Development Level

Tbio 7 | 11,445
Tclin 3 | 613
Tchem 2 | 1,598

IMPC Phenotype

abnormal heart morphology 2 | 162
enlarged heart 2 | 210
abnormal behavior 1 | 298
abnormal whole-body plethysmog... 1 | 4
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating triglyce... 1 | 79
decreased lymphocyte cell numb... 1 | 83
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood uric acid leve... 1 | 5
increased cellular hemoglobin ... 1 | 1
increased circulating potassiu... 1 | 29
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
macrophthalmia 1 | 2
prolonged PR interval 1 | 15

Disease

Autosomal recessive predisposition 9 | 1,442
Carcinoma 9 | 11,493
Difficulties with night vision 9 | 87
Night Blindness 9 | 101
Glaucoma 8 | 239
Intellectual disability 8 | 1,016
Retinitis Pigmentosa 8 | 226
Abnormality of retinal pigmentation 7 | 111
Abnormality of the retinal vasculature 7 | 59
Anteverted nostril 7 | 191
Atypical scarring of skin 7 | 62
Blind Vision 7 | 111
Blindness, Legal 7 | 110
Broad flat nasal bridge 7 | 236
Cataract 7 | 297
Conductive hearing loss 7 | 123
Congenital anomaly of testis 7 | 52
Congenital hypoplasia of penis 7 | 176
Dull intelligence 7 | 645
Electroretinogram abnormal 7 | 95
Hyperinsulinism 7 | 133
Hypogonadism 7 | 173
Keratoconus 7 | 113
Lens Opacities 7 | 231
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Nasal bridge wide 7 | 236
Night blindness, progressive 7 | 51
Nystagmus 7 | 317
Obesity 7 | 678
Ophthalmoplegia 7 | 106
Optic Atrophy 7 | 242
Photodysphoria 7 | 121
Photophobia 7 | 121
Poor school performance 7 | 645
Retinal pigment epithelial abnormality 7 | 111
Sensorineural Hearing Loss (disorder) 7 | 284
psoriasis 6 | 6,694
Abnormality of macular pigmentation 5 | 16
Congenital stationary night blindness 5 | 29
Hypoplasia of optic disc 5 | 12
Macular pigmentary changes 5 | 16
Night blindness, congenital stationary 5 | 16
Night blindness, congenital stationary, complete 5 | 10
Night blindness, stationary 5 | 10
Oguchi disease 5 | 10
Reduced visual acuity 5 | 63
Retinal Degeneration 5 | 106
Severe myopia 5 | 22
Blindness 4 | 88
Atrial Fibrillation 3 | 124
Chronic heart failure 3 | 46
Fundus dystrophy 3 | 83
Myocardial Perfusion Imaging Adjunct 3 | 25
Platelet Aggregation Inhibition 3 | 22
Prevention of Cerebral Thrombosis 3 | 29
medulloblastoma, large-cell 3 | 6,241
Attenuation of retinal blood vessels 2 | 16
Cone dystrophy 2 | 71
Decreased amplitudes on flash visual electroretinogram 2 | 13
Diabetic retinopathy 2 | 56
Fundus albipunctatus 2 | 10
Fundus with peripheral 'bony spicules' 2 | 12
Leber congenital amaurosis 2 | 69
Loss of peripheral vision 2 | 5
Low Vision 2 | 174
Oguchi Disease 1 2 | 2
Pallor of optic disc 2 | 39
Tunnel visual field constriction 2 | 5
Uveitis 2 | 103
Visual Impairment 2 | 174
Visual field constriction 2 | 36
active Crohn's disease 2 | 922
group 3 medulloblastoma 2 | 4,104
lung adenocarcinoma 2 | 2,716
non primary Sjogren syndrome sicca 2 | 891
osteosarcoma 2 | 7,950
Age related macular degeneration 1 | 72
Anxiety Disorders 1 | 38
Arts syndrome 1 | 26
Chorioretinal atrophy 1 | 11
Chorioretinitis 1 | 6
Disease Models, Animal 1 | 155
Hemeralopia 1 | 4
MYELODYSPLASTIC SYNDROME 1 | 53
Macular retinal edema 1 | 13
Ocular hypertension 1 | 42
Optic nerve disease 1 | 10
Pain agnosia 1 | 104
Pigmentary retinal degeneration 1 | 11
Retinal exudates 1 | 11
Retinitis 1 | 7
Retinitis pigmentosa 1 1 | 6
Retinitis pigmentosa 47 1 | 4
Retinitis pigmentosa 49 1 | 14
Tularemia 1 | 23
chronic kidney disease 1 | 90
cone-rod dystrophy 1 | 59
inflammatory breast cancer 1 | 286

Tissue

Endocrine System 11 | 18,159
Digestive Tract 9 | 17,369
Female tissues 9 | 17,400
Nervous System 9 | 16,725
Skin and soft tissues 9 | 17,230
Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Male tissues 7 | 17,142
Urinary Tract 7 | 16,678
Liver and Pancreas 6 | 16,750
Respiratory system 6 | 16,393

Target Family

Non-IDG 4 | 12,091
Enzyme 3 | 4,145
GPCR 2 | 408
Ion Channel 2 | 344
Kinase 1 | 634

GO Process

rhodopsin mediated signaling p... 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha PDE6A Tclin Enzyme -1.29228 20.3 111
Melanopsin OPN4 Tbio GPCR -2.77246 589.6 65
cGMP-gated cation channel alpha-1 CNGA1 Tchem Ion Channel -1.86143 69.8 62
Guanine nucleotide-binding protein G(T) subunit gamma-T1 GNGT1 Tbio Non-IDG -1.43842 22.5 61
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GNB1 Tbio Non-IDG -1.22176 19.3 165
Rhodopsin kinase GRK1 Tchem Kinase -2.00623 82.1 224
Rhodopsin RHO Tbio GPCR -3.79531 6099.3 424
Guanine nucleotide-binding protein G(t) subunit alpha-1 GNAT1 Tbio Non-IDG -1.41254 22.0 137
S-arrestin SAG Tbio Non-IDG -3.22575 1575.2 151
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta PDE6B Tclin Enzyme -2.70127 507.4 69