Development Level

Tbio 37 | 10,625
Tchem 6 | 1,890
Tdark 4 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
embryonic lethality prior to t... 3 | 187
decreased startle reflex 2 | 48
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
abnormal spinal cord morpholog... 1 | 8
absent seminal vesicle 1 | 2
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating insulin ... 1 | 75
decreased erythrocyte cell num... 1 | 43
decreased lean body mass 1 | 195
embryonic lethality prior to o... 1 | 148
female infertility 1 | 34
increased fasted circulating g... 1 | 68
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased total body fat amoun... 1 | 57
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82

Disease

osteosarcoma 17 | 7,933
glioblastoma 16 | 5,572
ovarian cancer 16 | 8,484
Cancer 15 | 2,346
lung cancer 14 | 4,466
psoriasis 14 | 6,685
medulloblastoma, large-cell 13 | 6,234
group 4 medulloblastoma 12 | 1,875
malignant mesothelioma 12 | 3,162
Breast cancer 11 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
non-small cell lung cancer 10 | 2,798
oligodendroglioma 10 | 2,849
pituitary cancer 10 | 1,972
primitive neuroectodermal tumor 10 | 3,031
Rheumatoid Arthritis 9 | 1,160
ependymoma 9 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
invasive ductal carcinoma 9 | 2,950
lung adenocarcinoma 9 | 2,713
lung carcinoma 9 | 2,844
astrocytoma 8 | 1,493
atypical teratoid / rhabdoid tumor 8 | 4,369
breast carcinoma 8 | 1,614
ulcerative colitis 8 | 2,087
adrenocortical carcinoma 7 | 1,427
colon cancer 7 | 1,475
interstitial cystitis 7 | 2,299
acute quadriplegic myopathy 6 | 1,157
astrocytic glioma 6 | 2,241
gastric carcinoma 6 | 832
subependymal giant cell astrocytoma 6 | 2,287
Carcinoma 5 | 2,147
Down syndrome 5 | 548
Mammary Neoplasms 5 | 410
Multiple myeloma 5 | 1,327
Myopathy 5 | 128
cystic fibrosis 5 | 1,665
dermatomyositis 5 | 933
inflammatory breast cancer 5 | 404
juvenile dermatomyositis 5 | 1,189
pancreatic cancer 5 | 2,300
pediatric high grade glioma 5 | 2,712
pilocytic astrocytoma 5 | 3,086
posterior fossa group A ependymoma 5 | 1,511
primary Sjogren syndrome 5 | 789
Cardiomyopathies 4 | 90
Endometriosis 4 | 535
Waldenstrons macroglobulinemia 4 | 765
active ulcerative colitis 4 | 477
acute myeloid leukemia 4 | 780
aldosterone-producing adenoma 4 | 664
diabetes mellitus 4 | 1,663
ductal carcinoma in situ 4 | 1,745
nephrosclerosis 4 | 329
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
periodontitis 4 | 269
pterygium 4 | 74
urothelial carcinoma 4 | 318
Alzheimer's disease 3 | 644
Duchenne muscular dystrophy 3 | 602
Juvenile arthritis 3 | 124
Liver carcinoma 3 | 217
Neuropathy 3 | 210
Osteoporosis 3 | 257
Parkinson's disease 3 | 364
Pick disease 3 | 1,893
Precursor Cell Lymphoblastic Leukemia Lymphoma 3 | 42
Reperfusion Injury 3 | 84
Skeletal muscle neoplasm 3 | 8
Vascular disease 3 | 281
adult high grade glioma 3 | 2,148
atypical teratoid/rhabdoid tumor 3 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,056
gastric cancer 3 | 430
group 3 medulloblastoma 3 | 2,254
hepatocellular carcinoma 3 | 532
medulloblastoma 3 | 1,524
nasopharyngeal carcinoma 3 | 1,056
nervous system disorder 3 | 53
non primary Sjogren syndrome sicca 3 | 840
non-small cell lung carcinoma 3 | 413
sonic hedgehog group medulloblastoma 3 | 1,482
spina bifida 3 | 1,064
tuberculosis 3 | 1,557
Atopic dermatitis 2 | 944
Brain Ischemia 2 | 87
Cerebrovascular disease 2 | 231
Heart disease 2 | 279
Hypertension 2 | 287
Migraine 2 | 79
Peripheral Neuropathy 2 | 303
Prostatic Neoplasms 2 | 471
active Crohn's disease 2 | 918
esophageal adenocarcinoma 2 | 737
limb girdle muscular dystrophy 2I 2 | 56
primary pancreatic ductal adenocarcinoma 2 | 1,271

Tissue

Female tissues 47 | 18,647
Digestive Tract 46 | 18,473
Endocrine System 46 | 18,512
Liver and Pancreas 46 | 18,136
Nervous System 46 | 18,561
Skin and soft tissues 46 | 18,115
Male tissues 45 | 17,969
Urinary Tract 45 | 18,444
Blood and immune system 44 | 17,995
Cardiovascular System 44 | 17,958
Respiratory system 43 | 17,484

Target Family

Transcription Factor 27 | 1,400
Non-IDG 17 | 11,971
Enzyme 1 | 4,146
Epigenetic 1 | 242
Kinase 1 | 634

GO Process

skeletal muscle cell different... 47 | 47
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Basic helix-loop-helix transcription factor scleraxis SCX Tbio Transcription Factor -2.80657 344.1 42
Emerin EMD Tbio Non-IDG -2.77469 617.6 238
Krueppel-like factor 5 KLF5 Tchem Transcription Factor -2.15588 189.7 186
Elongation factor 2 EEF2 Tchem Non-IDG -2.93803 911.5 347
COP9 signalosome complex subunit 2 COPS2 Tbio Non-IDG -0.87368 7.80 293
Eomesodermin homolog EOMES Tbio Transcription Factor -2.25701 201.9 256
LEM domain-containing protein 2 LEMD2 Tdark Non-IDG -0.42325 3.73 86
Myogenic factor 5 MYF5 Tbio Transcription Factor -2.48491 283.8 279
Histone-lysine N-methyltransferase SMYD1 SMYD1 Tbio Epigenetic -1.23315 17.8 123