Development Level

Tbio 36 | 10,625
Tdark 10 | 7,003
Tchem 6 | 1,890
Tclin 1 | 602

IMPC Term

decreased circulating amylase ... 2 | 24
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal embryo size 1 | 112
abnormal forelimb morphology 1 | 2
abnormal gait 1 | 51
abnormal locomotor activation 1 | 26
abnormal response to new envir... 1 | 8
corneal vascularization 1 | 5
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating triglyce... 1 | 83
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
hyperactivity 1 | 108
hypoactivity 1 | 89
increased circulating chloride... 1 | 43
increased lean body mass 1 | 107
limb grasping 1 | 35
small kidney 1 | 10
small superior vagus ganglion 1 | 20

Disease

psoriasis 20 | 6,685
osteosarcoma 17 | 7,933
ovarian cancer 16 | 8,484
malignant mesothelioma 14 | 3,162
medulloblastoma, large-cell 14 | 6,234
glioblastoma 12 | 5,572
Cancer 11 | 2,346
Carcinoma 10 | 2,147
lung cancer 10 | 4,466
Breast cancer 9 | 3,094
group 3 medulloblastoma 9 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
adult high grade glioma 8 | 2,148
atypical teratoid / rhabdoid tumor 8 | 4,369
invasive ductal carcinoma 8 | 2,950
pancreatic cancer 8 | 2,300
Infertility 7 | 163
Male infertility 7 | 170
group 4 medulloblastoma 7 | 1,875
interstitial cystitis 7 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
nasopharyngeal carcinoma 7 | 1,056
non-small cell lung cancer 7 | 2,798
posterior fossa group B ependymoma 7 | 1,530
primitive neuroectodermal tumor 7 | 3,031
atypical teratoid/rhabdoid tumor 6 | 1,095
breast carcinoma 6 | 1,614
colon cancer 6 | 1,475
cutaneous lupus erythematosus 6 | 1,056
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
lung adenocarcinoma 6 | 2,713
pituitary cancer 6 | 1,972
Atopic dermatitis 5 | 944
ductal carcinoma in situ 5 | 1,745
oligodendroglioma 5 | 2,849
subependymal giant cell astrocytoma 5 | 2,287
Endometriosis 4 | 535
Multiple myeloma 4 | 1,327
adrenocortical carcinoma 4 | 1,427
diabetes mellitus 4 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pilocytic astrocytoma 4 | 3,086
Azoospermia 3 | 89
Colorectal Neoplasms 3 | 217
Cryptorchidism 3 | 67
Neurodegenerative disease 3 | 383
Pick disease 3 | 1,893
acute myeloid leukemia 3 | 780
astrocytic glioma 3 | 2,241
astrocytoma 3 | 1,493
chronic rhinosinusitis 3 | 512
cystic fibrosis 3 | 1,665
ependymoma 3 | 2,514
medulloblastoma 3 | 1,524
pancreatic carcinoma 3 | 567
pediatric high grade glioma 3 | 2,712
sonic hedgehog group medulloblastoma 3 | 1,482
Amyotrophic Lateral Sclerosis 2 | 431
Aplastic anemia 2 | 18
Bipolar Disorder 2 | 266
Brachydactyly 2 | 52
Crohn's disease 2 | 304
Endometrial Neoplasms 2 | 50
Female Urogenital Diseases 2 | 18
Gonadoblastoma 2 | 27
Hydrolethalus syndrome 2 | 128
Hypertension 2 | 287
Hypertensive disease 2 | 193
Hypogonadism 2 | 70
Inflammatory Bowel Diseases 2 | 87
Kidney disease 2 | 396
Liver carcinoma 2 | 217
Mammary Neoplasms 2 | 410
Neoplasm Recurrence, Local 2 | 23
Polycystic Ovary Syndrome 2 | 332
Primary ciliary dyskinesia 2 | 73
acute quadriplegic myopathy 2 | 1,157
dermatomyositis 2 | 933
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 832
lung carcinoma 2 | 2,844
non-inflammatory breast cancer 2 | 208
posterior fossa group A ependymoma 2 | 1,511
primary pancreatic ductal adenocarcinoma 2 | 1,271
tuberculosis 2 | 1,557
tuberculosis and treatment for 6 months 2 | 686
uncontrolled asthma 2 | 67
Allergic conjunctivitis 1 | 25
Atypical Hemolytic Uremic Syndrome 1 | 9
Chondroblastoma 1 | 7
Exanthema subitum 1 | 3
Insulin Resistance 1 | 48
Invasive Ductal Breast Carcinoma 1 | 9
Lower Extremity Deformities, Congenital 1 | 2
Mobius syndrome 1 | 7
Mucinous Adenocarcinoma 1 | 4
Myofascial pain syndrome 1 | 7
Subacute sclerosing panencephalitis 1 | 10
Vertical talus, congenital 1 | 1
hemolytic-uremic syndrome 1 | 28

Tissue

Endocrine System 52 | 18,512
Urinary Tract 51 | 18,444
Female tissues 50 | 18,647
Skin and soft tissues 48 | 18,115
Digestive Tract 47 | 18,473
Liver and Pancreas 47 | 18,136
Male tissues 47 | 17,969
Nervous System 47 | 18,561
Blood and immune system 46 | 17,995
Cardiovascular System 46 | 17,958
Respiratory system 40 | 17,484

Target Family

Non-IDG 28 | 11,971
Enzyme 9 | 4,146
Transcription Factor 7 | 1,400
Ion Channel 3 | 341
oGPCR 2 | 421
Kinase 1 | 634
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38
Transporter 1 | 473

GO Process

single fertilization 53 | 53
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lymphoid-restricted membrane protein LRMP Tbio Non-IDG -1.17754 15.9 54
Inactive ribonuclease-like protein 10 RNASE10 Tdark Enzyme -0.65321 4.33 16
Forkhead box protein L2 FOXL2 Tbio Transcription Factor -2.76212 610.7 220
Izumo sperm-egg fusion protein 1 IZUMO1 Tbio Non-IDG -2.11628 138.3 78
Histone H3.3 H3F3B Tbio Non-IDG -2.06154 100.6 415
Epididymal-specific lipocalin-6 LCN6 Tbio Non-IDG -0.96932 8.77 69
Sperm-egg fusion protein Juno IZUMO1R Tbio Non-IDG -1.63918 46.1 209
Membrane cofactor protein CD46 Tbio Non-IDG -2.90635 849.0 564
Solute carrier family 22 member 16 SLC22A16 Tchem Transporter -1.39164 26.5 101
Olfactory receptor 10J1 OR10J1 Tdark oGPCR 0.00000 38