Development Level

Tclin 4 | 612

IMPC Phenotype

abnormal behavioral response t... 1 | 66
decreased lean body mass 1 | 135
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 4 | 11,493
Major Depressive Disorder 4 | 301
Migraine 4 | 83
Schizophrenia 4 | 1,160
Alcohol dependence 3 | 107
Alcoholic Intoxication, Chronic 3 | 289
Attention deficit hyperactivity disorder 3 | 278
Bipolar Disorder 3 | 666
Depressive disorder 3 | 409
Generalized anxiety disorder 3 | 29
Hypoactive sexual desire disorder 3 | 8
Mental Depression 3 | 333
Mood Disorders 3 | 184
Obesity 3 | 678
Parkinson's disease 3 | 392
Personality disorder 3 | 25
Substance abuse 3 | 59
Unipolar Depression 3 | 250
Agitation associated with Bipolar Mania 2 | 5
Agitation associated with Schizophrenia 2 | 5
Alcohol abuse 2 | 50
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Autistic Disorder 2 | 364
Bipolar affective disorder, current episode manic 2 | 13
Bipolar disorder in remission 2 | 19
Chronic thromboembolic pulmonary hypertension 2 | 4
Cocaine-Related Disorders 2 | 92
Depression Treatment Adjunct 2 | 5
Drug psychosis 2 | 7
Fever 2 | 138
Hyperactive behavior 2 | 91
Hyperkinesis 2 | 32
Hyperprolactinemia 2 | 27
Infantile autism 2 | 4
Lack or loss of sexual desire 2 | 3
Migraine Disorders 2 | 76
Migraine Prevention 2 | 23
Mixed bipolar I disorder 2 | 9
Panic disorder 2 | 61
Premature ejaculation 2 | 16
Schizoaffective Disorder 2 | 55
Seasonal affective disorder 2 | 28
Single major depressive episode 2 | 8
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
obsessive-compulsive disorder 2 | 61
oligodendroglioma 2 | 2,850
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
pulmonary arterial hypertension 2 | 76
Adverse reaction to drug 1 | 61
Alcoholism 1 | 45
Amenorrhea 1 | 58
Amnestic disorder 1 | 35
Angioedema 1 | 38
Bradycardia 1 | 36
Bulimia nervosa 1 | 14
Cardiomegaly 1 | 116
Chronic Obstructive Airway Disease 1 | 37
Chronic schizophrenia 1 | 16
Cocaine abuse 1 | 19
Delusional disorder 1 | 13
Depression, Postpartum 1 | 7
Drug-Related Side Effects and Adverse Reactions 1 | 62
Eating disorder 1 | 26
General anesthesia 1 | 53
Gilles de la Tourette syndrome 1 | 47
Heart Valve Diseases 1 | 25
Heart failure 1 | 162
Heart valve disease 1 | 39
Hypertension, Pulmonary 1 | 37
Intermittent migraine headaches 1 | 68
Irritable bowel syndrome 1 | 60
Melancholia 1 | 10
Memory Disorders 1 | 40
Metabolic Syndrome 1 | 20
Metabolic syndrome X 1 | 52
Motion sickness 1 | 21
Nasal congestion 1 | 23
Nausea 1 | 20
Nausea and vomiting 1 | 97
Obstructive sleep apnea 1 | 26
Pain 1 | 103
Prader-Willi syndrome 1 | 48
Progressive multifocal leukoencephalopathy 1 | 25
Psychoses, Substance-Induced 1 | 17
Pulmonary Disease, Chronic Obstructive 1 | 31
Pulmonary hypertension 1 | 86
Substance Withdrawal Syndrome 1 | 55
Sudden infant death syndrome 1 | 32
Treatment-resistant schizophrenia 1 | 6
Tremor 1 | 113
Weight Gain 1 | 100
lingual-facial-buccal dyskinesia 1 | 13
post-traumatic stress disorder 1 | 40

Tissue

Nervous System 4 | 16,725
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Male tissues 3 | 17,142
Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Liver and Pancreas 2 | 16,750
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

GPCR 4 | 408

GO Process

serotonin receptor signaling p... 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 2C HTR2C Tclin GPCR -3.08158 1199.3 336
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
5-hydroxytryptamine receptor 2A HTR2A Tclin GPCR -3.33563 2152.8 231
5-hydroxytryptamine receptor 1A HTR1A Tclin GPCR -3.67718 4891.4 254