Development Level

Tbio 21 | 11,445
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
cataract 1 | 92
decreased body length 1 | 101
decreased cardiac output 1 | 3
decreased cardiac stroke volum... 1 | 6
decreased circulating aspartat... 1 | 34
decreased coping response 1 | 8
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66

Disease

ovarian cancer 12 | 8,520
Carcinoma 10 | 11,493
lung cancer 9 | 4,740
osteosarcoma 9 | 7,950
colon cancer 7 | 1,478
psoriasis 7 | 6,694
Diamond-Blackfan anemia 6 | 31
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Abnormality of the urinary system 4 | 21
Anemia 4 | 365
Anemia, Diamond-Blackfan 4 | 16
Anemia, Macrocytic 4 | 18
Cardiac Arrhythmia 4 | 103
Cardiac conduction abnormalities 4 | 78
Cleft Palate 4 | 271
Conduction disorder of the heart 4 | 79
Delayed Puberty 4 | 97
EKG abnormalities 4 | 78
Electrocardiogram abnormal 4 | 81
Electrocardiogram change 4 | 78
Fatigue 4 | 182
Hand deformities 4 | 32
Intermittent migraine headaches 4 | 68
Migraine Disorders 4 | 76
Pallor 4 | 40
Uranostaphyloschisis 4 | 167
Waldenstrons macroglobulinemia 4 | 765
adult high grade glioma 4 | 3,801
diabetes mellitus 4 | 1,728
genital abnormal 4 | 17
glioblastoma 4 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
medulloblastoma, large-cell 4 | 6,241
reproductive system abnormality 4 | 17
sonic hedgehog group medulloblastoma 4 | 467
Breast cancer 3 | 3,578
Multiple myeloma 3 | 1,332
acute myeloid leukemia 3 | 783
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
subependymal giant cell astrocytoma 3 | 2,287
Adenocarcinoma of lung 2 | 142
Cancer 2 | 2,499
Disease Models, Animal 2 | 155
Mean cell volume increased 2 | 5
Shwachman-Diamond syndrome 2 | 17
acute quadriplegic myopathy 2 | 1,158
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
mucosa-associated lymphoid tissue lymphoma 2 | 484
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Absent auditory canals 1 | 23
Absent external auditory canals 1 | 23
Acute Promyelocytic Leukemia 1 | 40
Amyotrophic lateral sclerosis 1 | 451
Atresia of the external auditory canal 1 | 23
Atretic auditory canal 1 | 23
Autosomal dominant Robinow syndrome 1 1 | 15
Autosomal recessive Robinow syndrome 1 | 27
Bruxism 1 | 18
Carcinoma, Renal Cell 1 | 124
Cardiovascular system disease 1 | 246
Coronary Restenosis 1 | 8
Denys-Drash syndrome 1 | 12
DiGeorge syndrome 1 | 47
Gaucher disease type 1 1 | 180
Guillain-Barre syndrome 1 | 14
HIV Infections 1 | 102
Intracranial hypotension 1 | 10
Leukemia, Acute Myeloid 1 | 17
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Leukemia, Promyelocytic, Acute 1 | 36
Leukopenia 1 | 72
Liver neoplasms 1 | 130
Melanoma 1 | 711
Mixed connective tissue disease 1 | 16
Myocardial Infarction 1 | 151
Neutrophil count decreased 1 | 47
Ovarian Cysts 1 | 41
Parkinson Disease 1 | 64
Parkinson's disease 1 | 392
Penile hypospadias 1 | 106
Pericarditis 1 | 13
Posterior amorphous corneal dystrophy 1 | 9
Precancerous Conditions 1 | 80
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1 | 25
Prostate carcinoma in situ 1 | 11
Pulmonary embolism 1 | 55
Renal Cell Carcinoma 1 | 214
Retinitis pigmentosa 23 1 | 27
Sarcoma 1 | 62
inflammatory breast cancer 1 | 286

Tissue

Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678

Target Family

Non-IDG 25 | 12,091
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

GO Process

ribosomal large subunit biogen... 27 | 27
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
p21-activated protein kinase-interacting protein 1 PAK1IP1 Tbio Enzyme -1.02033 9.87 62
60S ribosomal protein L26 RPL26 Tbio Non-IDG -1.66446 44.8 126
60S ribosomal protein L26-like 1 RPL26L1 Tdark Non-IDG 0.30 0.50 77
Protein SDA1 homolog SDAD1 Tdark Non-IDG -0.10834 1.45 27
Transcription factor IIIA GTF3A Tbio Transcription Factor -2.35179 204.7 171
Ribosome production factor 2 homolog RPF2 Tbio Non-IDG -0.85431 7.55 124
Surfeit locus protein 6 SURF6 Tbio Non-IDG -1.17946 18.2 101
Zinc finger protein 622 ZNF622 Tbio Non-IDG -0.35402 2.96 131
Mitochondrial assembly of ribosomal large subunit protein 1 MALSU1 Tbio Non-IDG -0.60206 4.00 45
60S ribosomal protein L5 RPL5 Tbio Non-IDG -2.02831 78.3 228