Development Level

Tbio 32 | 11,445
Tdark 4 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased circulating creatini... 2 | 39
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating fructosa... 1 | 30
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased startle reflex 1 | 112
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
thrombocytosis 1 | 27

Disease

Carcinoma 32 | 11,493
psoriasis 16 | 6,694
acute quadriplegic myopathy 14 | 1,158
lung adenocarcinoma 13 | 2,716
osteosarcoma 13 | 7,950
ovarian cancer 12 | 8,520
Autosomal recessive predisposition 11 | 1,442
Dilated cardiomyopathy 11 | 56
Kidney cancer 11 | 2,613
atypical teratoid / rhabdoid tumor 11 | 5,112
Cardiomyopathy 10 | 116
Cardiomyopathy, Dilated 10 | 83
glioblastoma 10 | 5,792
medulloblastoma, large-cell 10 | 6,241
Breast cancer 9 | 3,578
Familial isolated dilated cardiomyopathy 9 | 41
LEFT VENTRICULAR NONCOMPACTION 10 9 | 40
LEFT VENTRICULAR NONCOMPACTION 8 9 | 40
Hypertrophic Cardiomyopathy 8 | 117
lung cancer 8 | 4,740
malignant mesothelioma 8 | 3,232
Muscle Weakness 7 | 170
Myopathy 7 | 185
ependymoma 7 | 4,679
pediatric high grade glioma 7 | 1,064
Astrocytoma, Pilocytic 6 | 3,081
Distal arthrogryposis 6 | 42
Duchenne muscular dystrophy 6 | 601
breast carcinoma 6 | 1,638
diabetes mellitus 6 | 1,728
primitive neuroectodermal tumor 6 | 3,035
Cancer 5 | 2,499
Creatine phosphokinase serum increased 5 | 110
Elevated creatine kinase 5 | 110
Heart disease 5 | 306
colon cancer 5 | 1,478
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
pancreatic cancer 5 | 2,398
Amyotrophic lateral sclerosis 4 | 451
Congestive heart failure 4 | 113
Heart failure 4 | 162
Liver Cirrhosis, Experimental 4 | 769
Liver cancer 4 | 604
Melanoma 4 | 711
Myocardial Infarction 4 | 151
Nemaline myopathy 4 | 17
Pick disease 4 | 1,894
Short stature 4 | 531
Skin cancer 4 | 469
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
hereditary spastic paraplegia 4 | 318
limb-girdle muscular dystrophy 4 | 37
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
non-small cell lung carcinoma 4 | 317
Adenoma 3 | 167
Becker muscular dystrophy 3 | 191
Cardiac Arrhythmia 3 | 103
Cardiac conduction abnormalities 3 | 78
Cardiomyopathies 3 | 110
Cardiomyopathy, Hypertrophic, Familial 3 | 9
Conduction disorder of the heart 3 | 79
Cryptorchidism 3 | 296
EKG abnormalities 3 | 78
Electrocardiogram abnormal 3 | 81
Electrocardiogram change 3 | 78
Fetal Growth Retardation 3 | 189
Hypotrophic malar bone 3 | 129
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Left ventricular noncompaction 3 | 26
Long philtrum 3 | 137
Malar flattening 3 | 129
Muscle biopsy shows dystrophic changes 3 | 39
Muscular dystrophy 3 | 75
Osteoporosis 3 | 363
Primary cutaneous amyloidosis 3 | 29
Sudden death 3 | 16
astrocytoma 3 | 1,146
cystic fibrosis 3 | 1,696
fibroadenoma 3 | 559
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
limb girdle muscular dystrophy 2A 3 | 213
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Adducted thumb 2 | 22
Arthrogryposis 2 | 54
Blepharoptosis 2 | 231
Broad forehead 2 | 59
Multiple pterygium syndrome 2 | 18
Protruding ears 2 | 56
Triangular face 2 | 58
Vertical Talus 2 | 25

Tissue

Female tissues 38 | 17,400
Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Urinary Tract 36 | 16,678
Blood and immune system 35 | 16,909
Cardiovascular System 35 | 15,192
Liver and Pancreas 35 | 16,750
Male tissues 35 | 17,142
Skin and soft tissues 35 | 17,230
Nervous System 33 | 16,725
Respiratory system 31 | 16,393

Target Family

Non-IDG 31 | 12,091
Kinase 3 | 634
Transcription Factor 3 | 1,400
Enzyme 1 | 4,145

GO Process

sarcomere organization 38 | 38
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Keratin, type II cytoskeletal 8 KRT8 Tbio Non-IDG -2.87670 710.7 1827
Homeobox protein SIX4 SIX4 Tbio Transcription Factor -2.31722 197.8 141
Immunoglobulin superfamily member 22 IGSF22 Tdark Non-IDG 0.48 0.33 16
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Leiomodin-2 LMOD2 Tbio Non-IDG -0.89671 9.37 55
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Titin TTN Tbio Kinase -3.24415 1743.0 123
Myosin-3 MYH3 Tbio Non-IDG -1.74714 48.2 51
Calsequestrin-1 CASQ1 Tbio Non-IDG -1.96476 86.8 103