Development Level

Tbio 103 | 10,625
Tdark 12 | 7,003
Tclin 11 | 602
Tchem 6 | 1,890

Collection

Eligible Ion Channel Proteins 3 | 117

IMPC Term

increased or absent threshold ... 9 | 128
decreased prepulse inhibition 6 | 52
abnormal behavior 5 | 226
decreased body length 5 | 108
decreased body weight 5 | 174
preweaning lethality, incomple... 5 | 260
absent startle reflex 4 | 15
decreased grip strength 4 | 123
decreased startle reflex 4 | 48
enlarged heart 4 | 111
absent pinna reflex 3 | 21
decreased circulating HDL chol... 3 | 77
decreased circulating amylase ... 3 | 24
decreased circulating choleste... 3 | 85
decreased lean body mass 3 | 195
embryonic lethality prior to t... 3 | 187
hyperactivity 3 | 108
increased circulating sodium l... 3 | 71
preweaning lethality, complete... 3 | 633
abnormal bone mineralization 2 | 55
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal eye morphology 2 | 38
abnormal locomotor activation 2 | 26
abnormal respiratory quotient 2 | 9
abnormal vibrissa morphology 2 | 17
decreased circulating alanine ... 2 | 53
decreased circulating free fat... 2 | 39
decreased circulating glucose ... 2 | 121
decreased circulating glycerol... 2 | 19
decreased circulating insulin ... 2 | 75
decreased circulating triglyce... 2 | 83
decreased hemoglobin content 2 | 53
decreased total body fat amoun... 2 | 186
hydrops fetalis 2 | 22
impaired righting response 2 | 19
increased body weight 2 | 42
increased circulating alkaline... 2 | 119
increased circulating chloride... 2 | 43
increased total body fat amoun... 2 | 57
stereotypic behavior 2 | 3
trunk curl 2 | 15
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal defecation 1 | 1
abnormal ear morphology 1 | 5
abnormal eye size 1 | 11
abnormal forebrain development 1 | 18
abnormal glucose homeostasis 1 | 5
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal motor coordination/ b... 1 | 4
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal tail morphology 1 | 17
abnormal testis morphology 1 | 30
abnormal vocalization 1 | 21
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating fructosa... 1 | 31
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased eosinophil cell numb... 1 | 41
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
embryonic lethality prior to o... 1 | 148
enlarged epididymis 1 | 27
improved glucose tolerance 1 | 56
increased NK T cell number 1 | 11
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating calcium ... 1 | 32
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean platelet volume 1 | 19
increased respiratory quotient 1 | 12
increased rib number 1 | 41
irregularly shaped pupil 1 | 7
limb grasping 1 | 35
microphthalmia 1 | 15
persistence of hyaloid vascula... 1 | 22
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
small adrenal glands 1 | 15
small testis 1 | 37
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

