Development Level

Tbio 20 | 11,651
Tclin 18 | 612
Tchem 14 | 1,388
Tdark 1 | 6,593

Collection

RFA-RM-18-021 4 | 328
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal behavior 3 | 298
preweaning lethality, complete... 3 | 979
edema 2 | 59
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal locomotor activation 1 | 16
abnormal spine curvature 1 | 9
absent testes 1 | 6
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating glycerol... 1 | 16
decreased circulating serum al... 1 | 82
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating total pr... 1 | 28
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112

Disease

Carcinoma 32 | 11,493
medulloblastoma, large-cell 27 | 6,241
glioblastoma 24 | 5,792
osteosarcoma 24 | 7,950
ovarian cancer 24 | 8,520
atypical teratoid / rhabdoid tumor 23 | 5,112
ependymoma 23 | 4,679
adult high grade glioma 22 | 3,801
psoriasis 22 | 6,694
Astrocytoma, Pilocytic 20 | 3,081
Schizophrenia 20 | 1,160
lung cancer 18 | 4,740
oligodendroglioma 18 | 2,850
Depressive disorder 17 | 409
Cancer 16 | 2,499
Epilepsy 16 | 792
group 3 medulloblastoma 16 | 4,104
Hyperalgesia 15 | 83
astrocytic glioma 15 | 2,597
colon cancer 15 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
Mental Depression 14 | 333
Pain 14 | 103
Pain agnosia 14 | 104
lung carcinoma 14 | 2,843
Alcoholic Intoxication, Chronic 13 | 289
Breast cancer 13 | 3,578
Obesity 13 | 678
invasive ductal carcinoma 13 | 2,951
lung adenocarcinoma 13 | 2,716
malignant mesothelioma 13 | 3,232
Bipolar Disorder 12 | 666
Parkinson's disease 12 | 392
Seizures 12 | 596
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
non-small cell lung cancer 12 | 2,890
primitive neuroectodermal tumor 12 | 3,035
interstitial cystitis 11 | 2,312
subependymal giant cell astrocytoma 11 | 2,287
Alzheimer's disease 10 | 658
Kidney cancer 10 | 2,613
Pick disease 10 | 1,894
ulcerative colitis 10 | 1,819
Neuropathy 9 | 261
Substance Withdrawal Syndrome 9 | 55
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Constipation 8 | 181
Major Depressive Disorder 8 | 301
Mood Disorders 8 | 184
Neurodegenerative disease 8 | 414
Toxic encephalopathy 8 | 141
diabetes mellitus 8 | 1,728
ductal carcinoma in situ 8 | 1,745
Alcohol dependence 7 | 107
Asthma 7 | 385
Attention deficit hyperactivity disorder 7 | 278
Autosomal recessive predisposition 7 | 1,442
Cocaine-Related Disorders 7 | 92
Cognitive delay 7 | 608
Disease Models, Animal 7 | 155
Global developmental delay 7 | 608
Hypertension 7 | 396
Inflammation 7 | 120
Local anesthesia 7 | 40
Mental and motor retardation 7 | 608
Opiate dependence 7 | 29
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
pituitary cancer 7 | 1,972
tuberculosis 7 | 2,010
Alcoholism 6 | 45
Arthritis 6 | 290
Autistic Disorder 6 | 364
Cerebrovascular disease 6 | 238
Chronic pain 6 | 9
Cocaine Dependence 6 | 51
Intellectual disability 6 | 1,016
Kidney disease 6 | 430
Migraine 6 | 83
Multiple Sclerosis 6 | 540
Psychotic Disorders 6 | 151
Unipolar Depression 6 | 250
adrenocortical carcinoma 6 | 1,428
aldosterone-producing adenoma 6 | 665
medulloblastoma 6 | 720
Cardiomyopathies 5 | 110
Cerebellar Ataxia 5 | 304
Diarrhea 5 | 253
Gastroesophageal reflux disease 5 | 110
Heart disease 5 | 306
Infantile onset 5 | 238
Melanoma 5 | 711
Muscle hypotonia 5 | 571
Nerve Degeneration 5 | 121
Pain disorder 5 | 15
Prostatic Neoplasms 5 | 495
Vascular disease 5 | 319
acute myeloid leukemia 5 | 783
astrocytoma 5 | 1,146
pancreatic cancer 5 | 2,398

Tissue

Endocrine System 53 | 18,159
Female tissues 51 | 17,400
Nervous System 51 | 16,725
Male tissues 48 | 17,142
Blood and immune system 47 | 16,909
Digestive Tract 47 | 17,369
Skin and soft tissues 47 | 17,230
Liver and Pancreas 45 | 16,750
Respiratory system 45 | 16,393
Urinary Tract 45 | 16,678
Cardiovascular System 37 | 15,192

Target Family

GPCR 13 | 408
Ion Channel 13 | 344
Non-IDG 13 | 12,091
Enzyme 6 | 4,145
Kinase 4 | 634
Transcription Factor 3 | 1,400
TF/Epigenetic 1 | 38

GO Process

sensory perception of pain 53 | 53
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Disks large homolog 2 DLG2 Tbio Non-IDG -1.75838 53.6 227
Cyclin-dependent-like kinase 5 CDK5 Tchem Kinase -3.06393 1238.4 694
Potassium voltage-gated channel subfamily D member 2 KCND2 Tclin Ion Channel -2.39309 245.7 317
Substance-P receptor TACR1 Tclin GPCR -3.10271 1238.0 435
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
Prokineticin-2 PROK2 Tbio Non-IDG -2.23239 181.5 138
Glutamate receptor ionotropic, NMDA 2A GRIN2A Tclin Ion Channel -3.09828 1158.1 555
Hydroperoxide isomerase ALOXE3 ALOXE3 Tbio Enzyme -1.51120 32.2 118