Development Level

Tbio 33 | 11,178
Tchem 9 | 1,885
Tdark 3 | 6,569

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal cecum morphology 1 | 7
abnormal embryo size 1 | 220
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
female infertility 1 | 60
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating total pr... 1 | 28
male infertility 1 | 123
megacolon 1 | 2
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 29 | 11,192
ovarian cancer 22 | 8,297
glioblastoma 21 | 5,635
medulloblastoma, large-cell 18 | 6,086
osteosarcoma 18 | 7,766
psoriasis 17 | 6,514
lung cancer 16 | 4,607
adult high grade glioma 15 | 3,701
Cancer 14 | 2,388
Astrocytoma, Pilocytic 13 | 3,006
Breast cancer 13 | 3,469
atypical teratoid / rhabdoid tumor 13 | 4,971
non-small cell lung cancer 13 | 2,799
ependymoma 12 | 4,559
lung carcinoma 12 | 2,755
invasive ductal carcinoma 11 | 2,867
lung adenocarcinoma 11 | 2,627
Pick disease 10 | 1,856
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,204
group 3 medulloblastoma 9 | 4,002
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,872
Kidney cancer 8 | 2,548
acute quadriplegic myopathy 8 | 1,133
colon cancer 8 | 1,428
ductal carcinoma in situ 8 | 1,686
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,902
malignant mesothelioma 8 | 3,135
subependymal giant cell astrocytoma 8 | 2,230
dermatomyositis 7 | 941
pancreatic cancer 7 | 2,322
Autosomal recessive predisposition 6 | 1,407
Melanoma 6 | 689
Myopathy 6 | 185
Schizophrenia 6 | 1,136
breast carcinoma 6 | 1,589
diabetes mellitus 6 | 1,683
group 4 medulloblastoma 6 | 1,806
interstitial cystitis 6 | 2,237
oligodendroglioma 6 | 2,768
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,911
pituitary cancer 6 | 1,915
primitive neuroectodermal tumor 6 | 2,957
ulcerative colitis 6 | 1,765
Dull intelligence 5 | 634
Hypertrophic Cardiomyopathy 5 | 115
Hypoplastic mandible condyle 5 | 273
Intellectual disability 5 | 998
Low intelligence 5 | 634
Mandibular hypoplasia 5 | 273
Mental Retardation 5 | 634
Mental deficiency 5 | 634
Micrognathism 5 | 273
Muscle Weakness 5 | 168
Poor school performance 5 | 634
Short stature 5 | 514
adrenocortical carcinoma 5 | 1,385
tuberculosis 5 | 1,963
Acquired scoliosis 4 | 274
Alzheimer's disease 4 | 640
Amyotrophic lateral sclerosis 4 | 437
Cleft Palate 4 | 265
Cognitive delay 4 | 596
Concave bridge of nose 4 | 191
Cryptorchidism 4 | 287
Curvature of spine 4 | 275
Depressed nasal bridge 4 | 191
Depressed nasal root/bridge 4 | 191
Duchenne muscular dystrophy 4 | 587
Global developmental delay 4 | 596
Highly variable severity 4 | 149
Mental and motor retardation 4 | 596
Orbital separation excessive 4 | 240
Rhabdomyosarcoma 4 | 39
Skin cancer 4 | 451
Small head 4 | 366
Variable expressivity 4 | 149
X-linked cerebral adrenoleukodystrophy 4 | 114
astrocytic glioma 4 | 2,530
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 492
cutaneous lupus erythematosus 4 | 1,016
primary pancreatic ductal adenocarcinoma 4 | 1,071
progressive supranuclear palsy 4 | 656
Arthritis 3 | 276
Bipolar Disorder 3 | 646
Byzanthine arch palate 3 | 194
Congenital Epicanthus 3 | 175
Epilepsy 3 | 775
Glaucoma 3 | 232
Myocardial Ischemia 3 | 162
Uranostaphyloschisis 3 | 162
Ventricular Septal Defects 3 | 113
Waldenstrons macroglobulinemia 3 | 742
astrocytoma 3 | 1,113
chronic rhinosinusitis 3 | 505
fibroadenoma 3 | 538
juvenile dermatomyositis 3 | 1,147
nasopharyngeal carcinoma 3 | 1,024
pediatric high grade glioma 3 | 1,035
primary Sjogren syndrome 3 | 710
spina bifida 3 | 1,053

Tissue

Digestive Tract 44 | 17,369
Male tissues 44 | 17,142
Skin and soft tissues 44 | 17,230
Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Blood and immune system 40 | 16,909
Liver and Pancreas 40 | 16,750
Urinary Tract 40 | 16,678
Nervous System 39 | 16,725
Cardiovascular System 35 | 15,192
Respiratory system 35 | 16,393

Target Family

Non-IDG 23 | 12,091
Transcription Factor 13 | 1,400
Enzyme 3 | 4,145
Kinase 3 | 634
Epigenetic 1 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

GO Process

skeletal muscle tissue develop... 45 | 45
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nephrin NPHS1 Tbio Non-IDG -3.16031 1396.4 555
Transcription cofactor vestigial-like protein 2 VGLL2 Tbio Non-IDG -0.80543 8.67 155
Calsequestrin-1 CASQ1 Tbio Non-IDG -1.96476 86.8 103
Glycerophosphocholine phosphodiesterase GPCPD1 GPCPD1 Tdark Enzyme -1.71900 49.0 17
Cofilin-2 CFL2 Tbio Non-IDG -1.50787 29.3 253
Homeobox protein SIX4 SIX4 Tbio Transcription Factor -2.31722 197.8 141
SRSF protein kinase 3 SRPK3 Tchem Kinase -0.48565 2.96 103
Cysteine and glycine-rich protein 3 CSRP3 Tbio Non-IDG -2.00418 105.2 236
Myosin light chain 6B MYL6B Tdark Non-IDG -0.48723 2.69 127
E3 ubiquitin-protein ligase NEURL1 NEURL1 Tbio Enzyme -1.09204 13.1 165