Nonsyndromic deafness 60 | 121
ovarian cancer 56 | 8,484
psoriasis 56 | 6,685
medulloblastoma, large-cell 53 | 6,234
Sensorineural hearing loss 47 | 107
glioblastoma 47 | 5,572
osteosarcoma 46 | 7,933
atypical teratoid / rhabdoid tumor 44 | 4,369
pilocytic astrocytoma 37 | 3,086
lung cancer 35 | 4,466
oligodendroglioma 34 | 2,849
Carcinoma 32 | 2,147
Breast cancer 31 | 3,094
interstitial cystitis 31 | 2,299
non-small cell lung cancer 30 | 2,798
primitive neuroectodermal tumor 30 | 3,031
invasive ductal carcinoma 29 | 2,950
ependymoma 28 | 2,514
lung carcinoma 28 | 2,844
pediatric high grade glioma 28 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,289
lung adenocarcinoma 24 | 2,713
pituitary cancer 24 | 1,972
adult high grade glioma 23 | 2,148
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
malignant mesothelioma 23 | 3,162
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,956
cystic fibrosis 20 | 1,665
ductal carcinoma in situ 20 | 1,745
adrenocortical carcinoma 19 | 1,427
medulloblastoma 19 | 1,524
Cancer 18 | 2,346
Pick disease 18 | 1,893
astrocytic glioma 18 | 2,241
breast carcinoma 18 | 1,614
group 4 medulloblastoma 18 | 1,875
Hodgkin's lymphoma, nodular sclerosis 17 | 24
astrocytoma 17 | 1,493
subependymal giant cell astrocytoma 17 | 2,287
Craniofacial Abnormalities 15 | 147
group 3 medulloblastoma 15 | 2,254
spina bifida 15 | 1,064
Epilepsy 14 | 346
posterior fossa group A ependymoma 14 | 1,511
sonic hedgehog group medulloblastoma 14 | 1,482
ulcerative colitis 14 | 2,087
pancreatic cancer 13 | 2,300
tuberculosis 13 | 1,557
atypical teratoid/rhabdoid tumor 12 | 1,095
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
posterior fossa group B ependymoma 12 | 1,530
Usher syndrome 11 | 34
nasopharyngeal carcinoma 11 | 1,056
Blindness 10 | 84
Cleft palate 10 | 125
Intellectual disability 10 | 573
Retinitis pigmentosa 10 | 153
Deafness 9 | 18
Rheumatoid Arthritis 9 | 1,160
acute quadriplegic myopathy 9 | 1,157
diabetes mellitus 9 | 1,663
esophageal adenocarcinoma 9 | 737
primary pancreatic ductal adenocarcinoma 9 | 1,271
Autistic Disorder 8 | 320
Down syndrome 8 | 548
colon cancer 8 | 1,475
dermatomyositis 8 | 933
gastric carcinoma 8 | 832
Multiple Sclerosis 7 | 498
Multiple myeloma 7 | 1,327
juvenile dermatomyositis 7 | 1,189
Alzheimer's disease 6 | 644
Attention deficit hyperactivity disorder 6 | 156
Enlarged vestibular aqueduct 6 | 10
Hypertensive disease 6 | 193
Inflammation 6 | 109
Obesity 6 | 616
aldosterone-producing adenoma 6 | 664
chronic rhinosinusitis 6 | 512
cutaneous lupus erythematosus 6 | 1,056
fibroadenoma 6 | 557
non primary Sjogren syndrome sicca 6 | 840
Atopic dermatitis 5 | 944
Cleft Lip 5 | 91
Diabetes Mellitus, Non-Insulin-Dependent 5 | 157
Duchenne muscular dystrophy 5 | 602
Glaucoma 5 | 134
Heart disease 5 | 279
Hypertension 5 | 287
Mammary Neoplasms 5 | 410
Neurodegenerative disease 5 | 383
Neuropathy 5 | 210
Osteoporosis 5 | 257
Peripheral Neuropathy 5 | 303
Schizophrenia 5 | 501
Toxic encephalopathy 5 | 131
Vascular disease 5 | 281
Waldenstrons macroglobulinemia 5 | 765
acute myeloid leukemia 5 | 780
urothelial carcinoma 5 | 318

Tissue

Digestive Tract 131 | 18,473
Endocrine System 131 | 18,512
Female tissues 131 | 18,647
Nervous System 131 | 18,561
Urinary Tract 131 | 18,444
Cardiovascular System 129 | 17,958
Skin and soft tissues 129 | 18,115
Liver and Pancreas 128 | 18,136
Blood and immune system 126 | 17,995
Male tissues 125 | 17,969
Respiratory system 124 | 17,484

Target Family

Non-IDG 74 | 11,971
Enzyme 20 | 4,146
Transcription Factor 12 | 1,400
Ion Channel 11 | 341
Transporter 8 | 473
GPCR 3 | 406
Kinase 2 | 634
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Process

sensory perception of sound 132 | 132
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stereocilin STRC Tbio Non-IDG 35.9 7
POU domain, class 3, transcription factor 4 POU3F4 Tbio Transcription Factor -2.24459 179.3 55
BarH-like 1 homeobox protein BARHL1 Tbio Transcription Factor -1.06351 11.8 78
Myelin basic protein MBP Tbio Non-IDG -3.69577 5257.0 715
Otoancorin OTOA Tdark Non-IDG -1.29628 19.3 48
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -1.97274 103.1 38
Transmembrane O-methyltransferase LRTOMT Tbio Enzyme 13.4 29
Collagen alpha-1(XI) chain COL11A1 Tbio Non-IDG -2.09756 129.5 88
60S ribosomal protein L38 RPL38 Tdark Non-IDG -1.39563 24.2 45