Development Level

Tchem 18 | 1,598
Tbio 5 | 11,445
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 6 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal retina morphology 1 | 71
abnormal startle reflex 1 | 15
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased caudal vertebrae num... 1 | 7
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 22 | 11,493
ovarian cancer 14 | 8,520
osteosarcoma 13 | 7,950
lung cancer 10 | 4,740
medulloblastoma, large-cell 10 | 6,241
psoriasis 10 | 6,694
malignant mesothelioma 9 | 3,232
non-small cell lung cancer 9 | 2,890
Cancer 8 | 2,499
glioblastoma 8 | 5,792
Kidney cancer 7 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Breast cancer 6 | 3,578
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
lung carcinoma 6 | 2,843
pancreatic cancer 6 | 2,398
Astrocytoma, Pilocytic 5 | 3,081
astrocytic glioma 5 | 2,597
primitive neuroectodermal tumor 5 | 3,035
Blastic phase chronic myeloid leukemia 4 | 58
Chronic Myelocytic Leukemia Accelerated Phase 4 | 59
group 4 medulloblastoma 4 | 1,855
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic carcinoma 4 | 562
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Adenocarcinoma of pancreas 3 | 14
Autosomal recessive predisposition 3 | 1,442
Gastrointestinal stromal tumor 3 | 62
Hamman-Rich syndrome 3 | 34
Pancreatic Neuroendocrine Tumor 3 | 45
Renal Cell Carcinoma 3 | 214
Rheumatoid arthritis 3 | 1,191
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
oligodendroglioma 3 | 2,850
spina bifida 3 | 1,074
Acute myeloid leukemia, disease 2 | 30
Adenocarcinoma of lung 2 | 142
Aggressive systemic mastocytosis 2 | 20
Ambiguous Genitalia 2 | 24
Amyotrophic lateral sclerosis 2 | 451
HER2-positive carcinoma of breast 2 | 21
Hypertension 2 | 396
Hypertensive disease 2 | 292
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Mast cell leukemia 2 | 13
Melanoma 2 | 711
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
gastric cancer 2 | 459
juvenile dermatomyositis 2 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 416
progressive supranuclear palsy 2 | 676
ulcerative colitis 2 | 1,819
Asphyxiating thoracic dystrophy 1 | 44
Breast adenoma 1 | 4
Delayed Puberty 1 | 97
Gonadal Dysgenesis 1 | 28
Gonadal Dysgenesis, Mixed 1 | 19
Hypokalemia 1 | 52
Increased susceptibility to bacterial infections 1 | 42
Low serum estradiol levels 1 | 22
Medium chain acyl-CoA dehydrogenase deficiency 1 | 13
Metabolic acidosis 1 | 90
Nonorganic psychosis 1 | 84
Primary hypogonadism 1 | 37
Primary physiologic amenorrhea 1 | 55
Prone to bacterial infection 1 | 42
Pure gonadal dysgenesis 1 | 19
Recurrent bacterial infection 1 | 42
Retinitis pigmentosa 23 1 | 27
Sensenbrenner syndrome 1 | 17
Short ribs 1 | 30
Small testicle 1 | 75
Sparse pubic hair 1 | 31
Streak ovary 1 | 15
Testicular Germ Cell Tumor 1 | 14
Warts 1 | 10
axial spondyloarthropathy 1 | 28
non-syndromic X-linked intellectual disability 1 | 20

Tissue

Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Male tissues 24 | 17,142
Digestive Tract 23 | 17,369
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Cardiovascular System 22 | 15,192
Liver and Pancreas 22 | 16,750
Nervous System 22 | 16,725
Urinary Tract 22 | 16,678
Blood and immune system 20 | 16,909

Target Family

Kinase 22 | 634
Non-IDG 2 | 12,091

GO Process

signal transduction by protein... 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase OSR1 OXSR1 Tbio Kinase -0.99836 9.44 355
Serine/threonine-protein kinase 10 STK10 Tchem Kinase -2.33522 213.0 236
Serine/threonine-protein kinase Nek1 NEK1 Tchem Kinase -1.62443 47.0 85
Mitogen-activated protein kinase kinase kinase 19 MAP3K19 Tchem Kinase 0.08 1.74 33
Serine/threonine-protein kinase Nek4 NEK4 Tbio Kinase -1.15584 11.5 142
Proto-oncogene tyrosine-protein kinase ROS ROS1 Tchem Kinase -2.50073 301.7 343
Dual specificity mitogen-activated protein kinase kinase 4 MAP2K4 Tchem Kinase -2.43646 236.7 998
Serine/threonine-protein kinase SBK2 SBK2 Tdark Kinase -0.45230 2.60 40
STE20-like serine/threonine-protein kinase SLK Tchem Kinase -2.33861 211.4 200
Dual specificity mitogen-activated protein kinase kinase 3 MAP2K3 Tchem Kinase -2.35301 190.9 1060