Development Level

Tbio 107 | 11,445
Tclin 11 | 613
Tchem 9 | 1,598
Tdark 8 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

increased or absent threshold ... 9 | 101
preweaning lethality, incomple... 7 | 499
preweaning lethality, complete... 6 | 979
decreased body weight 5 | 161
decreased prepulse inhibition 5 | 82
abnormal behavior 4 | 298
absent startle reflex 4 | 24
decreased circulating amylase ... 4 | 28
decreased startle reflex 4 | 75
increased circulating sodium l... 4 | 71
absent pinna reflex 3 | 23
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
hyperactivity 3 | 148
increased lean body mass 3 | 172
abnormal bone mineralization 2 | 38
abnormal embryo size 2 | 220
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal locomotor activation 2 | 16
abnormal vibrissa morphology 2 | 25
decreased body length 2 | 101
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased hemoglobin content 2 | 68
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
impaired righting response 2 | 26
increased thermal nociceptive ... 2 | 9
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
short tibia 2 | 97
stereotypic behavior 2 | 3
tremors 2 | 39
trunk curl 2 | 16
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal defecation 1 | 1
abnormal ear morphology 1 | 9
abnormal eye size 1 | 7
abnormal skin condition 1 | 6
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
convulsive seizures 1 | 13
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lumbar vertebrae num... 1 | 2
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
hydrops fetalis 1 | 1
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
increased urine magnesium leve... 1 | 2
increased vertical activity 1 | 24
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
small adrenal glands 1 | 16
small spleen 1 | 19
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 99 | 11,493
Nonsyndromic deafness 61 | 142
ovarian cancer 60 | 8,520
psoriasis 57 | 6,694
medulloblastoma, large-cell 55 | 6,241
atypical teratoid / rhabdoid tumor 54 | 5,112
glioblastoma 51 | 5,792
osteosarcoma 47 | 7,950
ependymoma 46 | 4,679
Autosomal recessive predisposition 44 | 1,442
Breast cancer 44 | 3,578
Sensorineural hearing loss 44 | 106
Kidney cancer 41 | 2,613
group 3 medulloblastoma 41 | 4,104
adult high grade glioma 40 | 3,801
lung cancer 40 | 4,740
Astrocytoma, Pilocytic 37 | 3,081
Sensorineural Hearing Loss (disorder) 37 | 284
oligodendroglioma 34 | 2,850
non-small cell lung cancer 33 | 2,890
interstitial cystitis 31 | 2,312
invasive ductal carcinoma 31 | 2,951
primitive neuroectodermal tumor 30 | 3,035
lung carcinoma 28 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
lung adenocarcinoma 26 | 2,716
pituitary cancer 26 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
Schizophrenia 24 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
astrocytic glioma 23 | 2,597
Deafness 22 | 198
malignant mesothelioma 22 | 3,232
Epilepsy 21 | 792
cystic fibrosis 21 | 1,696
ductal carcinoma in situ 21 | 1,745
Cancer 20 | 2,499
Intellectual disability 20 | 1,016
hearing impairment 20 | 199
Pick disease 19 | 1,894
adrenocortical carcinoma 19 | 1,428
breast carcinoma 19 | 1,638
pancreatic cancer 18 | 2,398
Congenital deafness 17 | 185
Dull intelligence 17 | 645
Hearing Loss, Partial 17 | 185
Low intelligence 17 | 645
Mental Retardation 17 | 645
Mental deficiency 17 | 645
Poor school performance 17 | 645
subependymal giant cell astrocytoma 17 | 2,287
Craniofacial Abnormalities 16 | 151
Melanoma 16 | 711
group 4 medulloblastoma 16 | 1,855
tuberculosis 16 | 2,010
Bipolar Disorder 15 | 666
Hodgkin's lymphoma, nodular sclerosis 14 | 22
Skin cancer 14 | 469
spina bifida 14 | 1,074
Cataract 13 | 297
Cleft Palate 13 | 271
Liver cancer 13 | 604
Myopia 13 | 176
astrocytoma 13 | 1,146
nasopharyngeal carcinoma 13 | 1,058
ulcerative colitis 13 | 1,819
Cognitive delay 12 | 608
Conductive hearing loss 12 | 123
Global developmental delay 12 | 608
Lens Opacities 12 | 231
Mental and motor retardation 12 | 608
Seizures 12 | 596
Short stature 12 | 531
pediatric high grade glioma 12 | 1,064
Glaucoma 11 | 239
Retinitis Pigmentosa 11 | 226
Usher syndrome 11 | 32
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Blindness 10 | 88
Concave bridge of nose 10 | 195
Depressed nasal bridge 10 | 195
Depressed nasal root/bridge 10 | 195
Hypertension 10 | 396
Hypotrophic malar bone 10 | 129
Malar flattening 10 | 129
Nystagmus 10 | 317
Rheumatoid arthritis 10 | 1,191
Uranostaphyloschisis 10 | 167
diabetes mellitus 10 | 1,728
Anteverted nostril 9 | 191
Attention deficit hyperactivity disorder 9 | 278
Autistic Disorder 9 | 364
Blindness, Legal 9 | 110
Depressive disorder 9 | 409
Endometrial cancer 9 | 311
Exophthalmos 9 | 112
Low set ears 9 | 181
Mental Depression 9 | 333
Muscle hypotonia 9 | 571
Obesity 9 | 678

Tissue

Endocrine System 130 | 18,159
Digestive Tract 125 | 17,369
Female tissues 125 | 17,400
Male tissues 125 | 17,142
Skin and soft tissues 124 | 17,230
Nervous System 123 | 16,725
Liver and Pancreas 119 | 16,750
Urinary Tract 117 | 16,678
Blood and immune system 116 | 16,909
Respiratory system 114 | 16,393
Cardiovascular System 100 | 15,192

Target Family

Non-IDG 73 | 12,091
Enzyme 22 | 4,145
Transcription Factor 12 | 1,400
Ion Channel 11 | 344
Transporter 8 | 473
Kinase 4 | 634
GPCR 3 | 408
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Process

sensory perception of sound 135 | 135
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutaredoxin domain-containing cysteine-rich protein 2 GRXCR2 Tbio Non-IDG 0.00000 1.00 14
Mitochondrial import inner membrane translocase subunit Tim13 TIMM13 Tbio Enzyme -1.90930 75.7 32
Mitochondrial import inner membrane translocase subunit Tim9 TIMM9 Tbio Enzyme -1.31703 21.3 72
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Mitochondrial import inner membrane translocase subunit Tim8 B TIMM8B Tbio Enzyme -1.46649 28.6 54
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 Tclin Enzyme -2.43529 263.5 165
F-box only protein 11 FBXO11 Tbio Non-IDG -1.53905 34.1 258
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188