDG -0.76903 6.57 156
Collagen alpha-1(XII) chain COL12A1 Tbio Non-IDG -1.36571 21.4 38
Treacle protein TCOF1 Tbio Non-IDG -3.44117 2743.5 131
Zinc finger transcription factor Trps1 TRPS1 Tbio Transcription Factor -1.98756 107.0 69
T-box transcription factor TBX3 TBX3 Tbio Transcription Factor -2.42253 255.6 328
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283
Ribosomal protein S6 kinase alpha-3 RPS6KA3 Tchem Kinase -2.50143 325.4 425
Transcription factor HES-7 HES7 Tbio Transcription Factor -1.36047 22.6 144