Development Level

Tbio 82 | 10,625
Tchem 7 | 1,890
Tclin 3 | 602
Tdark 3 | 7,003

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 7 | 633
abnormal behavior 3 | 226
decreased bone mineral density 3 | 126
preweaning lethality, incomple... 3 | 260
abnormal embryo size 2 | 112
abnormal retinal pigmentation 2 | 61
abnormal sleep behavior 2 | 63
decreased basophil cell number 2 | 11
decreased circulating glucose ... 2 | 121
edema 2 | 11
impaired glucose tolerance 2 | 52
increased circulating potassiu... 2 | 31
increased or absent threshold ... 2 | 128
prenatal lethality prior to he... 2 | 64
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal eye morphology 1 | 38
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal locomotor activation 1 | 26
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal spinal cord morpholog... 1 | 8
abnormal startle reflex 1 | 14
abnormal tail morphology 1 | 17
abnormal testis morphology 1 | 30
absent startle reflex 1 | 15
absent vibrissae 1 | 14
cataract 1 | 26
craniofacial phenotype 1 | 9
cyanosis 1 | 6
decreased B-2 B cell number 1 | 2
decreased bone mineral content 1 | 157
decreased circulating chloride... 1 | 32
decreased circulating insulin ... 1 | 75
decreased circulating potassiu... 1 | 17
decreased coping response 1 | 5
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
enlarged pancreas 1 | 1
enlarged uterus 1 | 3
hemorrhage 1 | 12
herniated abdominal wall 1 | 4
hydrometra 1 | 13
hydrops fetalis 1 | 22
hyperactivity 1 | 108
hypoactivity 1 | 89
immune system phenotype 1 | 17
impaired righting response 1 | 19
increased B-1a cell number 1 | 2
increased body length 1 | 20
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating free fat... 1 | 17
increased circulating glucose ... 1 | 16
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased rib number 1 | 41
increased vertical activity 1 | 18
male infertility 1 | 62
pale yolk sac 1 | 12
persistence of hyaloid vascula... 1 | 22
prenatal lethality 1 | 16
respiratory system phenotype 1 | 2
short tibia 1 | 82
small superior vagus ganglion 1 | 20
small testis 1 | 37

Disease

ovarian cancer 52 | 8,484
glioblastoma 46 | 5,572
psoriasis 44 | 6,685
osteosarcoma 43 | 7,933
lung cancer 41 | 4,466
medulloblastoma, large-cell 38 | 6,234
Carcinoma 35 | 2,147
atypical teratoid / rhabdoid tumor 35 | 4,369
non-small cell lung cancer 35 | 2,798
lung adenocarcinoma 34 | 2,713
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,289
interstitial cystitis 31 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,988
lung carcinoma 29 | 2,844
Cancer 27 | 2,346
pilocytic astrocytoma 25 | 3,086
invasive ductal carcinoma 24 | 2,950
malignant mesothelioma 24 | 3,162
pituitary cancer 24 | 1,972
primitive neuroectodermal tumor 24 | 3,031
group 4 medulloblastoma 23 | 1,875
oligodendroglioma 23 | 2,849
pancreatic cancer 23 | 2,300
pediatric high grade glioma 23 | 2,712
subependymal giant cell astrocytoma 23 | 2,287
Breast cancer 22 | 3,094
ductal carcinoma in situ 21 | 1,745
primary pancreatic ductal adenocarcinoma 18 | 1,271
ulcerative colitis 18 | 2,087
astrocytic glioma 17 | 2,241
ependymoma 17 | 2,514
adrenocortical carcinoma 16 | 1,427
esophageal adenocarcinoma 16 | 737
posterior fossa group A ependymoma 15 | 1,511
spina bifida 15 | 1,064
adult high grade glioma 14 | 2,148
Pick disease 13 | 1,893
cutaneous lupus erythematosus 13 | 1,056
cystic fibrosis 13 | 1,665
Rheumatoid Arthritis 12 | 1,160
breast carcinoma 12 | 1,614
colon cancer 12 | 1,475
medulloblastoma 12 | 1,524
tuberculosis 12 | 1,557
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
Kidney disease 10 | 396
gastric carcinoma 10 | 832
atypical teratoid/rhabdoid tumor 9 | 1,095
juvenile dermatomyositis 9 | 1,189
nephrosclerosis 9 | 329
posterior fossa group B ependymoma 9 | 1,530
sonic hedgehog group medulloblastoma 9 | 1,482
Atopic dermatitis 8 | 944
Colorectal Neoplasms 8 | 217
Down syndrome 8 | 548
Duchenne muscular dystrophy 8 | 602
astrocytoma 8 | 1,493
group 3 medulloblastoma 8 | 2,254
primary Sjogren syndrome 8 | 789
Alzheimer's disease 7 | 644
Mammary Neoplasms 7 | 410
Multiple Sclerosis 7 | 498
diabetes mellitus 7 | 1,663
interstitial lung disease 7 | 291
Osteoporosis 6 | 257
Prostatic Neoplasms 6 | 471
Stomach Neoplasms 6 | 282
active Crohn's disease 6 | 918
dermatomyositis 6 | 933
tuberculosis and treatment for 6 months 6 | 686
Autistic Disorder 5 | 320
Barrett's esophagus 5 | 183
Endometriosis 5 | 535
Hypersensitivity reaction type II disease 5 | 235
Intellectual disability 5 | 573
Neutropenia 5 | 78
Obesity 5 | 616
Schizophrenia 5 | 501
Vascular disease 5 | 281
acute myeloid leukemia 5 | 780
acute quadriplegic myopathy 5 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
nasopharyngeal carcinoma 5 | 1,056
Adenoma 4 | 165
Arrhythmogenic right ventricular cardiomyopathy 4 | 27
Cardiomyopathy 4 | 110
Hypotrichosis 4 | 29
Liver disease 4 | 219
Mammary Neoplasms, Experimental 4 | 150
Multiple myeloma 4 | 1,327
Neoplasm Invasiveness 4 | 127
Neoplasm Metastasis 4 | 138
Nerve Degeneration 4 | 73
chronic lymphosyte leukemia 4 | 232
hepatocellular carcinoma 4 | 532
non primary Sjogren syndrome sicca 4 | 840
non-inflammatory breast cancer 4 | 208
ovarian neoplasm 4 | 97
urothelial carcinoma 4 | 318

Tissue

Blood and immune system 94 | 17,995
Cardiovascular System 94 | 17,958
Female tissues 94 | 18,647
Liver and Pancreas 94 | 18,136
Urinary Tract 94 | 18,444
Digestive Tract 93 | 18,473
Endocrine System 93 | 18,512
Nervous System 93 | 18,561
Skin and soft tissues 93 | 18,115
Male tissues 92 | 17,969
Respiratory system 91 | 17,484

Target Family

Non-IDG 81 | 11,971
Enzyme 6 | 4,146
Kinase 3 | 634
Ion Channel 2 | 341
Transcription Factor 2 | 1,400
GPCR 1 | 406

GO Process

single organismal cell-cell ad... 95 | 95
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ropporin-1B ROPN1B Tbio Non-IDG 1.00 0.10 52
Sialoadhesin SIGLEC1 Tbio Non-IDG -2.22508 195.6 309
Podoplanin PDPN Tbio Non-IDG -3.28348 1987.7 771
Nephrocystin-4 NPHP4 Tbio Non-IDG -1.39275 26.0 48
Nephrocystin-1 NPHP1 Tbio Non-IDG -1.70748 50.8 88
Neuroligin-2 NLGN2 Tbio Enzyme -1.63131 44.0 67
Integrin alpha-6 ITGA6 Tchem Non-IDG -2.25486 168.8 756
Intercellular adhesion molecule 2 ICAM2 Tbio Non-IDG -2.18550 142.0 532
Annexin A9 ANXA9 Tbio Non-IDG -0.87207 9.87 135
Inducible T-cell costimulator ICOS Tbio Non-IDG -1.41376 31.7 495